Results 41 to 50 of about 17,032 (179)

Anticancer effects of clinically acceptable colchicine concentrations on human gastric cancer cell lines

, 2016
Colchicine is a very cheap microtubule destabilizer. Because microtubules are an ideal target for anticancer drugs, the purpose of this study was to investigate whether clinically acceptable colchicine concentrations have anticancer effects on gastric ...
Deng-Chyang Wu, Lin, Zu-Yau, Kuo, Chao-Hung, Zu-Yau Lin, Wu, Deng-Chyang, Chuang, Wan-Long, Chao-Hung Kuo, Wan-Long Chuang   +7 more
core   +1 more source

The effect of photodynamic therapy in head and neck cancer: A comprehensive review of in vivo models

Photochemistry and Photobiology, EarlyView.
This review evaluates Photodynamic Therapy (PDT) in in vivo head and neck cancer models. PDT effectively generates ROS, reducing tumor growth, cell proliferation and angiogenesis while enhancing survival and immune responses. However, methodological heterogeneity highlights the urgent need for standardized dosimetric protocols to ensure reproducibility
Bibiana Padilha de Menezes da Silva, Rebeca Barros Nascimento, Giovanna Lopes Carvalho, Rebeca Boltes Cecatto, Maria Stella Moreira, Maria Fernanda Setúbal Destro Rodrigues   +5 more
wiley   +1 more source

Understanding exosomes in facial esthetics and skin aging

Periodontology 2000, EarlyView.
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron, Catherine Davies, Anton Sculean, Paras Ahmad   +3 more
wiley   +1 more source

Contrast Agents for Enhanced Bioimaging: A Comprehensive Review

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Contrast agents, especially those that are nanoparticle‐based, are revolutionizing bioimaging by enabling highly sensitive, specific, and early‐stage diagnosis of diseases like cancer, using clinical imaging modalities such as CT, MRI, PET, and SPECT.
Paulo Sérgio Taube, Donald Fernandes, Arthur Abinader Vasconcelos, Hugo de Campos Braga, Alan Kelbis Oliveira Lima, José Arnaldo Santana Costa, Karla Furtado Andriani, Ester da Cunha Meira Santos, Antonio Jorge Silva Araújo Junior, Hauster Maximiler Campos de Paula, Wallace Júnio Reis, Kashif Gul, Nida Wahab, Luis Carlos Resio, Elisa Kawana Leal dos Santos, Márcio Peres de Araujo, Matheus Allen P. da Silva, Juliana Paula da Silva   +17 more
wiley   +1 more source

ALTERAZIONI ISTOPATOLOGICHE INDOTTE DA CELLULE UMANE LAM/TSC IN TOPI NUDI: UN MODELLO DI LINFANGIOLEIOMIOMATOSI. REVERSIONE DEL DANNO CON ANTICORPO ANTI-EGFR [PDF]

, 2012
LAM is a rare and progressive disease characterized by widespread proliferation of abnormal smooth muscle-like cells (LAM cells). LAM cells cause cystic destruction of lung parenchyma, abdominal tumours (angiomyolipoma, AML) and infiltration of axial ...
E. Chiaramonte
core   +1 more source

HIV Infection and Opioid Treatment Enable the Engraftment of Kaposi Sarcoma‐Like Tumors Into Immunocompetent Mice

Journal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT The Kaposi Sarcoma herpesvirus (KSHV) causes Kaposi sarcoma (KS), primary effusion lymphoma, a lymphoproliferative disease (KSHV‐multicentric Castleman's disease), and a cytokine inflammatory syndrome (KICS). These diseases occur more frequently, though not exclusively, among people living with HIV or other types of immune dysregulation. While
Julian Naipauer, Ezequiel Lacunza, Anuj Ahuja, Santas Rosario, Carolina Alejandra Alvarez Canete, Martin C. Abba, Ethel Cesarman, Sundaram Ramakrishnan, Enrique Mesri, Sabita Roy, Umakant Sharma   +10 more
wiley   +1 more source

A mouse LAM model by endonasal administration of human TSC2 deficient smooth muscle cells

, 2010
RATIONALE: Lymphangioleiomyomatosis (LAM) is a progressive and interstitial lung disease characterized by diffuse proliferation and invasion of abnormal smooth muscle cells in involved organs, cystic degeneration of lung parenchyma, infiltration of the ...
Anna Maria Di Giulio, Alfredo Gorio, S. Ancona, Silvia Ancona, Elena A. Lesma, E. Chiaramonte, V. Grande, Vera Grande, Eloisa Chiaramonte, E. Lesma, A.M. Di Giulio, A. Gorio   +11 more
core   +1 more source

ADAM8 beeinflusst das Fortschreiten von Glioblastomen über Mikroglia/Makrophagen, indem es die osteopontin-vermittelte Angiogenese reguliert

, 2023
This cumulative dissertation summarizes two peer-reviewed publications addressing the role of a Disintegrin and Metalloproteases 8 (ADAM8) in Glioblastoma multiforme (GBM) cells and in the GBM tumor microenvironment.
Li , Yu
core   +1 more source

Comparative Ionomics of Lycopodiaceae and Selaginellaceae Across Diverse Soil Types in Japan

Ecological Research, Volume 41, Issue 4, July 2026.
We conducted a comparative ionomic analysis of Lycopodiaceae and Selaginellaceae collected from diverse soil types in Japan, including serpentine soils and solfatara fields, to examine how evolutionary lineage and soil environment shape elemental composition in lycophytes.
Akinori Ren, Asuka Saisako, Takato Saito, Akihiro Yamamoto, Soshi Osaki, Akari Matsumoto, Daisuke Aoshima, Hirotsuna Yamada, Takayuki Nakatsubo, Toshihiro Watanabe, Hayato Maruyama, Takuro Shinano, Jun Wasaki   +12 more
wiley   +1 more source

Effects of human arylamine N-acetyltransferase I knockdown in triple-negative breast cancer cell lines

, 2015
Expression of human arylamine N-acetyltransferase I (NAT1) has been associated with various cancer subtypes and inhibition of this enzyme with small molecule inhibitors or siRNA affects cell growth and survival.
Tiang, Jacky M., Rodney F. Minchin, Jacky M. Tiang, Minchin, Rodney F., Neville J. Butcher, Butcher, Neville J.   +5 more
core   +1 more source