Amerindian (but not African or European) ancestry is significantly associated with diurnal preference within an admixed Brazilian population [PDF]
, 2017 Significant questions remain unanswered regarding the genetic versus environmental contributions to racial/ethnic differences in sleep and circadian rhythms.
Beijamini, Felipe +12 more
core +1 more source
To what extent does genealogical ancestry imply genetic ancestry? [PDF]
Theoretical Population Biology, 2008 Recent statistical and computational analyses have shown that a genealogical most recent common ancestor (MRCA) may have lived in the recent past. However, coalescent-based approaches show that genetic most recent common ancestors for a given non-recombining locus are typically much more ancient.
Matsen, Frederick A., Evans, Steven N.
openaire +4 more sources
Association of serum lipid components and obesity with genetic ancestry in an admixed population of elderly women [PDF]
, 2012 The prevalence of metabolic disorders varies among ethnic populations and these disorders represent a critical health care issue for elderly women. This study investigated the correlation between genetic ancestry and body composition, metabolic traits ...
Lins, Tulio Cesar de Lima +7 more
core +3 more sources
Genetic ancestry and radical prostatectomy findings in Hispanic/Latino patients
Frontiers in OncologyBackgroundAfrican ancestry is a known factor associated with the presentation and aggressiveness of prostate cancer (PC). Hispanic/Latino populations exhibit varying degrees of genetic admixture across Latin American countries, leading to diverse levels ...
Natalia L. Acosta-Vega +12 more
doaj +1 more source
Contribution of common and rare variants to bipolar disorder susceptibility in extended pedigrees from population isolates. [PDF]
, 2020 Current evidence from case/control studies indicates that genetic risk for psychiatric disorders derives primarily from numerous common variants, each with a small phenotypic impact. The literature describing apparent segregation of bipolar disorder (BP)
Aldana, Ileana +37 more
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Genetic Ancestry and Health [PDF]
MOJ Immunology, 2017 Information about genetic ancestry has a great value in health studies and other related areas of expertise such as anthropology, forensics and pharmacogenomics. In this review, we highlight several aspects of health that can be significantly improved by better understanding of genetic ancestry.
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Improving polygenic prediction with genetically inferred ancestry
Human Genetics and Genomics Advances, 2022 Genome-wide association studies (GWASs) have demonstrated that most common diseases have a strong genetic component from many genetic variants each with a small effect size. GWAS summary statistics have allowed the construction of polygenic scores (PGSs) estimating part of the individual risk for common diseases.
Naret, O. +5 more
openaire +4 more sources
The effects of socioeconomic status, clinical factors, and genetic ancestry on pulmonary tuberculosis disease in northeastern Mexico. [PDF]
PLoS ONE, 2014 Diverse socioeconomic and clinical factors influence susceptibility to tuberculosis (TB) disease in Mexico. The role of genetic factors, particularly those that differ between the parental groups that admixed in Mexico, is unclear. The objectives of this
Bonnie N Young +8 more
doaj +1 more source
Detecting individual ancestry in the human genome [PDF]
, 2015 Detecting and quantifying the population substructure present in a sample of individuals are of main interest in the fields of genetic epidemiology, population genetics, and forensics among others.
Lao Grueso, O. (Oscar) +1 more
core +4 more sources
Association of genetic ancestry with colorectal tumor location in Puerto Rican Latinos
Human Genomics, 2019 Background Colorectal cancer (CRC) is the first cause of cancer deaths among Puerto Ricans. The incidence and mortality of CRC in Puerto Rico continue to be on the rise.
Julyann Pérez-Mayoral +13 more
doaj +1 more source