Results 251 to 260 of about 47,513 (307)

Double-Pronged NAD Preservation: Delaying Cellular Senescence and Initiating Musculoskeletal Regeneration. [PDF]

open access: yesAging Cell
Yu J   +12 more
europepmc   +1 more source

Tomatidine is a senotherapeutic compound that improves cognitive function and reduces cellular senescence in aged mice. [PDF]

open access: yesEMBO Mol Med
Costa DG   +19 more
europepmc   +1 more source

Aged murine bone marrow myeloid and mesenchymal cells develop unique senescence phenotypes. [PDF]

open access: yesJ Clin Invest
Doolittle ML   +7 more
europepmc   +1 more source

Deletion of the p16 and p15 Genes in Human Bladder Tumors

open access: yesJNCI Journal of the National Cancer Institute, 1995
Two genes, p16 (also known as CDKN2, INK4A, or MTS1) and p15 (also described as INK4B or MTS2), are found in tandem at chromosome 9p21. These genes are designated as candidate tumor suppressor genes because they encode proteins that function as negative cell cycle regulators. (The encoded polypeptides inactivate specific cyclin-protein kinase complexes
I, Orlow   +9 more
openaire   +3 more sources

Study on P16 gene in acute leukemia

Current Medical Science, 2000
To study the change of suppressing cancer gene P16 in acute leukemia, the P16 antigen expression of leukemia cell surfaces in 61 cases were investigated with ABC assay and gene structural defects in 51 cases of acute leukemia were examined with multiple comparative PCR method.
Y, Chen, H, Zhang, B, Yue, H, Li
openaire   +2 more sources

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