Results 81 to 90 of about 226,034 (265)

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Population stratification and genetic association studies in South Asia

, 2005
Population stratification and its influence on genetic association studies is a controversial topic. Although it has been suggested that stratification is unlikely to bias the results of association studies conducted in developed countries, convincing ...
Bittles, Alan, Bittles, A.H.
core  

Analysis of SIRT1 genetic variants in young Mexican individuals: relationships with overweight and obesity

Frontiers in Genetics
The high prevalence of obesity in Mexico starting from the early stages of life is concerning and represents a major public health problem. Genetic association studies have reported that single nucleotide variants (SNVs) in SIRT1, an NAD+-dependent ...
S. Salazar-García, A. Ibáñez-Salazar, E. Lares-Villaseñor, Noemi Gaytan Pacheco, E. Uresti-Rivera, D. P. Portales-Pérez, U. De la Cruz-Mosso, J. M. Vargas-Morales   +7 more
doaj   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits [PDF]

, 2011
Nonalcoholic fatty liver disease (NAFLD) clusters in families, but the only known common genetic variants influencing risk are near PNPLA3. We sought to identify additional genetic variants influencing NAFLD using genome-wide association (GWA) analysis ...
Palmer Cameron D., Schwartz, SM, Benjamin F Voight, Fox, Caroline S., Hwang, Shih-Jen, GIANT Consortium, Launer, Lenore, Hernaez, R, Melissa E. Garcia, Hwang, SJ, Pietiläinen, Kirsi Hannele, Harris, Tamara B, Mitchell, Braxton D., CRISPONI, LAURA, Butler, Johannah L, Massaro, J.M., Gudnason, V., Feitosa, MF, Jeanne M. Clark, Massaro, J., Jørgensen, Torben, O'Donnell Christopher J., Stephen M. Schwartz, Schwartz SM, Palmer, C., Eiriksdottir, Gudny, Joel N Hirschhorn, Kao W. H. Linda, Laura M. Yerges-Armstrong, Stephen M Schwartz, Jeanne M Clark, Borecki Ingrid B., Mitchell, Braxton, Smith, AV, null null, Palmer, C.D., Kao, W.H.L., Johannah L. Butler, Butler, Johannah L., Borecki, IB, Palmer CD, Salomaa, V., Hirschhorn, Joel, Borecki, Ingrid B., Johannah L Butler, Speliotes, Elizabeth K, Fox Caroline S., Shuldiner, Alan R., Fox CS, Hoffmann, Udo, Palmer, CD, Nalls, Michael, Garcia, Melissa E, Hwang SJ, Wu, Jun, Mary F Feitosa, Massaro, Joseph M., Eiriksdottir G, Schadt, EE, Voight, Benjamin F, Nalls, Michael A., Clark, Jeanne M., Eiriksdottir, G, Smith AV, O'Donnell, CJ, Sahani DV, NASH CRN, Schwartz Stephen M., Lauren J Kim, CJ, Butler Johannah L., Speliotes, Elizabeth K., Tamara B Harris, Speliotes, E.K., Feitosa, Mary F., Joseph M. Massaro, Caroline S. Fox, Smith, Albert V, Launer, Lenore J, Shuldiner Alan R., GOLD Consortium, Hoffmann, U, Harris, Tamara, Tamara B. Harris, Garcia Melissa E., Kao, W. H Linda, Albert V. Smith, Mitchell BD, Smith, A.V., Voight, BF, Voight, Benjamin F., Mary F. Feitosa, Alan R Shuldiner, Kim, L.J., Kao, W H Linda, Speliotes EK, Siscovick, DS, Schadt, Eric E., Fox, C.S., Vilmundur Gudnason, Sahani, Dushyant V, Ruben Hernaez, Raychaudhuri, Soumya, Cameron D Palmer, Dushyant V Sahani, Salomaa, Veikko, O'Donnell, Christopher J., Feitosa, Mary, Shuldiner AR, Carr, J Jeffrey, Harris, T.B., Speliotes Elizabeth K., Salomaa, V, Posthuma, D., Tomas, Marta, Palmer, Cameron D, Tomas, M, Wu Jun, Siscovick David S., Launer Lenore J., Palmer, Cameron, et al., de Geus, E.J.C.; id_orcid, Butler, J.L., Clark Jeanne M., Hernaez, R., Mitchell, Braxton D, Borecki, Ingrid B, Shuldiner, A.R., Voight Benjamin F., Benjamin F. Voight, Kao, WH Linda, Lenore J. Launer, Feitosa MF, Siscovick, David, Nalls, M.A., Carr, J. Jeffrey, Clark, JM, Garcia, Melissa E., Lenore J Launer, Hirschhorn Joel N., Hwang, S.J., Eiriksdottir, G., Launer, L.J., Laura M Yerges-Armstrong, Melissa E Garcia, Hwang, S., Christopher J O'Donnell, Yerges-Armstrong, Laura M., Clark, J., Kim Lauren J., Launer, Lenore J., Hirschhorn JN, Harris, Tamara B., Michael A. Nalls, Launer LJ, Boomsma, D.I.; id_orcid, J Jeffrey Carr, Massaro, JM, Braxton D. Mitchell, Posthuma, D.; id_orcid, Heijer, M. den, Shih-Jen Hwang, Siscovick, David S., Mitchell, BD, Siscovick DS, Gudnason V, Yerges-Armstrong, L.M., Launer, LJ (Lenore), Gudnason, Vilmundur, Veikko Salomaa, de Geus, E.J.C., O' DONNELL, Willemsen, G.; id_orcid, Mitchell, B., Shuldiner, Alan, Kim, Lauren J, Sahani Dushyant V., Smith Albert V., David S Siscovick, Schadt, Eric, Kao WH, Fox, CS, David S. Siscovick, Carr JJ, Butler, Johannah, Massaro, Joseph, Hoffmann U, Garcia, Melissa, Tomas Marta, Mitchell Braxton D., Christopher J. O'Donnell, Lokki, Marja-Liisa, Gudnason Vilmundur, Fox, Caroline, DIAGRAM Consortium, Schadt, E.E., Tomas M, Hirschhorn, J.N., Jun Wu, Nalls, M., Ingrid B Borecki, Launer, L., Harris TB, Palmer, Cameron D., O'Donnell, C.J., Nalls MA, Voight BF, Borecki IB, Salomaa V, Massaro, Joseph M, Voight, B.F., Nalls, MA, O'Donnell, Christopher J, Garcia, M., Harris Tamara B., Kao, W., Kao, WH, Elizabeth K Speliotes, Gudnason, V, Siscovick, D.S., Yerges-Armstrong, Laura, Siscovick, David S, Cameron D. Palmer, Smith, Albert, Garcia ME, Marta Tomas, Clark, Jeanne M, Eric E. Schadt, Hottenga, J.J., Wu, J, Caroline S Fox, Joel N. Hirschhorn, Wu, J., Hoffmann Udo, Schadt EE, Albert V Smith, Carr J. Jeffrey, Sahani, D.V., J. Jeffrey Carr, Michael A Nalls, Feitosa, Mary F, Kao, W.H., O'Donnell, Christopher, Kim LJ, Nalls Michael A., Feitosa Mary F., Schwartz, S.M., Smith, Albert V., Shuldiner, Alan R, Voight, Benjamin, Wu J, Alan R. Shuldiner, Borecki, Ingrid, Massaro Joseph M., Lauren J. Kim, Schwartz, Stephen M, SCUTERI, ANGELO, Kao, WHL, Speliotes, Elizabeth, Kim, LJ, Clark, Jeanne, Carr, J.J., Nalls, Michael A, Feitosa, M.F., Harris, TB, Willemsen, G., Hirschhorn, Joel N., Clark JM, Yerges-Armstrong, L., Ingrid B. Borecki, Eric E Schadt, Butler, J., Butler JL, Schwartz, Stephen, Yerges-Armstrong LM, Garcia, M.E., Hernaez Ruben, Shuldiner, AR, GIANT, Boomsma, D.I., Kim, L., Elizabeth K. Speliotes, O’Donnell, C., Clark, J.M., Yerges-Armstrong, Laura M, Kim, Lauren J., Garcia, ME, Joseph M Massaro, Mitchell, B.D., Massaro JM, Speliotes, EK, Kim, Lauren, Udo Hoffmann, Jansson, John-Olov,, W H Linda Kao, MAGIC Investigators, Launer, LJ, Shuldiner, A., Hirschhorn, Joel N, Salomaa Veikko, Dushyant V. Sahani, Hwang Shih-Jen, Tomas, M., Hernaez R, Geus, E.J.C. de, Borecki, I.B., Kao, W. H. Linda, Hwang, Shih Jen, Butler, JL, Sahani, Dushyant, Hirschhorn, JN, Sahani, Dushyant V., Speliotes, E., YERGES ARMSTRONG LM, Yerges-Armstrong Laura M., Hernaez, Ruben, Eiriksdottir Gudny, Sahani, DV, Gudny Eiriksdottir, Braxton D Mitchell, Schadt Eric E., Schadt, Eric E, Hoffmann, U., PAOLISSO, Giuseppe, Schwartz, Stephen M., W. H. Linda Kao, Carr, JJ, Yerges-Armstrong, LM, Fox, Caroline S   +329 more
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Causal association between obstructive sleep apnea and amyotrophic lateral sclerosis: a Mendelian randomization study

Frontiers in Aging Neuroscience
BackgroundObstructive sleep apnea (OSA) had a high prevalence in the population. Whether OSA increases the risk of amyotrophic lateral sclerosis (ALS) is unknown. Our aim was to clarify this issue using two-sample Mendelian randomization (MR) analysis in
Rongrong Du, Rongrong Du, Yahui Zhu, Yahui Zhu, Peng Chen, Peng Chen, Mao Li, Ying Zhang, Ying Zhang, Xusheng Huang, Xusheng Huang, Xusheng Huang   +11 more
doaj   +1 more source

Analysis of MMP2 promoter polymorphisms in childhood obesity

BMC Research Notes, 2011
Background Several lines of evidence suggest a possible functional role of Matrix metalloproteinase -2 (MMP-2) in obesity. The aim of this study was to evaluate the role of MMP-2 promoter polymorphisms in percentage body fat (PBF) as a measure of ...
Thompson John MD, Han Dug, Morgan Angharad R, Mitchell Edwin A, Ferguson Lynnette R   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Genetic Determinants of Circulating Sphingolipid Concentrations in European Populations [PDF]

, 2009
Sphingolipids have essential roles as structural components of cell membranes and in cell signalling, and disruption of their metabolism causes several diseases, with diverse neurological, psychiatric, and metabolic consequences.
S. Campbell, Aulchenko, Y.S. (Yurii), Igl, Wilmar,, Zaboli, Ghazal, Polasek, O. (Ozren), A. Wright, J. F. Wilson, Gyllensten, U, Hicks, Andrew A, Schwienbacher, C, Hengstenberg, Christian, I. R. König, Peter Ugocsai, A. Demirkan, C. Pattaro, Wichmann, H.-E., G. Liebisch, Peters, Annette, Kirichenko, Anatoly V, Liebisch, G, Peters, A. (Annette), Witteman, Jacqueline C. M., Wright, Alan, C. Hengstenberg, O. Polasek, König, Inke R, P. Ugocsai, Janssens, A. Cecilej W., Hayward, C., Campbell, Harry, Campbell, H, Pichler, I. (Irene), Pichler, I., Gerhard Liebisch, Demirkan, A., Campbell, S, Biloglav, Z. (Zrinka), P. P. Pramstaller, Kolcic, I, Johansson, Asa, Liebisch, Gerhard, C. M. van, Wichmann, H.E. (Heinz Erich), Janssens, A Cecilej W, Meitinger, T., Wild, SH, Ozren Polasek, Igl, W., Jeanette Erdmann, Schmitz, G, Franklin, CS, S. Schreiber, Jonasson, I, Wichmann, H-Erich, Ugocsai, P, Polsek, Ozren, Wichmann, H.-Erich, Cornelia M van Duijn, Hengstenberg, C, Erdmann, J. (Jeanette), H. Campbell, König, I.R. (Inke), Axenovich,T.I., G. Schmitz, Y. Aulchenko, S. H. Wild, Schreiber, Stefan, Gyllensten, Ulf,, Campbell, Harry; id_orcid, I. Rudan, G. Zaboli, Schreiber, S., Ivana Kolcic, Johansson, A, Wright, A, Franklin, Christopher S, Kolcic, I., Zorkoltseva, I.V. (Irina), Wilson, J.F., Rudan, I. (Igor), Johansson, A. (Åsa), Zorkoltseva, I.V., Schwienbacher, Christine, Duijn, Cornelia, Marroni, Fabio, Witteman, Jacqueline C M, Fabio Marroni, Zaboli, Ghazal,, Jonasson, Inger, Hicks, A.A. (Andrew), Irene Pichler, Gyllensten, U., Campbell, H., Wichmann, HE, A Cecilej W Janssens, Pramstaller, P.P. (Peter Paul), Janssens, A.C., Peters, A., Wild, S.H., Isaacs, A., Pichler, Irene, Vitart, Veronique, N. Hastie, Tatiana I Axenovich, Johansson, Åsa,, I. Kolcic, Ghazal Zaboli, James F Wilson, Kolcic, I. (Ivana), Wilson, James F; id_orcid, Biloglav, Zrinka, Ugocsai, P. (Peter), Gnewuch, C., A. Johansson, Zaboli, G., Marroni, F, Andrew A Hicks, Pattaro, C., Pichler, I, Christian Hengstenberg, Jacqueline C M Witteman, Schunkert, H, Biloglav, Z, Caroline Hayward, Pattaro, Cristian, C. Hayward, Koenig, Inke R., Zrinka Biloglav, Demirkan, A. (Ayşe), Liebisch, G., J. Erdmann, Franklin, C.S. (Christopher), I. V. Zorkoltseva, U. Gyllensten, Alan Wright, Pattaro, C, Franklin, Christopher S., Hengstenberg, C. (Christian), A. V. Kirichenko, Harry Campbell, Schunkert, H., W. Igl, Hastie, N., Ulf Gyllensten, C. Schwienbacher, Kirichenko, AV, Demirkan, Ayse, Janssens, A. CecileJ.W., Schreiber, S, Wild, S.H. (Sarah), Zorkoltseva, IV, Schwienbacher, C. (Christine), Erdmann, Jeanette, Yurii Aulchenko, Asa Johansson, Ben A Oostra, Aulchenko, Y., Veronique Vitart, Liebisch, G. (Gerhard), B. A. Oostra, Janssens, Cecile, Christine Schwienbacher, Hastie, N, A. C. W, Rudan, Igor, Igl, W. (Wilmar), I. Pichler, Erdmann, J., C. Gnewuch, Konig, IR, Anatoly V Kirichenko, Schwienbacher, C., van Duijn, C.M., Jonasson, I., Kirichenko, A.V. (Anatoly), Schmitz, G., Hicks, Andrew A., A. A. Hicks, Susan Campbell, Annette Peters, Gerd Schmitz, Hayward, Caroline, Zorkoltseva, Irina V, Witteman, JCM, T. I. Axenovich, Gnewuch, C, König, I.R., Carsten Gnewuch, H. Wichmann, Gyllensten, Ulf, Igl, Wilmar, Meitinger, T, Kirichenko, Anatoly V., H-Erich Wichmann, Cristian Pattaro, C. S. Franklin, Gnewuch, Carsten, König, Inke R., Isaacs, A.J. (Aaron), Erdmann, J, Zaboli, G. (Ghazal), Christopher S Franklin, Campbell, S., Irina V Zorkoltseva, Zorkoltseva, Irina V., Hengstenberg, C., Zaboli, G, Hicks, A.A., Peter P Pramstaller, Marroni, F. (Fabio), Sarah H Wild, Ayse Demirkan, Johansson, A., Wright, A., Hicks, AA, Wichmann, Heinz-Erich, Nick Hastie, Hastie, Nick, H. Schunkert, Polasek, Ozren, Janssens, A. Cecile J. W., Inger Jonasson, Axenovich, TI, Polasek, O., Peters, A, Oostra, Ben A., Oostra, B.A., Wright, A.F. (Alan), Axenovich, T.I. (Tatiana), van Duijn, Cornelia M., Heribert Schunkert, Vitart, V. (Veronique), Hastie, N. (Nick), Wild, Sarah H; id_orcid, Schmitz, Gerd, Hayward, C. (Caroline), Biloglav, Z., Schunkert, H. (Heribert), Campbell, S. (Susan), A. Peters, Ugocsai, Peter, T. Meitinger, Oostra, Ben, Inke R König, Kolcic, Ivana, Stefan Schreiber, Gibson, Greg, Schunkert, Heribert, Z. Biloglav, Rudan, I., Isaacs, Aaron, V. Vitart, Tikka-Kleemola, P. (Päivi), Wilson, JF, Oostra, B.A. (Ben), Franklin, C.S., Jonasson, I. (Inger), Wilson, James F., Schreiber, S. (Stefan), Pramstaller, Peter P, Rudan, I, Wild, Sarah H., Schmitz, G. (Gerd), Janssens, A.C.J.W. (Cécile), Oostra, Ben A, Vitart, V, Meitinger, Thomas, Vitart, V., Aulchenko, Yurii, Pramstaller, PP, Gnewuch, C. (Carsten), Marroni, F., Campbell, Susan, Axenovich, Tatiana I., Hayward, C, Witteman, J.C.M. (Jacqueline), J. C. M, Wilmar Igl, Igl, W, Axenovich, Tatiana I, Kirichenko, A.V., Aulchenko, Yuriy, Wilson, J.F. (James), Gyllensten, U. (Ulf), van Duijn, Cornelia M, Meitinger, T. (Thomas), Hayward, Caroline; id_orcid, Thomas Meitinger, Ugocsai, P., Pattaro, C. (Cristian), Polasek, O, I. Jonasson, Pramstaller, Peter P., Aaron Isaacs, Igor Rudan, Witteman, J.C., Jonasson, Inger,, A. Isaacs, Pramstaller, P.P.   +298 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source