Results 191 to 200 of about 1,727,390 (297)

PD‐1 Inhibitor (Sintilimab) Combined With Chemotherapy as Neoadjuvant Therapy in Advanced Ovarian Cancer: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT In a patient with advanced ovarian cancer showing limited response to paclitaxel–carboplatin, adding sintilimab was associated with R0 cytoreduction and sustained disease‐free status during olaparib–bevacizumab maintenance. This case provides a rationale for further investigation of PD‐1 blockade as neoadjuvant therapy in carefully selected ...
Wang Zhenyan, Wang Yan
wiley   +1 more source

GDF15 participates in epithelial cell senescence in radiation-induced lung injury through the ERK1/2-p16 signaling pathway. [PDF]

PLoS One
Liu J, Lv D, Wang H, Yang D, Xu Y, Yan Y.   +5 more
europepmc   +1 more source

Advanced Primary Cervical Carcinosarcoma With Ovarian and Peritoneal Metastases in a Premenopausal Woman: A Rare Case Report From Northern Tanzania

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Cervical carcinosarcoma (CCS), also known as malignant mixed Müllerian tumor (MMMT) of the cervix, is an exceptionally rare and aggressive biphasic neoplasm composed of both epithelial and mesenchymal malignant components. Due to its rarity, optimal management strategies are not well established, particularly in low‐resource settings.
John Lugata, Gidion Kategugwa, Kimberly R. Sladek, Abitalis Mayengela, Kenneth Bagandanshwa, Baraka Shao, Edrick Elias, Joseph Mlay, Bariki Mchome, Eusebious Maro, Alex Mremi, Fredrick Mbise   +11 more
wiley   +1 more source

<i>P16</i> DNA Methylation Coupled with Somatic Copy Number Variations in the Development of Gastric Carcinomas. [PDF]

Cancers (Basel)
Yang Z, Zhou J, Deng L, Qiao J, Gu L, Deng D.   +5 more
europepmc   +1 more source

Craniofacial Morphology and Dental Age Assessment in Pediatric Craniosynostosis: A Comparative Cross‐Sectional Study

Clinical and Experimental Dental Research, Volume 12, Issue 5, October 2026.
ABSTRACT Objectives To delineate the craniofacial morphometric characteristics of Thai children with syndromic (SC) and non‐syndromic craniosynostosis (NSC) and to assess dental maturation relative to Chronological Age (CA). Methods This comparative cross‐sectional study evaluated 19 patients (SC: n = 13; NSC: n = 6; mean age 9.32 ± 2.67 years ...
Nutthakarn Ratanasereeprasert, Yanisa Wongbanthit, Narin Intarak, Preeya Suwanwitid, Chutimont Teekavanich, Anand Marya, Guang Hong, Thantrira Porntaveetus   +7 more
wiley   +1 more source

Nondiffuse p16 Expression in HPV-Associated and HPV-Independent Cervical Squamous Cell Carcinomas: A Single-Institution Case Series With Emphasis on Histopathologic Features and Molecular Alterations. [PDF]

Am J Surg Pathol
Shakiba D, Dobi A, Eugene HC, Nonogaki H, Numan TA, Wu TC, Xing D.   +6 more
europepmc   +1 more source

Promoter methylation status of the tumor suppressor genes p16 and cadherin 1 in cervical intraepithelial neoplasia. [PDF]

Oncol Lett, 2017
Li RN, Li CY, Lee CH, Peng CY, Wu MT.
europepmc   +1 more source

Factor VIII inhibitors demonstrate type I or type II kinetics in high‐titre alloantibodies and autoantibodies

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
The inhibitor kinetics type cannot be used by itself to determine auto‐ versus allo‐anti‐FVIII antibody type. To characterise inhibitor kinetics in inherited haemophilia A (HA) and acquired haemophilia A (AHA) patients in our centre, results show that inhibitors for both HA alloantibodies and AHA autoantibodies may exhibit either type I or type II ...
Cuicui Qiao, Jie Wang, Tiantian Wang, Hehe Wang, Yingfang Pan, Wei Liu, Yan Cheng, Feng Xue, Man‐Chiu Poon, Xinsheng Zhang, Yunhai Fang   +10 more
wiley   +1 more source

A spatial multi-omics atlas of immunosenescence reveals germinal-center B cell dysfunction in human lymph nodes. [PDF]

Cell Press Blue
Farzad N, Enninful A, Lu Y, Parisi F, Fung A, Kwon Y, Li Y, Labrosse M, Yang M, Strino F, Chen L, Yang J, Zhong M, Gao F, Tao B, Cunningham J, Bai Z, Li H, Wang F, Stankewich M, Kim D, Dong M, Bramer LM, Li K, Bhat MR, Loe E, Craft J, Pasa-Tolic L, Halene S, Shi L, Kluger Y, Xu ML, Fan R.   +32 more
europepmc   +1 more source

Refining the Multivariable Predictive‐Prognostic PREDICTR‐OPC Model for Survival in Surgical Escalation for Oropharyngeal Squamous Cell Carcinoma

The Laryngoscope, Volume 136, Issue 10, Page 4290-4300, October 2026.
The PREDICTR‐OPC model is the only prognostic classifier for oropharyngeal squamous cell carcinoma (OPSCC) that also predicts surgical outcomes. This study demonstrates that removing survivin from the model preserves its prognostic and predictive performance, with comparable discrimination, calibration, and clinical utility across training and ...
Lauren L. Zhang, Caroline Kristunas, C. Max Robinson, Jill M. Brooks, Alice J. Sitch, Stuart C. Winter, Justin Weir, Paul Matthews, Terry M. Jones, Keith Hunter, Pawel Golusinski, Ketan A. Shah, Selvam Thavaraj, Catharine M. West, Syed Haider, Edward Odell, Paul Nankivell, Sandra V. von Zeidler, Hisham Mehanna   +18 more
wiley   +1 more source