Results 101 to 110 of about 47,345 (308)
Genetic alterations of chromosomes, p53 and p16 genes in low- and high-grade bladder cancer
, 2014 A majority of patients with bladder cancer present with superficial disease and subsequently, some patients show progression to muscle invasive or metastatic disease.
Demirhan O. +6 more
core +1 more source
CDKN2a (cyclin dependent kinase 2a / p16) [PDF]
, 2008 Review on CDKN2a (cyclin dependent kinase 2a / p16), with data on DNA, on the protein encoded, and where the gene is ...
Lemoine, A, Debuire, B, Saffroy, R
core +1 more source
Carrier‐free self‐assembled nanomedicine for combination‐therapy of acute myeloid leukemia
BMEMat, EarlyView.CPDS combines drugs with three different mechanisms of action to achieve a multi‐mechanism combination therapy for AML by directly killing tumor cells and activating anti‐tumor immunity. Abstract As the main acute myeloid leukemia (AML) clinical treatment, the chemotherapy alone cannot meet the clinical therapeutic needs due to the high heterogeneity ...
Meihong Chai +14 more
wiley +1 more source
Journal of Global Oncology, 2018 Purpose: Accurate detection of human papillomavirus (HPV) in oral cavity squamous cell carcinoma (OSCC) is essential to understanding the role of HPV in disease prognosis and management of patients.
Vinayak Palve +10 more
doaj +1 more source
Aberrant promoter hypermethylation of p16 gene in endometrial carcinoma
Tumor Biology, 2015 Previous studies demonstrated that the loss of function of the p16INK4A gene is mainly caused by the hypermethylation of p16 gene promoter; however, whether or not it is associated with the incidence of endometrial carcinoma (EC) remains unclear.
Zhuo-ying, Hu +4 more
openaire +2 more sources
Elaborating the Motivations and Attitudes Driving Interest in Voluntary Biodiversity Credits
Business Strategy and the Environment, EarlyView.ABSTRACT Global biodiversity loss has prompted the search for new sources of conservation finance, such as voluntary biodiversity credits (VBCs). However, despite optimistic market projections, current uptake of VBCs is limited. Adopting an interpretive approach, we analyse 21 semistructured interviews with early market actors (buyers, sellers ...
Gamze Yakar‐Pritchard +5 more
wiley +1 more source
Acta Médica Portuguesa, 2010 The genetic and epigenetic alterations are being studied as one of the causes of gastric cancer (GC) progression and development. DNA methylation is an epigenetic alteration which leads to suppressor gene silencing and proto-oncogene activation, playing ...
Maria Silva +7 more
doaj +1 more source
, 2003 Object. Several genes have been shown to carry mutations in human malignant gliomas, including the phosphatase and tensin homolog (PTEN) deleted on chromosome 10 and p16 tumor suppressor genes.
Zainuddin, Norafiza +9 more
core +1 more source
A Survival Epidemiology Framework for Oral and Oropharyngeal Cancer
Cancer Nexus, EarlyView.ABSTRACT Oral and oropharyngeal cancer remains a major global public health burden, but the literature addressing this disease is still organized predominantly around who develops it rather than around what determines life after diagnosis. That imbalance is consequential because diagnosis initiates a new scientific problem.
Raphael E. Cuomo
wiley +1 more source
Cloning and characterization of murine p16(INK4a) and p15(INK4b) genes
, 1995 Progression through the G1 phase of the cell cycle is regulated in part by the D-type cyclin-dependent kinases, cdk4 and cdk6. Genes encoding two specific inhibitors of these kinases, human p16((INK4a/MTS1)) and p15((INK4b/MTS2)) map to a region of ...
Quelle, D. E. +9 more
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