Results 231 to 240 of about 255,591 (268)

P53 Gene Mutations in Pituitary Carcinomas

Endocrine Pathology, 2007
Although p53 overexpression detected by immunohistochemistry has been reported in pituitary adenomas and carcinomas, genetic mutations in the p53 gene have not been previously detected in these tumors. We analyzed a series of eight pituitary adenomas and six pituitary carcinomas by immunohistochemistry, polymerase chain reaction amplification, and ...
Yoshinori, Tanizaki, Long, Jin, Bernd W, Scheithauer, Kalman, Kovacs, Federico, Roncaroli, Ricard V, Lloyd   +5 more
openaire   +2 more sources

p53 gene mutation in thyroid carcinoma

Cancer Letters, 1996
The pattern of p53 protein expression was examined in 92 cases of thyroid carcinoma. When the cases were divided into two groups with regard to their cytoplasmic staining only or nucleus staining only, the frequency of the nucleus staining group was significantly higher in the poorly differentiated carcinoma (PDC) and undifferentiated carcinoma (UDC ...
Y S, Ho, S C, Tseng, T Y, Chin, L L, Hsieh, J D, Lin   +4 more
openaire   +2 more sources

The p53 Gene and Cancer

2019
This tutorial describes the structure and function of the p53 protein, how its activity is regulated in cells, and how mutant versions of p53 can lead to cancer.
openaire   +1 more source

Expression of the p53 and nm23 Genes in Cholesteatoma

Acta Oto-Laryngologica, 2002
To evaluate the roles of p53 and nm23 genes in cholesteatoma.The results of p53 and nm23 immunostainings were compared between 28 cholesteatoma samples and 13 control skin samples obtained from the external acoustic canal.There were no correlations between p53 staining and either gender or type of cholesteatoma (p < 0.05).
Yildirim A, Bayazit, Kemal, Bakir, Muzaffer, Kanlikama, Enver, Ozer, Semih, Mumbuc, Ilyas, Disikirik, Ramazan, Ucak   +6 more
openaire   +2 more sources

Mutagenesis in the P53 gene

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1997
G P, Pfeifer, G P, Holmquist
openaire   +2 more sources

p53 Gene Therapy

American Journal of Cancer, 2002
N. Saadatmandi, D.R. Wilson, R.A. Gjerset   +2 more
openaire   +2 more sources

Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site

Cancer Cell, 2021
Shuo Chen, Li-Li Wu, Ni Yan
exaly  

p53 and p53 ‐regulated genes in bladder cancer

British Journal of Urology, 1998
P E, Keegan, J, Lunec, D E, Neal
openaire   +2 more sources

p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)

Cell, 2021
Maya Maor-Nof, Zohar Shipony, Rodrigo López-González   +2 more
exaly  

Mutant p53 suppresses innate immune signaling to promote tumorigenesis

Cancer Cell, 2021
Monisankar Ghosh, Alejandro Parrales, Tomoo Iwakuma   +2 more
exaly