Results 31 to 40 of about 232,752 (292)

What’s at stake? Determining indigeneity in the era of DIY DNA

open access: yesNew Genetics and Society, 2019
Social scientists have found that direct-to-consumer genetic ancestry testing can increase the influence of genetic notions of identity, but has a varying effect on test takers depending on the individual, social and political context.
Elizabeth Watt, Emma Kowal
doaj   +1 more source

Softwares and methods for estimating genetic ancestry in human populations

open access: yesHuman Genomics, 2013
The estimation of genetic ancestry in human populations has important applications in medical genetic studies. Genetic ancestry is used to control for population stratification in genetic association studies, and is used to understand the genetic basis ...
Liu Yushi   +5 more
doaj   +1 more source

Gut microbiota composition explains more variance in the host cardiometabolic risk than genetic ancestry

open access: yesGut Microbes, 2020
Cardiometabolic affections greatly contribute to the global burden of disease. The susceptibility to obesity, cardiovascular disease, and type-2 diabetes, conditions that add to the cardiometabolic syndrome (CMS), was associated with the ancestral ...
Sandra J. Guzmán-Castañeda   +6 more
doaj   +1 more source

Molecular Genetic Influences on Normative and Problematic Alcohol Use in a Population-Based Sample of College Students [PDF]

open access: yes, 2017
Background: Genetic factors impact alcohol use behaviors and these factors may become increasingly evident during emerging adulthood. Examination of the effects of individual variants as well as aggregate genetic variation can clarify mechanisms ...
Adkins, Amy   +16 more
core   +2 more sources

Phenotypic variance explained by local ancestry in admixed African Americans

open access: yesFrontiers in Genetics, 2015
We surveyed 26 quantitative traits and disease outcomes to understand the proportion of phenotypic variance explained by local ancestry in admixed African Americans. After inferring local ancestry as the number of African-ancestry chromosomes at hundreds
Daniel eShriner   +6 more
doaj   +1 more source

The relationship between donor-recipient genetic distance and long-term kidney transplant outcome [version 1; peer review: 2 approved]

open access: yesHRB Open Research, 2020
Background: We set out to quantify shared genetic ancestry between unrelated kidney donor-recipient pairs and test it as a predictor of time to graft failure.
Caragh P. Stapleton   +4 more
doaj   +1 more source

Enhanced methods for local ancestry assignment in sequenced admixed individuals. [PDF]

open access: yes, 2014
Inferring the ancestry at each locus in the genome of recently admixed individuals (e.g., Latino Americans) plays a major role in medical and population genetic inferences, ranging from finding disease-risk loci, to inferring recombination rates, to ...
Brown, Robert, Pasaniuc, Bogdan
core   +2 more sources

Amerindian genetic ancestry as a risk factor for tuberculosis in an amazonian population.

open access: yesPLoS ONE, 2020
In recent years, the incidence of tuberculosis (TB) has declined worldwide, although this disease still occurs at relatively high rates in Amerindian populations.
Diana Feio da Veiga Borges Leal   +11 more
doaj   +1 more source

Genetic ancestry of patients with porphyria cutanea tarda in a country with mixed races: a cross-sectional study (Rio de Janeiro - Brazil) [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2018
: Porphyria cutanea tarda has a complex etiology with genetic factors not completely elucidated. The miscegenation of the Brazilian population has important implications in the predisposition to diseases.
Isabella Brasil Succi   +3 more
doaj   +1 more source

Genetic ancestry, differential gene expression, and survival in pediatric B‐cell acute lymphoblastic leukemia

open access: yesCancer Medicine, 2023
Background Black children have lower incidence yet worse survival than White and Latinx children with B‐cell acute lymphoblastic leukemia (B‐ALL). It is unclear how reported race/ethnicity (RRE) is associated with death in B‐ALL after accounting for ...
Freddy A. Barragan   +6 more
doaj   +1 more source

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