Results 241 to 250 of about 162,844 (305)

Substrate Characterization of Mycobacterial Kinase PknG Revealing PknG‐KARS‐MAPK Phosphorylation Signaling Axis in Host

open access: yesiMetaMed, EarlyView.
This study employed multi‐omics approaches to investigate the regulatory mechanism of Mycobacterium PknG on host cell processes. We found that host lysine‐tRNA ligase (KARS) is a potential substrate of PknG; and PknG can regulate the immune response by catalyzing the phosphorylation of KARS at T592 and T595 sites, affecting the phosphorylation level in
Nana Tian   +13 more
wiley   +1 more source

Spatial multi‐omics identifies a NOTCH3‐mediated capillary–mCAF crosstalk driving immune exclusion in hepatocellular carcinoma

open access: yesiMeta, EarlyView.
Spatial multi‐omics defines a DLL4–NOTCH3–driven capillary–mCAF axis orchestrating fibrotic remodeling and immune exclusion in hepatocellular carcinoma tumor cores, conferring immune checkpoint blockade resistance. Targeting stromal NOTCH3 disrupts this pro‐fibrotic niche, enhances T cell infiltration, and synergizes with anti‐PD‐1 therapy ...
Fansen Ji   +18 more
wiley   +1 more source

Major Histocompatibility Complex Immunogenetic Diversity Differs Substantially Across Sea Turtle Species and Genomic Regions. [PDF]

open access: yesGenome Biol Evol
Martin KR   +9 more
europepmc   +1 more source

Acute Inflammation Drives Corneal Pathological Regeneration. [PDF]

open access: yesInvest Ophthalmol Vis Sci
Han Z   +10 more
europepmc   +1 more source

Enterococcus faecalis induces MHC-II expression by the intestinal epithelium during murine graft-versus-host disease.

open access: yesBlood
Nguyen CL   +21 more
europepmc   +1 more source

Vasculitic fasciitis characterizes a distinct subset of vasculitic myopathy with interferon-gamma signature. [PDF]

open access: yesActa Neuropathol
Ruffer N   +22 more
europepmc   +1 more source

Association of MHC class II β domain polymorphism in channel catfish (Ictalurus punctatus) with natural infection by Ligictaluridus floridanus. [PDF]

open access: yesParasitol Res
Roldán GMG   +5 more
europepmc   +1 more source

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