Results 181 to 190 of about 224,267 (330)

The two novel MHC class II transactivators RFX5 and CIITA both control expression of HLA-DM genes.

International Immunology, 1995
Ilse Kern, V. Steimle, C. Siegrist, B. Mach   +3 more
semanticscholar   +1 more source

Contribution of Gli1+ Adventitial Stem Cells to Smooth Muscle Cells in Atherosclerosis and Vascular Injury

Advanced Science, EarlyView.
Gli1+ adventitial stem cells (ASCs) have been thought to generate smooth muscle cells (SMCs) in atherosclerosis. Using a dual‐recombinase lineage tracing to exclude ectopic labeling, Wang et al. found that Gli1+ ASCs do not contribute to SMCs in atherosclerotic plaques.
Haixiao Wang, Xiuzhen Huang, Jialing Mou, Enci Wang, Yan Li, Wenjuan Pu, Yao Xie, Xiaoling Guo, Lixin Wang, Maoping Chu, Bin Zhou, Chao Niu   +11 more
wiley   +1 more source

AutoEpiCollect 2.0: A Web-Based Machine Learning Tool for Personalized Peptide Cancer Vaccine Design. [PDF]

Molecules
Kim CA, Shelton N, Samudrala M, Savsani K, Dakshanamurthy S.   +4 more
europepmc   +1 more source

Constitutive Expression of MHC Class II Genes in Melanoma Cell Lines Results from the Transcription of Class II Transactivator Abnormally Initiated from Its B Cell-Specific Promoter1

Journal of Immunology, 2001
Virginie Deffrennes, J. Vedrenne, M. Stolzenberg, J. Piskurich, G. Barbieri, J. Ting, D. Charron, C. Alcaïde-Loridan   +7 more
semanticscholar   +1 more source

⁠Engineering Adaptive Immunity in 3D: A Patient‐Specific Lymphoid Model Using Stromal Networks and Peripheral Blood Mononuclear Cells

Advanced Science, EarlyView.
This study presents a 3D lymphoid tissue model engineered from adipose‐derived stem cells differentiated into fibroblastic reticular cell–like networks and co‐cultured with immune cells. The engineered system successfully generates antigen‐specific antibodies and cytokine responses, providing a platform for studying adaptive immunity, vaccine efficacy,
Mei ElGindi, Shaza Karaman, Jeremy Teo
wiley   +1 more source

MHC Class II and Beyond: Complex Role of CD74 in Cancer. [PDF]

Cells
Bandola-Simon J, Roche PA.
europepmc   +1 more source

Surface‐Associated Proteins on Extracellular Vesicles Remodel the Tumor Microenvironment by Potentiating TGF‐β Signaling in a Contact‐Dependent Manner

Advanced Science, EarlyView.
Extracellular vesicles (EVs) released from TGF‐β‐activated CAFs are enriched with ECM proteins such as TSG6 and THBS1, which facilitate their binding to recipient cell membranes. This EV–cell interaction promotes the clustering of CD44 and TGF‐β receptors on the target cell surface, thereby potentiating TGF‐β signaling activity. This study highlights a
Chao Li, Agustin Enciso‐Martinez, Lizhe Zhu, Sarah A. Rotman, Peter A. van Veelen, Roman I. Koning, Hailiang Mei, Peter ten Dijke   +7 more
wiley   +1 more source

Enhanced MHC Class-II Expression in Fibroblastic Reticular Cells Associates with Maturation. [PDF]

Eur J Immunol
Roet JEG, da Graça CG, de Kok M, Panocha D, Konijn T, Roest HP, van der Laan LJW, van Baarsen LGM, de Winde CM, Mebius RE.   +9 more
europepmc   +1 more source

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao, Jing Yu, Xin Wang, Xu Liu, Fengli Zuo, Tianyue Xu, Leyi Tang, Ling Xiong, Li Li, Huifang Li, Xiaoting Chen, Guang Yang, Jing Jing, Xiaowei Liu   +13 more
wiley   +1 more source

Clustering-based identification of immune-related gene signatures in hepatocellular carcinoma. [PDF]

Ecancermedicalscience
Brahmaiah J, Adiga U, Augustine AJ, Vasishta S.   +3 more
europepmc   +1 more source