Results 231 to 240 of about 162,844 (305)

AI-powered mapping of tumor immunity for optimized mRNA vaccine engineering. [PDF]

Front Oncol
Srivastava R.
europepmc   +1 more source

Tumor Infiltrating Lymphocyte Therapy Combined With PD‐1/LAG‐3 Inhibition in Patients With Recurrent Platinum‐Resistant Ovarian Cancer

International Journal of Cancer, EarlyView.
The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg, Cathrine L. Lorentzen, Marie C. W. Westergaard, Trine Z. Iversen, Troels H. Borch, Marco Donia, Sigrid M. Mannering, Stine E. W. Banke, Özcan Met, Inge Marie Svane   +9 more
wiley   +1 more source

Epitope dynamics and antigenic shifts in dengue virus serotype 2 cosmopolitan genotype with structural changes in Bangladesh from 2017 to 2023. [PDF]

Sci Rep
Alam S, Tony SR, Khair S, Punno HT, Begum MN, Rahman M.   +5 more
europepmc   +1 more source

Genetic association between DLA class II and Symmetrical lupoid onychodystrophy in giant schnauzer and bearded collie [PDF]

, 2010
Harlos, Charlotte
core   +1 more source

Mental Health Conditions and Incident Cancer: A Prospective Cohort Study of 402,255 UK Biobank Participants

International Journal of Cancer, EarlyView.
Evidence suggests a potential association between mental health conditions and cancer risk, yet previous studies were limited by small samples and the use of self‐reported measures. Using data from the UK Biobank's large‐scale prospective population cohort over a median follow‐up of 13.4 years, this analysis demonstrates associations between depression,
Mohammed Sherif Amin, Solange Parra‐Soto, Ziyi Zhou, Shinya Nakada, Ike Dhiah Rochmawati, Carlos Celis‐Morales, Nancy Meligy, Jill P. Pell, Frederick K. Ho   +8 more
wiley   +1 more source

Promoting APC function of B cells via reprogramming the fatty acid metabolism enhances anticancer immunity in metastatic ovarian cancer. [PDF]

Cancer Immunol Immunother
Zhang H, Yu C, Du W, Li H, Liu Z, Li X, Yue Y, Wang B, Wang H, Ouyang Y, Wu H, Feng X, Yu J, Liu Y, Ji B, Cai S, Zhang H, Deng W.   +17 more
europepmc   +1 more source

Antibiotic Remodeling of the Gut Microbiota Impairs Host Resistance to Secondary Infection

iMetaMed, EarlyView.
Gut microbial dynamics induced by four antibiotics, revealed distinct taxonomic and functional shifts. Vancomycin‐perturbed bacteriomes were proven to promote pathogen resistance to antibiotic treatment. Metronidazole‐treated mice showed pronounced Salmonella translocation to hepatic tissue, and altered Enterococcus avium populations modulated host ...
Miaoyu Li, Ying Chen, Xi Chen, Weili Lu, Jie Liao, Jiaqi Wang, Qiwei Liu, Yanzi Chang, Zeping Xu, Yanye Tu, Yang Zhou, Jing Xue, Binbin Wang, Kang Chen, Keyun Cheng, Chunlai Zeng, Hong Li, Qing Shen   +17 more
wiley   +1 more source

HLA Class II Protein Expression Regulation Is Strongly Linked to Cis-Acting SNPs. [PDF]

HLA
Vince N, Ramsuran V, Viard M, Martinson J, Wolinsky S, Hussain S, Seaberg EC, Brown TT, Spence N, Thio CL, Goedert JJ, Hoots WK, Kirk GD, Carrington M.   +13 more
europepmc   +1 more source

bacNeo: A Computational Toolkit for Identifying Bacteria‐Derived Neoantigens in Human Cancers

iMetaMed, EarlyView.
We present bacterial neoantigen (bacNeo), a multi‐omics‐based computational software to classify bacterial components (BACC), type bacteria‐bound HLA alleles (BACH), and prioritize bacterial peptides as neoantigens (BACP). Bacterial neoantigen potential is quantified by score for peptide antigenicity recognition & kinetics (SPARK), enabling ...
Yunzhe Wang, Li Yuan, Katie W. Gu, Xiangdong Cheng, Bo Wen, Zhao Zhang   +5 more
wiley   +1 more source