Results 21 to 30 of about 115,560 (262)

Genomic supremacy: the harm of conflating genetic ancestry and race

open access: yesHuman Genomics, 2022
Background Recent studies have reignited the tinderbox of debate surrounding the use of race and ancestry in medicine. These controversial studies have argued for a strong correlation between genetic ancestry and race, justifying continued use of genetic
Jessica P. Cerdeña   +2 more
doaj   +1 more source

Mapping Human Genetic Ancestry [PDF]

open access: yesMolecular Biology and Evolution, 2007
The human genome is a mosaic with respect to its evolutionary history. Based on a phylogenetic analysis of 23,210 DNA sequence alignments from human, chimpanzee, gorilla, orangutan, and rhesus, we present a map of human genetic ancestry. For about 23% of our genome, we share no immediate genetic ancestry with our closest living relative, the chimpanzee.
Ingo, Ebersberger   +5 more
openaire   +2 more sources

Identity and genetic ancestry tracing [PDF]

open access: yesBMJ, 2002
Tracing genetic identity can lead to resolution of uncertainty but can cause more problems than it solves. Will establishment of genetic identity be cohesive or divisive? What can our genes tell us about who we are? The answer to that question depends on exactly what you want to know.
Carl, Elliott, Paul, Brodwin
openaire   +2 more sources

Guidelines for genetic ancestry inference created through roundtable discussions

open access: yesHGG Advances, 2023
Summary: The use of genetic and genomic technology to infer ancestry is commonplace in a variety of contexts, particularly in biomedical research and for direct-to-consumer genetic testing.
Jennifer K. Wagner   +6 more
doaj   +1 more source

Co-constructing ancestry through direct-to-consumer genetic testing

open access: yesTATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2021
Direct-to-consumer (DTC) genetic ancestry tests offered via the internet supposedly uncover the ancestry of those tested. While these tests might be seen as a means to find a biologically inscribed and fixed genealogy, this paper explores how companies ...
Alexander Lang, Florian Winkler
doaj   +1 more source

Visualizing Genetic Programming Ancestries [PDF]

open access: yesProceedings of the 2016 on Genetic and Evolutionary Computation Conference Companion, 2016
Previous work has demonstrated the utility of graph databases as a tool for collecting, analyzing, and visualizing ancestry in evolutionary computation runs. That work focused on sections of individual runs, whereas this paper illustrates the application of these ideas on the entirety of large runs (up to three hundred thousand individuals) and ...
Nicholas Freitag McPhee   +4 more
openaire   +1 more source

Genetic Ancestry in Lung-Function Predictions [PDF]

open access: yesNew England Journal of Medicine, 2010
Self-identified race or ethnic group is used to determine normal reference standards in the prediction of pulmonary function. We conducted a study to determine whether the genetically determined percentage of African ancestry is associated with lung function and whether its use could improve predictions of lung function among persons who identified ...
Kumar R.   +27 more
openaire   +2 more sources

CoAIMs: a cost-effective panel of ancestry informative markers for determining continental origins. [PDF]

open access: yesPLoS ONE, 2010
Genetic ancestry is known to impact outcomes of genotype-phenotype studies that are designed to identify risk for common diseases in human populations.
Eric R Londin   +8 more
doaj   +1 more source

Gut microbiota composition explains more variance in the host cardiometabolic risk than genetic ancestry

open access: yesGut Microbes, 2020
Cardiometabolic affections greatly contribute to the global burden of disease. The susceptibility to obesity, cardiovascular disease, and type-2 diabetes, conditions that add to the cardiometabolic syndrome (CMS), was associated with the ancestral ...
Sandra J. Guzmán-Castañeda   +6 more
doaj   +1 more source

Ancestry inference using principal component analysis and spatial analysis: a distance-based analysis to account for population substructure

open access: yesBMC Genomics, 2017
Background Accurate inference of genetic ancestry is of fundamental interest to many biomedical, forensic, and anthropological research areas. Genetic ancestry memberships may relate to genetic disease risks.
Jinyoung Byun   +5 more
doaj   +1 more source

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