Results 51 to 60 of about 798,219 (310)

Persistent expression of Cotesia plutellae bracovirus genes in parasitized host, Plutella xylostella.

open access: yesPLoS ONE, 2018
Cotesia plutellae (= vestalis) bracovirus (CpBV) is symbiotic to an endoparasitoid wasp, C. plutellae, and plays crucial roles in parasitism against the diamondback moth, Plutella xylostella.
Yonggyun Kim, Sunil Kumar
doaj   +1 more source

Network analysis of Down syndrome and SARS-CoV-2 identifies risk and protective factors for COVID-19

open access: yesScientific Reports, 2021
SARS-CoV-2 infection has spread uncontrollably worldwide while it remains unknown how vulnerable populations, such as Down syndrome (DS) individuals are affected by the COVID-19 pandemic.
Ilario De Toma, Mara Dierssen
doaj   +1 more source

DPCIPI: A pre-trained deep learning model for predicting cross-immunity between drifted strains of Influenza A/H3N2 [PDF]

open access: yesarXiv, 2023
Predicting cross-immunity between viral strains is vital for public health surveillance and vaccine development. Traditional neural network methods, such as BiLSTM, could be ineffective due to the lack of lab data for model training and the overshadowing of crucial features within sequence concatenation.
arxiv  

Influenza A Virus Superinfection Potential Is Regulated by Viral Genomic Heterogeneity

open access: yesmBio, 2018
Defining the specific factors that govern the evolution and transmission of influenza A virus (IAV) populations is of critical importance for designing more-effective prediction and control strategies. Superinfection, the sequential infection of a single
Jiayi Sun, Christopher B. Brooke
doaj   +1 more source

Identification of Viral Taxon-Specific Genes (VTSG): Application to [PDF]

open access: yesGenomics & Informatics, 2018
Virus taxonomy was initially determined by clinical experiments based on phenotype. However, with the development of sequence analysis methods, genotype-based classification was also applied.
Shinduck Kang, Young-Chang Kim
doaj   +1 more source

RNA Sequencing of Medusavirus Suggests Remodeling of the Host Nuclear Environment at an Early Infection Stage

open access: yesMicrobiology Spectrum, 2021
Viruses of the phylum Nucleocytoviricota, or nucleo-cytoplasmic large DNA viruses (NCLDVs), undergo a cytoplasmic or nucleo-cytoplasmic cycle, the latter of which involves both nuclear and cytoplasmic compartments to proceed viral replication ...
Ruixuan Zhang   +3 more
doaj   +1 more source

Computational analysis of microRNA-mediated interactions in SARS-CoV-2 infection [PDF]

open access: yesPeerJ, 2020
MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression found in more than 200 diverse organisms. Although it is still not fully established if RNA viruses could generate miRNAs, there are examples of miRNA like sequences from RNA ...
Müşerref Duygu Saçar Demirci   +1 more
doaj   +2 more sources

Gene transfer by viral vectors for gene therapy [PDF]

open access: yesJournal of Molecular Medicine, 1995
The search for useful virus vectors and for improvements in currently available retrovectors which may have the capability of transportation by natural transport systems in the human body will open effective ways for targeting human genes to specific cells in tissues in situ.
Gholamreza Darai, Yechiel Becker
openaire   +3 more sources

Non-Viral Gene Delivery Systems [PDF]

open access: yesPharmaceutics, 2021
The advances in the field of gene therapy have significantly improved the possibility for nucleic acids as highly promising agents for the treatment of both inherited and acquired human diseases [...]
openaire   +4 more sources

The dual nature of TDC – bridging dendritic and T cells in immunity

open access: yesFEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Home - About - Disclaimer - Privacy