Results 171 to 180 of about 2,142,199 (296)

Understanding exosomes in facial esthetics and skin aging

Periodontology 2000, EarlyView.
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron, Catherine Davies, Anton Sculean, Paras Ahmad   +3 more
wiley   +1 more source

Integrative network toxicology and pharmacology reveal that kaempferol alleviates BaP-triggered pulmonary fibrosis via suppressing Ras/COX-2-dependent cellular senescence. [PDF]

Front Pharmacol
Zhao Q, Zhu D, Wu Z, Xia X, Li Y, Guo A, Xu Y, Zhou X.   +7 more
europepmc   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Development and External Evaluation of Hypoxia-Related Prognostic Signatures in Head and Neck Squamous Cell Carcinoma. [PDF]

Genes (Basel)
Osei JC, Aziz A, Smith TAD.
europepmc   +1 more source

A phase 1 study of 4'-thio-2'-deoxycytidine in patients with solid tumors. [PDF]

Cancer Chemother Pharmacol
O'Sullivan Coyne G, Kummar S, Rubinstein L, Anderson L, Hill K, Bruns A, Moore N, Ferry-Galow KV, Miller B, Wang L, Covey JM, Piekarz RL, Kuhlmann L, Miller SB, Juwara L, Collins J, Kinders RJ, Parchment RE, Chen AP, Doroshow JH.   +19 more
europepmc   +1 more source

BCMA Antigen Loss Through Acquired TNFRSF17 Deletion in Multiple Myeloma

International Journal of Laboratory Hematology, EarlyView.
Ali Benaboud, Rémi Tilmont, Gauthier Decool, Nicolas Gower, Salomon Manier, Benjamin Podvin   +5 more
wiley   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

[Corrigendum] The interaction between miR‑148a and DNMT1 suppresses cell migration and invasion by reactivating tumor suppressor genes in pancreatic cancer. [PDF]

Oncol Rep
Hong L, Sun G, Peng L, Tu Y, Wan Z, Xiong H, Li Y, Xiao W.   +7 more
europepmc   +1 more source

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

Bazi Bushen Attenuates Skeletal Muscle Decline Associated With Oestrogen Deficiency and Modulates FGFR1/ERK Signalling. [PDF]

J Cell Mol Med
Huang D, Xu N, Chu Q, Jia Z, Wang Y, Xu J.   +5 more
europepmc   +1 more source