Results 51 to 60 of about 17,032 (179)

Elevated ZNF704 expression is associated with poor prognosis of uveal melanoma and promotes cancer cell growth by regulating AKT/mTOR signaling

, 2023
Background Uveal melanoma (UM) is the most common intraocular malignancy in adults, with a poor survival prognosis. To date, limited understanding of UM’s molecular mechanisms constitutes an obstacle to developing effective therapy.
Xiu, Jingying, Feng, Zhaoxun, Wei, Wenbin, Luo, Jingting, Li, Haowen, Zhao, Hanqing, Li, Yang, Zeng, Jingyao   +7 more
core   +1 more source

Molecular diagnosis of a laboratory mouse papillomavirus (MusPV).

, 2012
MusPV, a novel papillomavirus (PV) that naturally infects laboratory mice, was isolated and characterized from a colony of NMRI-Foxn1(nu)/Foxn1(nu) (nude) mice in India.
Silva, Kathleen A, Ghim, Shin-Je, Potter, Christopher S, Proctor, Mary, Sundberg, John P, Joh, Joongho, Ingle, Arvind, Jenson, A Bennett   +7 more
core   +1 more source

Cancer-initiating cells derived from established cervical cell lines exhibit stem-cell markers and increased radioresistance [PDF]

, 2012
Background Cancer-initiating cells (CICs) are proposed to be responsible for the generation of metastasis and resistance to therapy. Accumulating evidences indicates CICs are found among different human cancers and cell lines derived from them.
Pérez-Plasencia Carlos, Veverly Mendoza-Martínez, García-Carrancá Alejandro, Carlos Pérez-Plasencia, Jacqueline López, López Jacqueline, Adela Poitevin, Alejandro García-Carrancá, Poitevin Adela, Mendoza-Martínez Veverly   +9 more
core   +1 more source

PAK3 is a key signature gene of the glioma proneural subtype and affects its proliferation, differentiation and growth

, 2021
International audiencePurpose Gliomas are the most lethal adult primary brain cancers. Recent advances in their molecular characterization have contributed to a better understanding of their pathophysiology, but there is still a need to identify key ...
Rousseau, Véronique, Gleize, Vincent, Magne, Nathalie, Sanson, Marc, Idbaih, Ahmed, Schmitt, Charlotte, Castel, Hélène, Duarte, Kévin, Barnier, Jean-Vianney, Mutel, Alexandre, Poëa-Guyon, Sandrine, Huillard, Emmanuelle   +11 more
core   +1 more source

Inhibition of Sonic Hedgehog signaling reduces tumor growth in pancreatic cancer in vitro and in vivo

, 2008
Die Aktivierung des Hedgehog-Patched-Signaltransduktionsweges, welcher durch die Bindung von Hegdehog-Proteinen an den Transmembranrezeptor PTCH oder durch Mutationen im PTCH-Gen selbst aktiviert wird, spielt eine wesentliche Rolle in der Entstehung ...
Bahra, Marcus
core   +1 more source

Scrotal squamous cell carcinoma: Two HPV‐negative cases with probable UV‐ induced pathogenesis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Daniel Craus, Ulrike Wieland, Steffi Silling, Julia Hyun, Milan Vidakovic, Frank Oellig, Alexander Kreuter, Valentina Laura Müller   +7 more
wiley   +1 more source

Effect of MUC16 in 3T3 cells.

, 2015
A) Soft agar growth of 3T3 transfectants in 60 mm dishes. After 14 days, colonies were counted and plotted. The data shown in the table represent one of three similar experiments (*** p < 0.0001) compared to the phrGFP control vector; B) Matrigel ...
Huasong Tian (286490), David Solit (737882), Sahityasri Thapi (737878), Sebastien Monette (737880), Xun Ma (737876), Xiujun Yan (737877), David R. Spriggs (737883), Nikolaus Schultz (169137), David M. Hyman (737881), Douglas A. Levine (175510), Amy Wang (159932), Thapi D. Rao (737875), Nestor Rosales (737879)   +12 more
core   +1 more source

Identification of PADI2 as a potential breast cancer biomarker and therapeutic target

, 2012
Background We have recently reported that the expression of peptidylarginine deiminase 2 (PADI2) is regulated by EGF in mammary cancer cells and appears to play a role in the proliferation of normal mammary epithelium; however, the role of PADI2 in the ...
Gray Joe W, Coonrod Scott A, Palmer Ashley M, Causey Corey P, McElwee John L, Howe Louise R, Subramanian Venkataraman, Mohanan Sunish, Thompson Paul R, Breuer Heike C, Anguish Lynne J, Cherrington Brian D, Griffith Obi L   +12 more
core   +1 more source

Successful xenografting of cryopreserved primary pancreatic cancers.

, 2001
n order to assess the suitability of cryopreserved neoplastic tissues for xenografting into nude (nu/nu) mice, we compared the take rate in 28 samples of pancreatic ductal carcinoma.
CRISTOFORI P, SORIO C, ORLANDINI S, BONORA, Adriana, GAVIRAGHI G, PEDERZOLI, Paolo, MARCHIORI P, ZAMBONI, Giuseppe, DAL NEGRO G, BONORA A, ZAMBONI G, FALCONI, Massimo, ORLANDINI, Simonetta, SCARPA, Aldo, Capelli, Paola, MOORE PS, P. PEDERZOLI, SCARPA A., CAPELLI P, SORIO, Claudio   +19 more
core  

Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

, 2015
At the time of publication, Paul Thompson was not yet affiliated with UMass Medical School.BACKGROUND: We have recently reported that the expression of peptidylarginine deiminase 2 (PADI2) is regulated by EGF in mammary cancer cells and appears to play a
Griffith, Obi L., Palmer, Ashley M., Subramanian, Venkataraman, Coonrod, Scott A., Breuer, Heike C., McElwee, John L., Anguish, Lynne J., Mohanan, Sunish, Thompson, Paul R, Gray, Joe W., Cherrington, Brian D., Howe, Louise R., Causey, Corey P.   +12 more
core   +1 more source