Results 181 to 190 of about 7,394,141 (337)

Bone biology in aging periodontal and peri‐implant tissues

Periodontology 2000, EarlyView.
Abstract Background Periodontal disease is an age‐related chronic inflammatory condition leading to tooth loss. Dental implants are an option for replacement of lost teeth in older adults. However, age‐related changes to alveolar bone may have pathological implications for its role in supporting the dentition and dental implants.
Dalia Rasheed Issa, Giuseppe Intini, Daniel Clark   +2 more
wiley   +1 more source

Gene therapy for p16-overexpressing cells

Aging, 2018
openaire   +2 more sources

From senescence and inflammaging to systemic comorbidities: Drivers of aging‐associated periodontitis

Periodontology 2000, EarlyView.
Abstract Background Aging is accompanied by a chronic low‐grade inflammatory process, known as inflammaging, as well as immunosenescence, an age‐related decline and dysregulation of immune function, and cellular senescence, a process in which cells enter a state of irreversible growth arrest while actively releasing pro‐inflammatory factors.
James Cheng, Chew Tin Zar Aung, Samuel F. Suslavich, Sinem Esra Sahingur, Yvonne L. Hernandez‐Kapila   +4 more
wiley   +1 more source

Insights Into the Interplay Between the Senescent Cells and Immune Cells. [PDF]

Aging Cell
Jaros M, Schmidt M, Neubert L, Kamp JC, von Vietinghoff S, Bräsen JH, Schmitt R, Melk A.   +7 more
europepmc   +1 more source

Molecular analysis of the cyclin‐dependent kinase inhibitor family: p16(CDKN2/MTS1/INK4A), p18(INK4C) and p27(Kip1) genes in neuroblastomas

Cancer, 1996
N. Kawamata, T. Seriu, H. Koeffler, C. Bartram   +3 more
semanticscholar   +1 more source

Understanding exosomes in facial esthetics and skin aging

Periodontology 2000, EarlyView.
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron, Catherine Davies, Anton Sculean, Paras Ahmad   +3 more
wiley   +1 more source

[Corrigendum] The interaction between miR‑148a and DNMT1 suppresses cell migration and invasion by reactivating tumor suppressor genes in pancreatic cancer. [PDF]

Oncol Rep
Hong L, Sun G, Peng L, Tu Y, Wan Z, Xiong H, Li Y, Xiao W.   +7 more
europepmc   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Public perspectives on potential changes to malaria deferral criteria in Canada

Vox Sanguinis, EarlyView.
Abstract Background and Objectives As blood collection agencies (BCAs) seek to increase donor diversity, making changes to eligibility criteria to enable more people to donate is an important consideration. BCAs in Canada have a permanent deferral from whole blood and platelet donation for anyone with a history of malaria, a barrier to donation for ...
Courtney Joshua, Carmen Charlton, Joelle Kasongo, Biba Tinga, Jennie Haw   +4 more
wiley   +1 more source

Prmt6 Deficiency Drives Osteoblast Senescence Promoting Age-Related Osteoporosis via Epigenetic Remodelling of the H3R2me2a/Sting/Ifitm3 Pathway. [PDF]

J Cell Mol Med
Wang Y, Ge X, Chang S, Wang D, Xu K, Xu H, Liu X, Wang S.   +7 more
europepmc   +1 more source