Results 21 to 30 of about 818,447 (288)
Epigenetic control of Epstein–Barr virus transcription – relevance to viral life cycle? [PDF]
, 2013 DNA methylation normally leads to silencing of gene expression but Epstein–Barr virus (EBV) provides an exception to the epigenetic paradigm. DNA methylation is absolutely required for the expression of many viral genes.
Sinclair, Alison J
core +2 more sources
BMC Genomics, 2011 Background Kaposi's sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) are related human tumor viruses that cause primary effusion lymphomas (PEL) and Burkitt's lymphomas (BL), respectively.
Dresang Lindsay R +11 more
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Divergent Traits and Ligand-Binding Properties of the Cytomegalovirus CD48 Gene Family
Viruses, 2020 The genesis of gene families by the capture of host genes and their subsequent duplication is a crucial process in the evolution of large DNA viruses. CD48 is a cell surface molecule that interacts via its N-terminal immunoglobulin (Ig) domain with the ...
Pablo Martínez-Vicente +3 more
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Complexities associated with expression of Epstein-Barr virus (EBV) lytic origins of DNA replication. [PDF]
, 2007 EBV has two lytic origins (oriLyt) of DNA replication lying at divergent sites on the viral genome within a duplicated sequence (DS). The latter contains potential hairpin loops, ‘hinge’ elements and the promoters for transcripts from viral genes BHLF1 ...
Griffin, BE, Xue, SA
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Diversity and potential function of pig gut DNA viruses
Heliyon, 2023 Viruses are ubiquitous in the gut of animals and play an important role in the ecology of the gut microbiome. The potential effects of these substances on the growth and development of the body are not fully known.
Junjun Qin +8 more
doaj
Frontiers in Immunology, 2019 The activation of innate immunity by viral nucleic acids present in the cytoplasm plays an essential role in controlling viral infection in both immune and non-immune cells.
Xin Xie +3 more
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The interferon-stimulated gene IFITM3 restricts West Nile virus infection and pathogenesis [PDF]
, 2016 The interferon-induced transmembrane protein (IFITM) family of proteins inhibit infection of several different enveloped viruses in cell culture by virtue of their ability to restrict entry and fusion from late endosomes.
Bradbury LE +6 more
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Viral Vectors in Gene Therapy [PDF]
Diseases, 2018 Applications of viral vectors have found an encouraging new beginning in gene therapy in recent years. Significant improvements in vector engineering, delivery, and safety have placed viral vector-based therapy at the forefront of modern medicine. Viral vectors have been employed for the treatment of various diseases such as metabolic, cardiovascular ...
openaire +4 more sources
Localization of Frog Virus 3 Conserved Viral Proteins 88R, 91R, and 94L
Viruses, 2019 The characterization of the function of conserved viral genes is central to developing a greater understanding of important aspects of viral replication or pathogenesis.
Emily Penny, Craig R. Brunetti
doaj +1 more source
Genome editing technologies to fight infectious diseases [PDF]
, 2017 Genome editing by programmable nucleases represents a promising tool that could be exploited to develop new therapeutic strategies to fight infectious diseases.
Barzon, Luisa +2 more
core +1 more source