Double-Pronged NAD Preservation: Delaying Cellular Senescence and Initiating Musculoskeletal Regeneration. [PDF]
Yu J +12 more
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Combining bioinformatics and machine learning to analyze and validate sepsis-related cell senescence genes and potential drugs. [PDF]
Pei S +9 more
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Identification of a 32-gene signature that determines HPV status in head and neck cancer. [PDF]
Zhou DS, Lu YQ.
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HK2-driven histone H3K18 lactylation promotes stromal cell senescence and decidualization deficiency in URSA via CUX1-mediated SASP factor transcription. [PDF]
Zhao X +6 more
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Tomatidine is a senotherapeutic compound that improves cognitive function and reduces cellular senescence in aged mice. [PDF]
Costa DG +19 more
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Aged murine bone marrow myeloid and mesenchymal cells develop unique senescence phenotypes. [PDF]
Doolittle ML +7 more
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Deletion of the p16 and p15 Genes in Human Bladder Tumors
Two genes, p16 (also known as CDKN2, INK4A, or MTS1) and p15 (also described as INK4B or MTS2), are found in tandem at chromosome 9p21. These genes are designated as candidate tumor suppressor genes because they encode proteins that function as negative cell cycle regulators. (The encoded polypeptides inactivate specific cyclin-protein kinase complexes
I, Orlow +9 more
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Study on P16 gene in acute leukemia
Current Medical Science, 2000To study the change of suppressing cancer gene P16 in acute leukemia, the P16 antigen expression of leukemia cell surfaces in 61 cases were investigated with ABC assay and gene structural defects in 51 cases of acute leukemia were examined with multiple comparative PCR method.
Y, Chen, H, Zhang, B, Yue, H, Li
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