Results 191 to 200 of about 47,513 (307)

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

Induced pluripotent stem cell-derived models of malignant nerve sheath tumor progression mimic glial to neuro-mesenchymal transition and uncover therapeutic opportunities. [PDF]

Nat Commun
Uriarte-Arrazola I, Magallón-Lorenz M, Fernández-Rodríguez J, Zhang J, Lee E, Ortega-Bertran S, Creus-Bachiller E, Farrés-Casas J, Wilson KM, McKnight C, Recabo K, Blanco I, Salvador H, Romagosa C, Lázaro C, Mazuelas H, Gel B, Ferrer M, Carrió M, Serra E.   +19 more
europepmc   +1 more source

Intrinsic pH chemosensitivity of acutely dissociated medullary serotonergic and retrotrapezoid neurones

The Journal of Physiology, EarlyView.
Abstract figure legend Central respiratory chemoreceptors (CRCs) are critical for maintaining normal systemic levels of pH and PCO2. A CRC must respond to pH via intrinsic mechanisms. Here we quantified intrinsic chemosensitivity of medullary 5‐HT neurones and retrotrapezoid nucleus (RTN) neurones using acute dissociation.
Yuanming Wu, Eduardo Bravo, George Bradley Richerson   +2 more
wiley   +1 more source

Regulation of Neuronal Senescence by <i>Srebf2</i> and <i>Zmiz1</i> Reveals Mechanisms of Aging-Related Neurodegeneration. [PDF]

Biology (Basel)
Deng Z, Chen J, Li J, Luo X, Luo Q, Ren M, Li X.   +6 more
europepmc   +1 more source

Deceptive Thyroid Pathologies: Anaplastic Thyroid Carcinoma Mimics and Clinical Implications

Head &Neck, Volume 48, Issue 8, Page 2180-2189, August 2026.
ABSTRACT Background Beyond follicular‐derived thyroid carcinomas, lymphomas, and metastatic disease, there are rare pathologies of the thyroid gland that represent a challenge. We report patients with unusual malignancies that mimic similar aggressive cancers. Methods Retrospective case series.
David Z. Allen, S. Mohsen Hosseini, Mark Zafereo, Miriam Lango, Elizabeth Gardner Grubbs, Priyanka Iyer, Shreyaskumar R. Patel, Vinod Ravi, Naifa Lamki Busaidy, Rui Jennifer Wang, Michelle D. Williams, Maria E. Cabanillas, Anastasios Maniakas   +12 more
wiley   +1 more source

Andrographolide attenuates microglial senescence in Alzheimer's disease mice by suppressing the STAT3 signaling. [PDF]

iScience
Song H, Yang M, Wu S, Dai Q, Qin W, Xie W, Chen Y, Jiang X, Zhang X, Deng X, Ouyang C, Zhang Y, Liu X, Zhu Y, Huang G.   +14 more
europepmc   +1 more source

A Critical Analysis of Secondary Victims' Preferred Method of Reporting Crime in a South African Township

Sexuality, Gender &Policy, Volume 9, Issue 3, August 2026.
ABSTRACT Digital communication has facilitated freedom of expression in various contexts worldwide. Digitalized communication is a form of expression that has become the norm worldwide despite cybercrime and other challenges. Communication preferences for social media determine attitudes to reporting crime.
Nomsa Ingrid Zikalala
wiley   +1 more source

The loss of p16 expression in pancreatic carcinoma compared with p16 gene abnormalities

Japan Journal of Molecular Tumor Marker Research, 2000
Ohtsubo, Koushiro, Watanabe, Hiroyuki, Motoo, Yoshiharu, Okai, Takashi, Sawabu, Norio, Yasuyuki Asada, and   +5 more
openaire   +1 more source

Divergent myeloid and lymphoid immune landscapes in HPV/p16 positive and HPV/p16 negative oropharyngeal squamous cell carcinomas and their lymph node metastases. [PDF]

Mol Med
Graessle R, Piwonski I, Franzen A, Olze H, Kühl AA, Hummel M, Erben U, Coordes A.   +7 more
europepmc   +1 more source

Targeting YAP1‐Mediated Tubular Cell Senescence to Attenuate Maladaptive Repair and Fibrotic Transition After Acute Kidney Injury

The FASEB Journal, Volume 40, Issue 13, 15 July 2026.
YAP1 mediates tubular cell senescence and drives maladaptive repair following AKI, promoting the AKI to CKD transition. Single‐cell RNA‐seq reveals sustained YAP1 overexpression, fibroblast activation, and pro‐fibrotic tubular cell shift. Senolytic agents or verteporfin (YAP1/TEAD1 inhibitor) suppress YAP1 activity, reduce renal senescence, alleviate ...
Zhibo Zhao, Huiping An, Yonghou Sang, Si Chen, Jinxiu Zhou, Tingting Zhang, Junhu Li, Xiaoshuang Zhou   +7 more
wiley   +1 more source