Results 11 to 20 of about 115,560 (262)

Genetic ancestry and ethnic identity in Ecuador

open access: yesHuman Genetics and Genomics Advances, 2021
We investigated the ancestral origins of four Ecuadorian ethnic groups-Afro-Ecuadorian, Mestizo, Montubio, and the Indigenous Tsáchila-in an effort to gain insight on the relationship between ancestry, culture, and the formation of ethnic identities in Latin America.
Aroon T Chande   +2 more
exaly   +4 more sources

Defining Genetic Ancestry: Implications for Nurses. [PDF]

open access: yesBiol Res Nurs
Introduction: This paper provides an overview of methods for measuring genetic ancestry, specifically focusing on applications for nurses engaged in research. We describe methods and current tools widely implemented by the research community to introduce nurses who conduct research in the landscape of measuring ...
Jimenez A   +5 more
europepmc   +3 more sources

Genetic ancestry and population structure in the All of Us Research Program cohort [PDF]

open access: yesNature Communications
We analyzed participant genomic variant data to characterize population structure and genetic ancestry for the All of Us cohort (n = 297,549). There is substantial population structure in the cohort, with clusters of closely related participants ...
Shivam Sharma   +7 more
doaj   +2 more sources

Power and Limitations of Inferring Genetic Ancestry. [PDF]

open access: yesAnn Hum Genet
ABSTRACTBackgroundThe recent emergence of technologies that capture and analyse genetic variation patterns obtained from a person's DNA sample has led to numerous academic and commercial endeavours to infer individuals' ancestries. In theory, a person's genome contains a wealth of readily accessible information regarding their ancestors, despite only ...
Bird N, King T, Hellenthal G.
europepmc   +4 more sources

A geographic history of human genetic ancestry. [PDF]

open access: yesScience
Describing the distribution of genetic variation across individuals is a fundamental goal of population genetics. In humans, traditional approaches for describing population genetic variation often rely on discrete genetic ancestry labels, which, despite their utility, can obscure the complex, multifaceted nature of human genetic history.
Grundler MC, Terhorst J, Bradburd GS.
europepmc   +4 more sources

A Comparative Analysis of Genetic Ancestry and Admixture in the Colombian Populations of Chocó and Medellín

open access: yesG3: Genes, Genomes, Genetics, 2017
At least 20% of Colombians identify as having African ancestry, yielding the second largest population of Afro-descendants in Latin America. To date, there have been relatively few studies focused on the genetic ancestry of Afro-Latino populations.
Andrew B. Conley   +6 more
doaj   +3 more sources

Incorporating local ancestry improves identification of ancestry-associated methylation signatures and meQTLs in African Americans

open access: yesCommunications Biology, 2022
Here we report three epigenome-wide association studies (EWAS) of DNA methylation on self-reported race, global genetic ancestry, and local genetic ancestry in admixed Americans from three sets of samples, including internal and external replications (N ...
Boyang Li   +6 more
doaj   +1 more source

Ancestry: How researchers use it and what they mean by it

open access: yesFrontiers in Genetics, 2023
Background: Ancestry is often viewed as a more objective and less objectionable population descriptor than race or ethnicity. Perhaps reflecting this, usage of the term “ancestry” is rapidly growing in genetics research, with ancestry groups referenced ...
Bege Dauda   +15 more
doaj   +1 more source

A method for an unbiased estimate of cross-ancestry genetic correlation using individual-level data

open access: yesNature Communications, 2023
Cross-ancestry genetic correlation can reveal differences in the genetic basis of traits between populations, but methods can be biased by ancestry-specific genetic architecture. Here, the authors present a method to for estimating cross-ancestry genetic
Md. Moksedul Momin   +5 more
doaj   +1 more source

Race, Ethnicity and Ancestry in Unrelated Transplant Matching for the National Marrow Donor Program: A Comparison of Multiple Forms of Self-Identification with Genetics. [PDF]

open access: yesPLoS ONE, 2015
We conducted a nationwide study comparing self-identification to genetic ancestry classifications in a large cohort (n = 1752) from the National Marrow Donor Program.
Jill A Hollenbach   +6 more
doaj   +1 more source

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