Results 241 to 250 of about 5,499,505 (307)

ZDHHC17‐Mediated CDK4 Palmitoylation Drives Cell Cycle Progression and Orchestrates Cancer Immune Surveillance

Advanced Science, Volume 13, Issue 44, 7 August 2026.
ZDHHC17 palmitoylates CDK4, which together with TRAF6‐mediated ubiquitination, drives cell cycle progression and immune surveillance, revealing a rational combination of CDK4 inhibitors with immune checkpoint blockers for ZDHHC17‐driven cancers. ABSTRACT Uncontrolled cell cycle progression is a hallmark of cancer, tightly regulated by both intrinsic ...
Zekang Wang, Peipei Song, Xueji Wu, Lei Wang, Wei Xie, Pinning Feng, Chao Cheng, Jianping Guo   +7 more
wiley   +1 more source

Multi-omics profiling reveals systemic rejuvenation of the aged kidney through senolytic therapy. [PDF]

NPJ Regen Med
Chen S, Zhang C, Cang P, Guo W, Xiao L, He Y, Su Q, Ouyang S, Zha J, Maimaitirexiati G, Chen Y, Qi X, He S, Zhang Q, Xu Y, Yang J, Fan G.   +16 more
europepmc   +1 more source

Alpha‐B‐crystallin immunohistochemistry: A sensitive but non‐specific marker for epileptogenic lesions

Brain Pathology, Volume 36, Issue 5, September 2026.
Ekin Güney, Ilay Caliskan, Tara Saunders, Mercedes Paredes, Calixto‐Hope Lucas, Kanish Mirchia, Rufei Lu, Merryl Terry, Erika Cagampan, Melike Pekmezci, Andrew Bollen, Arie Perry, Cathryn R. Cadwell, Tarık Tihan   +13 more
wiley   +1 more source

p21-Positive Senescent Stromal Cells Promote Prostate Cancer Immune Suppression and Progression That Can Be Reversed by Senolytic Therapy. [PDF]

Cancer Discov
Zhou L, DeMarco KD, Murphy KC, Wu Z, Li J, Johnson C, Liu B, Giwa HK, Ma B, Bhalerao N, Li J, Jiang Z, Bai S, Parikh CN, Ye T, Simin K, Zhu LJ, Pitarresi JR, Wu H, Ruscetti M.   +19 more
europepmc   +1 more source

Blood plasma and oral rinse liquid profiling for human papillomavirus in head and neck cancer - Unmasking false-positive p16 tissue cases and tracking disease dynamics. [PDF]

J Transl Med
Mack M, Roesch R, Rinecker J, Stögbauer F, Krippgans S, Nieberler M, Püchler K, Garcia-Perez C, Secci R, Jacob A, Pfarr N, Steiger K, Mogler C, Wollenberg B, Ruland J, Kerle IA, Wirth M, Winter C.   +17 more
europepmc   +1 more source

Double-Pronged NAD Preservation: Delaying Cellular Senescence and Initiating Musculoskeletal Regeneration. [PDF]

Aging Cell
Yu J, Hou M, Deng Y, Yu C, Liu Y, Kang K, Xia X, Li X, Yang H, Jiang D, Xu W, Zhang Y, Zhu X.   +12 more
europepmc   +1 more source

Identification of a 32-gene signature that determines HPV status in head and neck cancer. [PDF]

Discov Oncol
Zhou DS, Lu YQ.
europepmc   +1 more source

HK2-driven histone H3K18 lactylation promotes stromal cell senescence and decidualization deficiency in URSA via CUX1-mediated SASP factor transcription. [PDF]

Cell Mol Biol Lett
Zhao X, Zhao Y, Jiang Y, Ma Y, Ma J, Zhao H, Feng X.   +6 more
europepmc   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

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Loss of function of p16 gene and prognosis of pulmonary adenocarcinoma

Cancer, 2005
AbstractBACKGROUNDStepwise progression of peripheral‐type lung adenocarcinoma was characterized morphologically and was related to prognosis. Expression of the tumor suppressor gene p16 in pulmonary adenocarcinoma decreased, mainly as a result of aberrant methylation of the CpG islands of the promoter region.METHODSAberrant methylation status of the ...
Ryota, Tanaka, Daye, Wang, Yukio, Morishita, Yukinori, Inadome, Yuko, Minami, Tatsuo, Iijima, Shimao, Fukai, Tomoyuki, Goya, Masayuki, Noguchi   +8 more
openaire   +2 more sources