Results 81 to 90 of about 234,036 (207)

Target-selective joint polymerase chain reaction: A robust and rapid method for high-throughput production of recombinant monoclonal antibodies from single cells

BMC Biotechnology, 2011
Background During the development of a therapeutic antibody, large numbers of monoclonal antibodies are required to screen for those that are best suited for the desired activity.
Isobe Masaharu, Kurosawa Nobuyuki, Yoshioka Megumi   +2 more
doaj   +1 more source

Identification and expression of a murine cytomegalovirus early gene coding for an Fc receptor [PDF]

, 1994
Several herpesviruses, including cytomegalovirus, induce receptors for the Fc domain of murine immunoglobulin G (IgG) molecules. Viral genes coding for these receptors have been characterized only for alphaherpesviruses. In this report, we describe a new
Ulrich, Eggers, Maren, H. Koszinowski, Regine Thale, Karin Schneider, Thäle, Regine, Koszinowski, Ulrich H., Lucin, Pero, Schneider, Karin, Maren Eggers, Pero Lucin   +10 more
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Organization of immunoglobulin genes.

, 1981
Includes bibliographical references.Organization and expression of murine immunoglobulin genes / Jerry M. Adams -- Rearrangements of immunoglobulin genes during differentiation and evolution / Tasuku Honjo -- Human antibody genes: V gene variability and ...

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Phylogenetic analysis of mammalian immunoglobulin gamma genes.

, 2012
The phylogenetic tree was constructed from the amino acid sequences of the CH2 and CH3 exons with various mammalian species immunoglobulin gamma gene. The guinea pig IgG genes were clustered with rodents IgG genes.
Qingyong Meng (156389), Liming Ren (135229), Yongchen Guo (156383), Qingwen Meng (156386), Yaofeng Zhao (135231), Yonghua Bao (156384), Xiaoxiang Hu (118803), Ning Li (45258)   +7 more
core   +1 more source

Cloning of the Complete Gene for Carcinoembryonic Antigen [PDF]

, 1990
Carcinoembryonic antigen (CEA) is a widely used tumor marker, especially in the surveillance of colonic cancer patients. Although CEA is also present in some normal tissues, it is apparently expressed at higher levels in tumorous tissues than in ...
Schrewe, Heinrich, Bona, Marion, Zimmermann, Wolfgang, Shively, John E., Hassauer, Martin, Hefta, Laura J. F., Maruya, Aiko, Thompson, John A., Kleist, Sabine von   +8 more
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Immunoglobulin replacement therapies in inborn errors of immunity: a review

Frontiers in Pediatrics
Immunoglobulins (Ig) were used as a therapeutic modality for the first time in a patient with X-linked agammaglobulinemia in 1952 by Colonel Ogden Bruton, decades before the molecular mechanisms causing the disease were unraveled.
Archan Sil, Suprit Basu, Vibhu Joshi, Rakesh Kumar Pilania, Sangeetha Siniah, Deepti Suri, Amit Rawat, Surjit Singh   +7 more
doaj   +1 more source

Assessment of humoral immunity in workers occupationally exposed to low levels of ionizing radiation [PDF]

Background: The aim of this study was investigating the effect of low levels of ionizing radiation on immunoglobulin, complement levels in radiology workers occupationally exposed to ionizing radiation.
رفاهی, سهیلا, رجائی اسكوئی, مهرانگیز, پورعیسی, مسعود, تبرائی, یاسر   +3 more
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Monitoring measurable residual disease in paediatric acute lymphoblastic leukaemia using immunoglobulin gene clonality based on next-generation sequencing

Cancer Cell International
Background Assessment of measurable residual disease (MRD) is an essential prognostic tool for B-lymphoblastic leukaemia (B-ALL). In this study, we evaluated the utility of next-generation sequencing (NGS)–based MRD assessment in real-world clinical ...
Won Kee Ahn, Kyunghee Yu, Hongkyung Kim, Seung-Tae Lee, Jong Rak Choi, Jung Woo Han, Chuhl Joo Lyu, Seungmin Hahn, Saeam Shin   +8 more
doaj   +1 more source

Identification and functional characterization of the novel MAR-binding protein, SATB2 [PDF]

, 2004
The regulation of gene expression is governed in large part by transcription factors that bind to enhancers and promoters. The functions of transcription factors involve both the modulation of chromatin accessibility via the recruitment of histone ...
Dobreva, Gergana
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IL28B, HLA-C, and KIR variants additively predict response to therapy in chronic Hepatitis C virus infection in a European cohort: A cross-sectional study

, 2011
Background To date, drug response genes have not proved as useful in clinical practice as was anticipated at the start of the genomic era. An exception is in the treatment of chronic hepatitis C virus (HCV) genotype 1 infection with pegylated interferon-
Hellard, M, Powell, Elizabeth, Ahlenstiel, G., Smedile, Antonina, Bassendine, Margaret, Hammond, E., O'Connor, Kate S, Armstrong, Nicola J, Stewart, Graeme J, Müller Tobias, Silvana Gaudieri, Mallal Simon, Armstrong Nicola J., Powell Elizabeth, Graeme J Stewart, Bassendine, M, Abate, ML, Jacob Nattermann, Irving, WL, Ahlenstiel, G, Simon Mallal, Negro, F, Stewart, Graeme J., Suppiah, Vijayaprakash, Matthews, G, Suppiah Vijayaprakash, Gaudieri Silvana, Bochud Pierre-Yves, null null, Nattermann, J, Vijayaprakash Suppiah, Hammond, Emma, Graeme J. Stewart, Hellard Margaret, Bochud, P-Y, Mallal, S., Negro, F., Ahlenstiel, Golo (R18999), O'Connor, KS, Smedile, A, Booth, DR, Powell, E, George Jacob, Gaudieri, S., Negro Francesco, Pierre-Yves Bochud, Irving, W.L., David Dunn, Abate, Maria L., Dore Gregory J., Hellard, M., International Hepatitis C Genetics Consortium (IHCGC), Spengler, U., William L Irving, Dunn David, David Sheridan, Riordan Stephen, Berg Thomas, Dunn, D.S., Stewart Graeme J., Mathews, Gail, Weltman, Martin, Ulrich Spengler, Nattermann Jacob, Mallai, Simon, Dunn, D, Francesco Negro, Berg, Thomas, for the International Hepatitis C Genetics Consortium (IHCGC), Gregory J. Dore, Sheridan, D, Abate Maria Lorena, Jacob George, Nicola J Armstrong, Matthews Gail, Mallal, S, Matthews, Gail, Booth, David R, Dore, G.J., Müller, T., Kate S O'Connor, Armstrong, Nicola J., Dore, Gregory J, Gail Matthews, Spengler Ulrich, Müller, T, Booth, David R., Berg, T., Irving, William L., Spengler, U, Booth, D.R., Spengler, Ulrich, Suppiah, V, Powell, E., Martin Weltman, Emma Hammond, Dunn, David, Thomas Berg, Suppiah, Vijay, Matthews, G., Abate, Maria Lorena, Bassendine, M., Berg, T, Riordan, Stephen, Hammond, E, Muller, Tobias, Ahlenstiel, Golo, Nattermann, J., Sheridan David, Smedile Antonina, Kate S. O'Connor, Mallal, Simon, Sheridan, D., Hammond Emma, David R. Booth, Irving William L., Stewart, GJ, Maria Lorena Abate, O'Connor, Kate S., Antonina Smedile, Golo Ahlenstiel, Armstrong, N.J., Margaret Hellard, Dore, GJ, O'Connor Kate S., Gaudieri, S, Hellard, Margaret, David R Booth, Weltman Martin, Riordan, S, Irving, William L, Margaret Bassendine, Tobias Müller, Armstrong, NJ, Weltman, M., Bassendine Margaret, Booth David R., Elizabeth Powell, Smedile, A., William L. Irving, Dore, Gregory J., Stephen Riordan, Weltman, M, Sheridan, David, Negro, Francesco, Bochud, PY, Riordan, S., Bochud, Pierre-Yves, Gregory J Dore, O'Connor, K.S., George, J, Nicola J. Armstrong, Suppiah, V., Stewart, G.J., Ahlenstiel Golo, George, J., George, Jacob, Nattermann, Jacob, Abate, M.L., Gaudieri, Silvana   +159 more
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