Results 201 to 210 of about 5,499,505 (307)

Knowledge gaps in tubular gut tumours: a critical appraisal of the 6th edition of the World Health Organization classification of tumours

The Journal of Pathology, Volume 270, Issue 1, Page 4-22, September 2026.
Abstract Gastrointestinal cancer is a global health problem. In the new 6th edition of the World Health Organization Classification of Tumours (WCT) of the Digestive System, updated evidence and guidance is provided for the aetiology, pathogenesis, diagnosis, classification, grading, staging and prognosis of these tumours.
Iris D Nagtegaal, Elizabeth A Montgomery, Alexandros D Polydorides, Anthony J Gill, Motohiro Kojima, Mark J Arends   +5 more
wiley   +1 more source

Andrographolide attenuates microglial senescence in Alzheimer's disease mice by suppressing the STAT3 signaling. [PDF]

iScience
Song H, Yang M, Wu S, Dai Q, Qin W, Xie W, Chen Y, Jiang X, Zhang X, Deng X, Ouyang C, Zhang Y, Liu X, Zhu Y, Huang G.   +14 more
europepmc   +1 more source

Industry perceptions of biological control in food manufacturing environments: A qualitative analysis of barriers and opportunities

Annals of Applied Biology, Volume 189, Issue 2, September 2026.
Biological control is widely used in agriculture but rarely deployed in food manufacturing, where industry acceptability is unexamined. Semi‐structured interviews with 17 food manufacturing professionals across 15 facility contexts in northwest England and north Wales explored views on entomopathogenic fungi, Bacillus thuringiensis and parasitoid wasps.
Bethany Hadfield, Ben J. Clunie, Tom W. Pope, Joe M. Roberts   +3 more
wiley   +1 more source

Age-associated miR-30e-3p upregulation drives ovarian follicular granulosa cell senescence by targeting DPY30 in laying hens. [PDF]

Poult Sci
Wei Y, Wang Y, Liao C, Cui C, Zhang Y, Li Z, Sun C, Zhu Q, Yin H.   +8 more
europepmc   +1 more source

A Mechanism‐Based Framework for Anti‐Aging Strategies: From Metabolic Regulation to Senotherapy and Stem Cell‐Based Interventions

Aging Cell, Volume 25, Issue 9, September 2026.
The aging of the human body is a complex process driven by multiple contributing factors. Based on their underlying mechanisms, current anti‐aging interventions can be classified into six primary categories. This paper summarizes the most promising anti‐aging strategies within each class. ABSTRACT The global prevalence of aging and age‐related diseases
Feifei Li, Yankai Wang, Gelin Wang, Jiguo Chen, Song Huang   +4 more
wiley   +1 more source

Deregulation of stemness and senescence genes in bone marrow mesenchymal stem cells of multiple myeloma: implications for therapeutic approaches. [PDF]

Blood Res
Soleymani F, Kavousi S, Khodakarim N, Ahmadvand M.   +3 more
europepmc   +1 more source

Surviving Fibroblasts After Treatment With Mitomycin C Exhibit SASP‐Like Phenotype After Glaucoma Filtration Surgery

Aging Cell, Volume 25, Issue 9, September 2026.
Transcriptomic analysis using a rabbit glaucoma filtration surgery model, combined with in vitro experiments on human conjunctival fibroblasts, demonstrates that mitomycin C induces a senescence‐associated secretory phenotype (SASP)‐like state. These SASP‐like fibroblasts were selectively eliminated by the specific senolytic agent, highlighting their ...
Akitoshi Kimura, Tomokazu Fujimoto, Satoshi Iraha, Kei‐Ichiro Yasunaga, Miyuki Inoue‐Mochita, Naofumi Funagura, Shunsuke Tanigawa, Daisuke Kurotaki, Tomoaki Koga, Fumika Watanabe‐Kitamura, Utako Tsutsumi‐Kuroda, Mitsuyoshi Nakao, Toshihiro Inoue   +12 more
wiley   +1 more source

Machine learning-driven multi-omics integration uncovers a senescence associated molecular axis in HCC. [PDF]

Front Immunol
Tuergan T, Abulaiti A, Yilihaer Y, Liu B, Shao Y, Jiang T, Aji T.   +6 more
europepmc   +1 more source

hTERT Immortalization Stabilizes Human Umbilical Cord MSCs and Maintains Their Small Extracellular Vesicles With Preserved Immunomodulatory Activity and Primordial Follicle‐Activating Capacity

Aging Cell, Volume 25, Issue 9, September 2026.
hTERT immortalization stabilizes hUCMSC‐derived sEV function by alleviating cellular senescence and preserving young‐like cargo profiles. H11‐sEVs retain immunomodulatory activity, primordial follicle‐activating capacity, and ovarian protective effects.
Yating Chen, Wei Liu, Ying Tian, Xinyu Wang, Haonan Fan, Mingyu Yang, Feiyang Diao, Jing Li   +7 more
wiley   +1 more source

Antioxidant and anti-senescence supramolecular complexes for managing dry eye diseases. [PDF]

Bioact Mater
Song X, Zhu J, Wang R, Yao Y, Zhou T, Dai W, He X, Jin Q, Yao K, Han H.   +9 more
europepmc   +1 more source