Results 51 to 60 of about 818,447 (288)
Characteristics of Wetting-Induced Bacteriophage Blooms in Biological Soil Crust. [PDF]
, 2019 Biological soil crusts (biocrusts) are photosynthetic "hot spots" in deserts and cover ∼12% of the Earth's terrestrial surface, and yet they face an uncertain future given expected shifts in rainfall events.
Northen, Trent R +4 more
core +2 more sources
Gene transfer by viral vectors for gene therapy [PDF]
Journal of Molecular Medicine, 1995 The search for useful virus vectors and for improvements in currently available retrovectors which may have the capability of transportation by natural transport systems in the human body will open effective ways for targeting human genes to specific cells in tissues in situ.
Gholamreza Darai, Yechiel Becker
openaire +3 more sources
Non-Viral Gene Delivery Systems [PDF]
Pharmaceutics, 2021 The advances in the field of gene therapy have significantly improved the possibility for nucleic acids as highly promising agents for the treatment of both inherited and acquired human diseases [...]
openaire +5 more sources
FEBS Letters, EarlyView.Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke +2 more
wiley +1 more source
Influenza A Virus Superinfection Potential Is Regulated by Viral Genomic Heterogeneity
mBio, 2018 Defining the specific factors that govern the evolution and transmission of influenza A virus (IAV) populations is of critical importance for designing more-effective prediction and control strategies. Superinfection, the sequential infection of a single
Jiayi Sun, Christopher B. Brooke
doaj +1 more source
Computational analysis of microRNA-mediated interactions in SARS-CoV-2 infection [PDF]
PeerJ, 2020 MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression found in more than 200 diverse organisms. Although it is still not fully established if RNA viruses could generate miRNAs, there are examples of miRNA like sequences from RNA ...
Müşerref Duygu Saçar Demirci +1 more
doaj +2 more sources
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Identification of Viral Taxon-Specific Genes (VTSG): Application to [PDF]
Genomics & Informatics, 2018 Virus taxonomy was initially determined by clinical experiments based on phenotype. However, with the development of sequence analysis methods, genotype-based classification was also applied.
Shinduck Kang, Young-Chang Kim
doaj +1 more source
Complementary transcriptomic, lipidomic, and targeted functional genetic analyses in cultured Drosophila cells highlight the role of glycerophospholipid metabolism in Flock House virus RNA replication [PDF]
, 2010 Background Cellular membranes are crucial host components utilized by positive-strand RNA viruses for replication of their genomes. Published studies have suggested that the synthesis and distribution of membrane lipids are particularly important for the
Castorena, Kathryn M +2 more
core +4 more sources
Resisting viral infection: the gene by gene approach [PDF]
Current Opinion in Virology, 2011 This review focuses on genes required for resistance to mouse cytomegalovirus (MCMV), as identified through unbiased genetic screening. Components of the developmental, sensing, and effector pathways, functioning in multiple cell types, were detected by infecting 22,000 G3 mutant mice with MCMV at an inoculum easily contained by WT animals.
Bruce Beutler, Eva Marie Y Moresco
openaire +2 more sources