Results 191 to 200 of about 5,499,505 (307)

Understanding the Epigenetic Landscape of Barrett's Esophagus and Esophageal Cancer: A Review of Current Findings, Caveats and Future Directions

Genes, Chromosomes and Cancer, Volume 65, Issue 9, September 2026.
ABSTRACT Esophageal cancer (OC) is currently the eighth most common form of cancer worldwide with a 5‐year survival rate of 10%–20%, with the primary risk factor of esophageal adenocarcinoma (OAC) being the development of Barrett's Esophagus (BO).
Louise Lawless, Trevor Doherty, Carla Surlis, Niamh Gilmartin, Therese M. Murphy   +4 more
wiley   +1 more source

Tubular Omega-3 Fatty Acid Receptor FFAR4 Deficiency Aggravated Renal Aging and Chronic Kidney Disease. [PDF]

Aging Cell
Yang L, Tang L, Li J, Liu D, Hu C, Guo F, Lin L, Huang R, Fu P, Ma L.   +9 more
europepmc   +1 more source

Mutation analysis of the p53, APC, and p16 genes in the Barrett's oesophagus, dysplasia, and adenocarcinoma.

Journal of Clinical Pathology, 1997
María Verónica González, M. L. Artímez, L. Rodrigo, C. López-Larrea, M. Menéndez, V. Álvarez, R. Pérez, M. Fresno, M. Perez, A. Sampedro, E. Coto   +10 more
semanticscholar   +1 more source

Fisetin Attenuates Amyloid‐Beta‐Induced Neurotoxicity in Human Neuroblastoma SH‐SY5Y Cells: Integrating In Silico Target Prediction and In Vitro Validation

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
The in‐silico data showed that fisetin binds stably with the autophagy receptors and synaptic density regulators. Further, in‐vitro data confirmed the restoration of Aβ1‐42 disrupted autophagy by fisetin. Fisetin restored the oxidative stress and ion channels, along with a reduction of AChE activity.
Charu Jaiswal, Ishika Singh, Abhishek Kumar Singh   +2 more
wiley   +1 more source

Sauchinone attenuates UVB-induced photoaging by suppressing oxidative stress and ferroptosis through activation of the Keap1-Nrf2 pathway in dermal fibroblasts. [PDF]

Pharm Biol
Zhang X, Wang J, Zhou Y, Shen C, Yuan M, Li Q, Li W.   +6 more
europepmc   +1 more source

Frequent abnormalities of the p15 and p16 genes in mycosis fungoides and sezary syndrome.

Journal of Investigative Dermatology, 2002
J. Scarisbrick, A. Woolford, E. Calonje, A. Photiou, S. Ferreira, G. Orchard, R. Russell‐Jones, S. Whittaker   +7 more
semanticscholar   +1 more source

Advances in FGF/FGFR Signaling: Implications for Disease and Therapy

MedComm, Volume 7, Issue 9, September 2026.
The FGF/FGFR signaling is indispensable for the maintenance of physiological homeostasis and governs multiple biological processes, including embryonic development, bone metabolism, angiogenesis, and neurogenesis, whereas aberrant hyperactivation of this pathway drives the progression of malignancies and autoimmune disorders, including inflammatory ...
Miaoyu Song, Xi Liu, Yang Xiao, Yongsheng Li, Huakan Zhao   +4 more
wiley   +1 more source

Modulation of NF-κB and TLR Signaling Pathways and Complement Components in Ovine Maternal Thyroid During Early Pregnancy. [PDF]

Int J Mol Sci
Zhang Y, Li J, Yang F, Wu C, Zhang L, Yang L.   +5 more
europepmc   +1 more source

Histiocytosis development and clinical variation through the lens of genomics

The Journal of Pathology, Volume 270, Issue 1, Page 23-39, September 2026.
Abstract Histiocytic neoplasms are rare haematologic diseases characterised by clonal expansions of cells with a monocyte, macrophage or dendritic cell phenotype. Their clinical manifestations are diverse, ranging from indolent lesions to aggressive systemic disease.
Paul G Kemps, Astrid GS van Halteren, Tom van Wezel, Pancras CW Hogendoorn   +3 more
wiley   +1 more source

The SIRT1-p53 axis drives a ferro-aging-like program and aggravates trophoblast dysfunction in preeclampsia. [PDF]

Front Aging
Hu R, Chen Z, Bian W, Zhang J, Xu X, Xiong H, Xiang S, Ding Y, Qi H, Yang H.   +9 more
europepmc   +1 more source