Results 171 to 180 of about 5,499,505 (307)

Spatial Profiling Identified Senescent Cancer-Associated Fibroblasts Localized in the Border Region of Human Pancreatic Ductal Adenocarcinoma. [PDF]

Cell Mol Gastroenterol Hepatol
Harada Y, Masuda A, Matsuura T, Nagata K, Nanno Y, Masamune A, Kodama Y, Hara E, Matsumoto T.   +8 more
europepmc   +1 more source

The loss of p16 expression in pancreatic carcinoma compared with p16 gene abnormalities

Japan Journal of Molecular Tumor Marker Research, 2000
Ohtsubo, Koushiro, Watanabe, Hiroyuki, Motoo, Yoshiharu, Okai, Takashi, Sawabu, Norio, Yasuyuki Asada, and   +5 more
openaire   +1 more source

Public perspectives on potential changes to malaria deferral criteria in Canada

Vox Sanguinis, EarlyView.
Abstract Background and Objectives As blood collection agencies (BCAs) seek to increase donor diversity, making changes to eligibility criteria to enable more people to donate is an important consideration. BCAs in Canada have a permanent deferral from whole blood and platelet donation for anyone with a history of malaria, a barrier to donation for ...
Courtney Joshua, Carmen Charlton, Joelle Kasongo, Biba Tinga, Jennie Haw   +4 more
wiley   +1 more source

JMJD3-driven epigenetic reprogramming of p16^INK4a-positive cells promotes tendon regeneration. [PDF]

Bone Res
Liu X, Lu W, Wang Y, Zhang P, Su Z, Cao T, Zhang Y, Zhao J, Wang J, Xiang H, Huang W, Wang K, Pang S, Chen M, Li Y, Liu S.   +15 more
europepmc   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

Polystyrene nanoplastics promotes inflammation and aging in young mice through the oral-gut microbiome axis. [PDF]

Front Immunol
Wang Y, Dong C, Xiao Y.
europepmc   +1 more source

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

Prevalence of heterozygous and homozygous 9p21 deletions in human cancer: a tissue microarray study on 4,999 tumors from 125 different tumor types. [PDF]

Mol Med
Gorbokon N, Teljuk K, Schraps N, Lennartz M, Rico SD, Kind S, Reiswich V, Viehweger F, Lutz F, Fraune C, Luebke AM, Menz A, Schlichter R, Krech T, Hinsch A, Burandt E, Sauter G, Simon R, Steurer S, Marx AH, Lebok P, Dum D, Minner S, Jacobsen F, Clauditz TS, Hackert T, Uzunoglu FG, Bernreuther C, Kluth M.   +28 more
europepmc   +1 more source

Survival of Patients with Glioblastoma Multiforme is not Influenced by Altered Expression of P16, P53, EGFR, MDM2 or Bcl‐2 Genes

Brain Pathology, 1998
E. Newcomb, H. Cohen, S. Lee, Sandhya K. Bhalla, Joanna Bloom, R. Hayes, Douglas C. Miller   +6 more
semanticscholar   +1 more source

Intrinsic pH chemosensitivity of acutely dissociated medullary serotonergic and retrotrapezoid neurones

The Journal of Physiology, EarlyView.
Abstract figure legend Central respiratory chemoreceptors (CRCs) are critical for maintaining normal systemic levels of pH and PCO2. A CRC must respond to pH via intrinsic mechanisms. Here we quantified intrinsic chemosensitivity of medullary 5‐HT neurones and retrotrapezoid nucleus (RTN) neurones using acute dissociation.
Yuanming Wu, Eduardo Bravo, George Bradley Richerson   +2 more
wiley   +1 more source