Results 201 to 210 of about 7,394,141 (337)

Aquaporin‐4 Orchestrates Muscle Cell Differentiation and Satellite Cell Preservation: A Novel Target in Age‐Related Muscle Decline

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 6, December 2026.
ABSTRACT Background Impaired muscle regeneration is a key contributor to age‐related muscle decline, yet the molecular mechanisms linking muscle water homeostasis to regenerative failure remain incompletely understood. Aquaporin‐4 (AQP4), a major skeletal muscle water channel, may have functions beyond water transport that are relevant to muscle ...
María D. Girón, Manuel Manzano, Suzette L. Pereira, Antonio Reinoso, Chiara Burgio, Nora Montero‐Martin, Guillermo Jiménez‐Jiménez, Josep M. Argilés, Ricardo Rueda, José M. López‐Pedrosa, Rafael Salto   +10 more
wiley   +1 more source

[Corrigendum] Adjudin delays cellular senescence through Sirt3‑mediated attenuation of ROS production. [PDF]

Int J Mol Med
Geng K, Fu N, Yang X, Xia W.
europepmc   +1 more source

Promoter methylation of p16, DAPK, CDH1, and TIMP‐3 genes in cervical cancer: correlation with clinicopathologic characteristics

International Journal of Gynecological Cancer, 2006
D. Jeong, M. Youm, Young Nam Kim, Kyung Yol Lee, M. Sung, H. Yoon, Ki Tae Kim   +6 more
semanticscholar   +1 more source

Aphid Resistance in Pulse Crops: Sources, Mechanisms, Genetics and Breeding

Legume Science, Volume 8, Issue 4, December 2026.
ABSTRACT Aphids are major pests of pulse crops, causing damage through phloem sap feeding and virus transmission. In this context, resistant varieties are central components of sustainable aphid management. This review synthesizes current knowledge on resistance sources, phenotyping strategies, resistance mechanisms, genetic control and breeding ...
Francisco A. Mendes, Susana T. Leitão, Diego Rubiales, Maria Carlota Vaz Patto   +3 more
wiley   +1 more source

Dioscin attenuates D‑galactose‑induced retinal pigment epithelium senescence and epithelial-mesenchymal transition via the TGF‑β2/PI3K/Akt/β‑catenin pathway. [PDF]

PLoS One
Ouyang Q, Zhou H, Ji C, Jiang H, Zhao L, Pan Y, Xiang S, Hu X.   +7 more
europepmc   +1 more source

The loss of p16 expression in pancreatic carcinoma compared with p16 gene abnormalities

Japan Journal of Molecular Tumor Marker Research, 2000
Ohtsubo, Koushiro, Watanabe, Hiroyuki, Motoo, Yoshiharu, Okai, Takashi, Sawabu, Norio, Yasuyuki Asada, and   +5 more
openaire   +1 more source

An Investigation of Sleep Macro‐ and Microarchitecture by APOE Genotype

Annals of Neurology, Volume 100, Issue 5, Page 1012-1022, November 2026.
Objectives Apolipoprotein E ε4 (APOE ε4), a robust genetic risk factor for Alzheimer's disease (AD) is associated with functional connectivity deficits and amyloid pathology in brain regions involved in sleep regulation. Thus, alterations in sleep architecture may be one pathway through which ε4 contributes to Alzheimer's disease vulnerability. However,
Gawon Cho, Anne Chen, Eunyoung Choi, Orfeu M. Buxton, Daniel Kay, Adam Mecca, Brienne Miner   +6 more
wiley   +1 more source

Aurora kinase a phosphorylates and stabilizes UHRF1 to maintain DNA methylation and prostate cancer cell survival. [PDF]

Epigenetics
Xiang Q, Peng Y, Ye Y, Li X.
europepmc   +1 more source

High-throughput phenotypic screening identifies the phytochemical melissic acid that mitigates SHED cellular senescence via the ADCY5/cAMP/CREB axis. [PDF]

Front Pharmacol
Yang K, Liu L, Li C, Deng S, Cao J, Chen J, Wang S, Chen Q, Chen P.   +8 more
europepmc   +1 more source

Preanalytical variables affect predictive immunohistochemical biomarker testing in non–small cell lung carcinoma cytology specimens

Cancer Cytopathology, Volume 134, Issue 11, November 2026.
Abstract Background Several therapeutic targets for non–small cell lung carcinoma (NSCLC) rely on protein expression by immunohistochemistry (IHC). Most biomarkers are validated on formalin‐fixed, paraffin‐embedded (FFPE) tissue; however, cytologic specimens, including cell blocks (CBs), that are subject to preanalytical variables are increasingly used.
Saroja Devi Geetha, Wei‐Lien Wang, Neda Kalhor, Sinchita Roy‐Chowdhuri   +3 more
wiley   +1 more source