Results 261 to 270 of about 520,866 (339)

Genital Crohn's disease in pediatrics and genetic associations

JPGN Reports, EarlyView.
Abstract Genital edema is a rare presentation of Crohn's disease (CD), also known as metastatic CD (MCD). This may precede, co‐occur with, or follow gastrointestinal symptoms and present a diagnostic challenge. We aimed to characterize the features, clinical courses, pathogenesis, and outcomes of patients with MCD to increase understanding and promote ...
Erica Chang, Caroline Chinchilla Putzeys, Edward Hoffenberg, Ashish Patel, Elizabeth Hilow, Brad Pasternak   +5 more
wiley   +1 more source

Nobiletin restores the intestinal barrier of HFD-induced obese mice by promoting MHC-II expression and lipid metabolism. [PDF]

Mol Med
Yang N, Pang YS, Zheng Y, Gong YJ, Ding WJ.   +4 more
europepmc   +1 more source

IL-27 producers in a neonatal BCG vaccination model are a heterogenous population of myeloid cells that are diverse in phenotype and function. [PDF]

Immunohorizons
Divens AM, Ma L, Vance JK, Povroznik JM, Hu G, Robinson CM.   +5 more
europepmc   +1 more source

Exploring the dynamic landscape of immunopeptidomics: Unravelling posttranslational modifications and navigating bioinformatics terrain

Mass Spectrometry Reviews, EarlyView.
Abstract Immunopeptidomics is becoming an increasingly important field of study. The capability to identify immunopeptides with pivotal roles in the human immune system is essential to shift the current curative medicine towards personalized medicine. Throughout the years, the field has matured, giving insight into the current pitfalls. Nowadays, it is
Daniel Flender, Frédérique Vilenne, Charlotte Adams, Kurt Boonen, Dirk Valkenborg, Geert Baggerman   +5 more
wiley   +1 more source

The 2024 IPD-MHC database update: a comprehensive resource for major histocompatibility complex studies. [PDF]

Nucleic Acids Res
Maccari G, Robinson J, Barker DJ, Yates AD, Hammond JA, Marsh SGE.   +5 more
europepmc   +1 more source

Systematic Investigation of Tumor Microenvironment and Antitumor Immunity With IOBR

Med Research, EarlyView.
ABSTRACT The tumor microenvironment (TME) is a critical factor in antitumor immunity and treatment outcome in cancer therapy. We have developed an analysis tool called the immuno‐oncology biological research (IOBR) to investigate the TME and its role in antitumor immunity.
Yiran Fang, Yuyun Kong, Guangda Rong, Qingcong Luo, Wangjun Liao, Dongqiang Zeng   +5 more
wiley   +1 more source

Antitumor CD4+ T Helper 1 Cells Target and Control the Outgrowth of Disseminated Cancer Cells. [PDF]

Cancer Immunol Res
Ramamoorthi G, Lee MC, Farrell CM, Snyder C, Garg SK, Aldrich AL, Lok V, Dominguez-Viqueira W, Olson-Mcpeek SK, Rosa M, Gautam N, Pilon-Thomas S, Cen L, Kodumudi KN, Wiener D, Oskarsson T, Gomes AP, Gatenby RA, Czerniecki BJ.   +18 more
europepmc   +1 more source

Optimized Dynamic Network Biomarker Deciphers a High‐Resolution Heterogeneity Within Thyroid Cancer Molecular Subtypes

Med Research, EarlyView.
An optimized dynamic network biomarker approach reveals a critical transition signal and identifies three distinct molecular subtypes of differentiated thyroid cancer, each with unique global regulatory landscapes. ABSTRACT The progression of differentiated thyroid carcinoma (DTC) poses significant clinical challenges, especially in determining the ...
Haonan Zhang, Ge Zhang, Pengyuan Xu, Fengyi Yu, Liwen Li, Runzhi Huang, Pengpeng Zhang, Kaisaierjiang Kadier, Yuanyuan Wang, Qiqi Gu, Yalei Ding, Tianshu Gu, Hao Chi, Shiqian Zhang, Ruhao Wu, Yudi Xu, Shanshan Zhu, Honglin Zheng, Taiqi Zhao, Qi He, Xinguang Qiu   +20 more
wiley   +1 more source

Network-based multi-class classifier to identify optimized gene networks for acute leukemia cell line classification. [PDF]

PLoS One
Park H, Miyano S.
europepmc   +1 more source

Heterogeneity of Intratumoral Microbiota Within the Tumor Microenvironment and Relationship to Tumor Development

Med Research, EarlyView.
Mutual shaping of tumor microbiota and TME. Intratumoral microbiota—comprising diverse bacteria, fungi, viruses, and intracellular organisms—play critical and dynamic roles in shaping the tumor microenvironment (TME). Their spatial and compositional diversity contributes to both intratumoral and intertumoral heterogeneity, influencing immune modulation
Zhifei Gao, Aimin Jiang, Zizhuo Li, Lingxuan Zhu, Weiming Mou, Weitao Shen, Peng Luo, Bufu Tang, Jian Zhang, Anqi Lin   +9 more
wiley   +1 more source