Results 191 to 200 of about 520,866 (339)

Plants, plant‐derived compounds, probiotics, and postbiotics as green agents to fight against poultry coccidiosis: A review

Animal Research and One Health, EarlyView.
Therapeutic effect of natural products on chicken coccidiosis. Abstract The intestinal tract is the main place for animals to digest food and absorb nutrients, which also serves as the first line of defense against pathogens that invade the internal environment.
Pan Chen, Kaili Liu, Taojing Yue, Yanan Lu, Senyang Li, Fuchun Jian, Shucheng Huang   +6 more
wiley   +1 more source

Genetic susceptibility to sarcoid in Arabian horses: associations with MHC class II and compound MHC class I/KLRA genotypes. [PDF]

Vet Res Commun
Vychodilova L, Plasil M, Futas J, Kopecka A, Molinkova D, Wijacki T, Jahn P, Knoll A, Horin P.   +8 more
europepmc   +1 more source

Association of Synovial Innate Immune Exhaustion With Worse Pain in Knee Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective Uncontrolled pain remains a major clinical challenge in the management of knee osteoarthritis (OA), the most common disabling joint disease. Worse pain is associated with synovial innate immune cell infiltration (synovitis), but the role of innate immune‐regulatory cells in pain is unknown. Our objective was to identify synovial innate immune
Holly T. Philpott, Trevor B. Birmingham, Garth Blackler, J. Daniel Klapak, Alexander J. Knights, Easton C. Farrell, Benoit Fiset, Logan A. Walsh, J. Robert Giffin, Edward M. Vasarhelyi, Steven J. MacDonald, Brent A. Lanting, Tristan Maerz, C. Thomas Appleton, on behalf of the WOREO Knee Study Group   +14 more
wiley   +1 more source

Genome-wide diversity and MHC characterisation in a critically endangered freshwater turtle susceptible to disease. [PDF]

Immunogenetics
Nelson HV, Silver L, Kovacs TGL, McLennan EA, Georges A, DeGabriel JL, Hogg CJ, Belov K.   +7 more
europepmc   +1 more source

Multiple parasites mediate balancing selection at two MHC class II genes in the fossorial water vole: insights from multivariate analyses and population genetics

Journal of Evolutionary Biology, 2008
Charlotte Tollenaere, Josef Bryja, Maxime Galan, P. Cadet, Julie Deter, Y. Chaval, Karine Berthier, A. R. Salvador, L. Voutilainen, Juha Laakkonen, Juha Laakkonen, Heikki Henttonen, J. Cosson, Nathalie Charbonnel   +13 more
semanticscholar   +1 more source

Paradoxical Activation of Entheseal Myeloid Cells by JAK1 and TYK2 Inhibitors via IL10 Antagonism

Arthritis &Rheumatology, Accepted Article.
Background JAK inhibition (JAKi) is effective in seronegative spondyloarthropathy (SpA) spectrum disorders, but TYK2 inhibition failed in SpA spectrum ulcerative colitis, and tofacitinib showed minimal benefit in Crohn's Disease, which highlights the complex role for JAK‐STAT signaling in different inflammatory processes. In this study, we investigated
Sami Giryes, Chi Wong, Charlie Bridgewood, Mark Harland, Ala Altaie, Nicole McDermott, Kerem Abacar, Abhay Rao, Almas Khan, Tristan McMillan, Peter Loughenbery, Robert Dunsmuir, Vishal Borse, Tom Macleod, Dennis McGonagle   +14 more
wiley   +1 more source

A single-cell atlas of Schwannoma across genetic backgrounds and anatomic locations. [PDF]

Genome Med
Gonzalez Castro LN, Gavish A, Bussema L, Mount CW, Neftel C, Nomura M, Chiocca EA, Bi WL, Arnaout O, Barker FG, Brown JM, Jordan JT, Batchelor TT, Stemmer-Rachamimov A, Plotkin SR, Tirosh I, Suvà ML.   +16 more
europepmc   +1 more source

FGL‐1 Modulates Inter‐Organ Communication by Controlling T Cell Homeostasis during the Onset of Sjögren's Disease

Arthritis &Rheumatology, Accepted Article.
Objective Autoimmunity occurs due to the tactics between pathogenic and regulatory factors in systemic organs. Although inter‐organ communication has been demonstrated in various diseases, the effects of the crosstalk between the immune system and other organs on autoimmune disease is unknown.
Kunihiro Otsuka, Aya Ushio, Ruka Nagao, Shigefumi Matsuzawa, Rieko Arakaki, Kazuki Fukuta, Yasuhiro Mouri, Takaaki Tsunematsu, Naozumi Ishimaru   +8 more
wiley   +1 more source

Prognostic nutrition index reveals LAG3 in cytotoxic CD8+ T cells and MHC class II in gastric cancer cells. [PDF]

Cancer Immunol Immunother
Tsutsumi C, Ohuchida K, Imamura M, Tan B, Shimada Y, Son K, Kosai T, Katayama N, Mochida Y, Hayashida S, Iwamoto C, Torata N, Horioka K, Shindo K, Mizuuchi Y, Ikenaga N, Nakata K, Oda Y, Nakamura M.   +18 more
europepmc   +1 more source

Antitumor efficacy of intermittent low-dose erlotinib plus sulindac via MHC upregulation and remodeling of the immune cell niche. [PDF]

Int J Cancer
What's new? Novel immunomodulatory insights derived from experimental models and clinical samples reveal the cancer‐preventive potential of intermittent low‐dose erlotinib plus sulindac (ERL + SUL). This study shows that ERL + SUL treatment upregulates MHC class I and II expression and remodels the immune cell niche, with significant tumor suppression ...
Tripathi C, Tovar Perez JE, Kapoor S, Muhsin A, Dashwood WM, Demirhan Y, Demirhan M, Shapiro A, Mohammed A, Sei S, Thompson J, Zaheer M, Sinha KM, Brown PH, Savage MI, Vilar E, Rajendran P, Dashwood RH.   +17 more
europepmc   +2 more sources