Results 221 to 230 of about 7,394,141 (337)
ABSTRACT Background Healthcare professionals (HCPs) tend to display similar levels of implicit bias towards certain groups as the general population. This is concerning as such biases are known to result in poorer clinical decision‐making and therapeutic outcomes for offender populations.
Johan Jacobus Maasz +3 more
wiley +1 more source
Promoter methylation status of the tumor suppressor genes p16 and cadherin 1 in cervical intraepithelial neoplasia. [PDF]
Li RN, Li CY, Lee CH, Peng CY, Wu MT.
europepmc +1 more source
Hippo pathway disruption and YAP1 activation in anogenital papillary squamous intraepithelial lesion
Disruption of the Hippo Pathway with YAP1 activation is a consistent finding in papillary squamous intraepithelial lesions and may underlie their altered epithelial maturation and HPV E6/E7 expression patterns, providing new insight into the pathogenesis of this distinct low‐risk HPV‐associated lesion.
Gloria Zhang +4 more
wiley +1 more source
Endothelial Matrin‐3 suppresses cellular senescence and protects against atherosclerosis. Matrin‐3 deficiency induces endothelial senescence, mitochondrial dysfunction, and activation of p53‐, cell cycle‐, and senescence‐related pathways. In atherosclerosis‐prone mice, endothelial Matrin‐3 deletion promotes atherosclerotic lesion formation and disrupts
Xiao Cheng +5 more
wiley +1 more source
High‐risk human papillomavirus (hrHPV) testing improves cervical cancer screening by facilitating earlier detection and prevention. In low‐resource settings, however, cost and increased referrals limit its use. At the same time, many new and more affordable assays lack validation.
Neerja Bhatla +28 more
wiley +1 more source
CD47 is a regulator in doxorubicin-induced cardiac aging in male mice. [PDF]
Yan A +5 more
europepmc +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Punicalagin alleviates senile osteoporosis by inhibiting the senescence of bone mesenchymal stem cells via NRF2/HO-1 pathway. [PDF]
Wang Y +8 more
europepmc +1 more source
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao +10 more
wiley +1 more source

