Results 181 to 190 of about 5,499,505 (307)

Induced pluripotent stem cell-derived models of malignant nerve sheath tumor progression mimic glial to neuro-mesenchymal transition and uncover therapeutic opportunities. [PDF]

Nat Commun
Uriarte-Arrazola I, Magallón-Lorenz M, Fernández-Rodríguez J, Zhang J, Lee E, Ortega-Bertran S, Creus-Bachiller E, Farrés-Casas J, Wilson KM, McKnight C, Recabo K, Blanco I, Salvador H, Romagosa C, Lázaro C, Mazuelas H, Gel B, Ferrer M, Carrió M, Serra E.   +19 more
europepmc   +1 more source

Clinical Validation of Four Point‐of‐Care High‐Risk HPV Assays, Including Two Reduced‐Valency Assays, for Cervical Cancer Screening in Low‐Resource Settings

International Journal of Cancer, Volume 159, Issue 8, Page 2004-2014, 15 October 2026.
High‐risk human papillomavirus (hrHPV) testing improves cervical cancer screening by facilitating earlier detection and prevention. In low‐resource settings, however, cost and increased referrals limit its use. At the same time, many new and more affordable assays lack validation.
Neerja Bhatla, MaryLuz Rol, Seema Singhal, Showket Hussain, Anushree Patil, Pranay Tanwar, Shalini Singh, Vikrant M. Bhor, Kiran Munne, Richa Vashishtha, Shachi Vashist, Eric Lucas, Richard Muwonge, Arianis Tatiana Ramírez, Anju Singh, Vikas Khan, Jyoti Rani, Nasera Firdausi, Sandeep Sisodiya, Rutuja Wakchaure, María Alejandra Picconi, Alejandro Calderón, Margo Bell, Annemie De Smet, Alex Vorsters, Gary M. Clifford, Madhavi Chandra, Jitendra Kumar, Partha Basu   +28 more
wiley   +1 more source

Automatic Conversion of NICE Guidelines to an Executable Computational Model Using Large Language Models

Learning Health Systems, Volume 10, Issue 4, October 2026.
ABSTRACT Introduction The UK National Institute for Health and Care Excellence (NICE) produce guidelines that provide evidence‐based recommendations to support clinical care across England and Wales, but remain available in unstructured natural language form.
Ashvin Gupta, Denys Prociuk, Alessandra Russo, Brendan C. Delaney   +3 more
wiley   +1 more source

Diminished and Altered Cellular Senescence Response in Delayed Wound Healing of Aging. [PDF]

Aging Cell
Shvedova M, Thanapaul RJRS, Wang Q, Shin GH, Dhillon J, Roh DS.   +5 more
europepmc   +1 more source

Among genes involved in the RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors

Oncogene, 1997
H. Kovar, G. Jug, D. Aryee, A. Zoubek, P. Ambros, B. Gruber, R. Windhager, H. Gadner   +7 more
semanticscholar   +1 more source

Synchronous Vaginal and Liver Metastases in Rectosigmoid Cancer: Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Vaginal metastasis from colorectal cancer is extremely rare. We report the case of a 58‐year‐old postmenopausal woman with rectosigmoid adenocarcinoma and synchronous liver and vaginal metastases who initially presented with gastrointestinal symptoms followed by vaginal bleeding.
Tamader Alyaarabi, Mahmood Al‐Dhaheri, Hamza A. Abdul‐Hafez, Ammar Aleter, Noof Al Naimi, Mohamed Kurer, Mohamed Abunada, Ali Toffaha   +7 more
wiley   +1 more source

Regulation of Neuronal Senescence by <i>Srebf2</i> and <i>Zmiz1</i> Reveals Mechanisms of Aging-Related Neurodegeneration. [PDF]

Biology (Basel)
Deng Z, Chen J, Li J, Luo X, Luo Q, Ren M, Li X.   +6 more
europepmc   +1 more source

Promoter methylation status of E-cadherin, hMLH1, and p16 genes in nonneoplastic gastric epithelia.

American Journal of Pathology, 2002
T. Waki, G. Tamura, T. Tsuchiya, Kiyoshi Sato, S. Nishizuka, T. Motoyama   +5 more
semanticscholar   +1 more source

Fucoxanthin Attenuates Hepatic Damage in a d‐Galactose‐Induced Accelerated Aging Mouse Model: Insight Into Underlying Mechanisms

Food Frontiers, Volume 7, Issue 5, September 2026.
Fucoxanthin alleviates d‐galactose‐induced hepatic damage by reducing oxidative stress, inflammation, and multiple programmed cell death pathways. ABSTRACT The global population is aging rapidly, and aging‐related hepatic damage poses a significant public health challenge.
Han‐Ni Wei, Cheng‐Yu Yang, Hui Li, Shi‐Xiang Wu, Qing‐Yan Zou, Yan Zheng, Kazuo Miyashita, Yu‐Hong Yang, Lei Du   +8 more
wiley   +1 more source

Divergent myeloid and lymphoid immune landscapes in HPV/p16 positive and HPV/p16 negative oropharyngeal squamous cell carcinomas and their lymph node metastases. [PDF]

Mol Med
Graessle R, Piwonski I, Franzen A, Olze H, Kühl AA, Hummel M, Erben U, Coordes A.   +7 more
europepmc   +1 more source