Results 211 to 220 of about 1,727,390 (297)

ELF3 promotes hyperglycemia-induced corneal epithelial senescence and IL-2 attenuates ELF3-associated signaling. [PDF]

Front Mol Biosci
Zhou S, Zhang H.
europepmc   +1 more source

Therapeutic Immune Reprogramming by Rapamycin Attenuates Plaque Inflammation and Lymphoid Immune Responses in Aged Atherosclerotic Mice

Aging Cell, Volume 25, Issue 10, October 2026.
Rapamycin exerts multifaceted immunomodulatory effects in age‐induced atherosclerosis, with pronounced inhibitory effects on adaptive immunity. Rapamycin reduced plaque inflammation and macrophage content, diminished pro‐inflammatory T cell responses, lowered age‐associated B cell frequencies, and attenuated senescence‐associated immune signatures ...
Jill de Mol, Daphne H. de Korte, Marie A. C. Depuydt, Virginia Smit, Mireia N. A. Bernabé Kleijn, Peter J. van Santbrink, Christoph J. Binder, Florentina Porsch, Frank H. Schaftenaar, Amanda C. Foks   +9 more
wiley   +1 more source

Ghrelin Alleviates Aging‐Related Cognitive Impairment by Regulating Autophagy‐Related Signaling via the SHBG/JNK1/Beclin1 Axis in Microglia

Aging Cell, Volume 25, Issue 10, October 2026.
This study found that aging‐related cognitive impairment is accompanied by hippocampal microglial senescence. Ghrelin suppresses microglial senescence by promoting autophagy through the SHBG/JNK1/Beclin1 axis, thereby alleviating aging‐related cognitive impairment. The graphical abstract was drawn using the Figdraw.
Lixing Zhou, Ying Cheng, Wanyu Zhao, Xuelian Sun, Fengjuan Hu, Meiling Ge, Yan Zhang, Gongchang Zhang, Birong Dong, Xiaolei Liu   +9 more
wiley   +1 more source

The Mechanistic Study of Melatonin Regulation of p16Ink4a and Oct4 in Anti-Cellular Senescence. [PDF]

J Cell Mol Med
Xu Y, Zhang C, Wang L, Chen X.
europepmc   +1 more source

Targeting YAP1-Mediated Tubular Cell Senescence to Attenuate Maladaptive Repair and Fibrotic Transition After Acute Kidney Injury. [PDF]

FASEB J
Zhao Z, An H, Sang Y, Chen S, Zhou J, Zhang T, Li J, Zhou X.   +7 more
europepmc   +1 more source

Cytogenetic Diversity of Variant Philadelphia Translocations in Chronic Myeloid Leukemia

International Journal of Laboratory Hematology, Volume 48, Issue 5, Page 1103-1112, October 2026.
ABSTRACT Introduction Chronic myeloid leukemia (CML) is a disease characterized by Philadelphia (Ph) translocations. These translocations can be classical or variant. The structural features and diagnostic implications of variant Philadelphia translocations remain incompletely defined, and they display considerable cytogenetic heterogeneity. Methods In
Ayse Gul Bayrak Tokac, Aynur Aday, Simge Erdem, Gulcin Bagatir, Burak Don, Ozden Ozcan, Akif Selim Yavuz, Sevgi Kalayoglu Besisik, Meliha Nalcaci, Kivanc Cefle, Sukru Ozturk   +10 more
wiley   +1 more source

Traditional Chinese Medicine Formulas in Delaying Aging: From Theoretical Foundations to Molecular Mechanisms and Translational Perspectives

Journal of Cellular and Molecular Medicine, Volume 30, Issue 19, October 2026.
ABSTRACT Aging is a systemic decline in physiological integrity, driving chronic diseases such as neurodegeneration, cardiovascular disorders, and metabolic syndromes. Rapid global population aging urgently demands effective interventions. Traditional Chinese medicine (TCM) formulas, characterized by multi‐component, multi‐target, and multi‐pathway ...
Chenrong Jin, Ding Du, Xiaorui Yu, Xiaoyan Ji, Xiuyun Zhang, Anning Li, Shuang Zu, Bo Qu, Daqing Zhao, Dianpeng Wu, Meichen Liu   +10 more
wiley   +1 more source

Bazi Bushen Capsule restores fertility by targeting mitochondrial health in aging endometrium. [PDF]

Imeta
Li S, Deng F, Niu H, Li M, Lin Z, Ma J, Wang Y, Leng Y, Hou Y, Cui W, Yu Y, Pan H, Zhou P, Li R.   +13 more
europepmc   +1 more source

Metastasis of Invasive Ductal Carcinoma of the Breast to the Uterine Cervix 30 Years Post‐Mastectomy: A Case Report

Journal of Obstetrics and Gynaecology Research, Volume 52, Issue 10, October 2026.
ABSTRACT Metastasis of invasive ductal carcinoma of the breast to the uterine cervix is rare, with only one report of a case occurring more than 20 years after the primary surgery. A 69‐year‐old woman presented with abnormal uterine cervical cytology (atypical glandular cells without tumor diathesis) 30 years after undergoing breast cancer surgery ...
Taro Miyake, Hidenori Sasa, Tsubasa Ito, Takanori Watanabe, Takako Sato, Sho Ogata, Masashi Takano   +6 more
wiley   +1 more source

Complete genome of marine flavobacterium <i>Dokdonia sp</i>. strain Dokd-P16 isolated from the low-iron waters of the subarctic Northeast Pacific Ocean. [PDF]

Microbiol Resour Announc
Alqattan A, Suttle CA, Maldonado MT.
europepmc   +1 more source