Results 211 to 220 of about 1,122,121 (342)

Genetic alterations in early-onset invasive breast carcinomas: Correlation of c-erbB-2 amplification detected by fluorescenceIn situ hybridization with p53 accumulation and tumor phenotype [PDF]

, 1999
Maryse Fiche, Hervé Avet‐Loiseau, Marie‐Françoise Heymann, Frédéric Moussaly, Christine Digabel, Madeleine Joubert, Jean‐Marc Classe, F. Dravet, P. Fumoleau, Jeffrey S. Ross, Christine M. Maugard   +10 more
openalex   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

A case of Beauveria bassiana keratitis confirmed by internal transcribed spacer and LSU rDNA D1–D2 sequencing

New Microbes and New Infections, EarlyView., 2014
Abstract We describe a case of fungal keratitis due to Beauveria bassiana in a farmer with Fuchs' dystrophy, treated with amphotericin B. Surgery with penetrating keratoplasty was necessary to resolve the lesions. Susceptibility testing and molecular sequencing permitted the identification and treatment of this rare aetiological agent of invasive ...
M. Ligozzi, L. Maccacaro, M. Passilongo, E. Pedrotti, G. Marchini, R. Koncan, G. Cornaglia, A. R. Centonze, G. Lo Cascio   +8 more
wiley   +1 more source

Clinico-radiological findings of men 2A syndrome and its genetic correlation: A case report with review of literature. [PDF]

Radiol Case Rep
Singhal N, Shukla S, Mishra N, Sherwani P, Babu J.   +4 more
europepmc   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Leisure-Time Physical Activity, Sedentary Behavior, and Biological Aging: Evidence From Genetic Correlation and Mendelian Randomization Analyses. [PDF]

Scand J Med Sci Sports
Zhao X, Wu X, He L, Xiao J, Xiang R, Sha L, Tang M, Hao Y, Qu Y, Xiao C, Qin C, Hou J, Deng Q, Zhu J, Zheng S, Zhou J, Yu T, Yang B, Song X, Han T, Liao J, Zhang T, Fan M, Li J, Jiang X.   +24 more
europepmc   +1 more source

GENETIC PARAMETERS, CORRELATIONS AND PATH ANALYSIS AMONG YIELD AND YIELD CHARACTERS IN GRAIN SORGHUM [PDF]

, 1996
R SANKARAPANDIAN, D KRISHNADOSS, AMIRTHA DEVARATHINAM A   +2 more
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Cathepsins and Skin Cancer (Malignant Melanoma, Basal Cell Carcinoma, and Squamous Cell Carcinoma): Insight From Genetic Correlation and Mendelian Randomization. [PDF]

Clin Cosmet Investig Dermatol
Li X, Yang S, Du Z, Xie W, Zhu M, Han L, Zhou Q.   +6 more
europepmc   +1 more source

THE ECOLOGY AND GENETICS OF FITNESS IN CHLAMYDOMONAS. X. THE RELATIONSHIP BETWEEN GENETIC CORRELATION AND GENETIC DISTANCE [PDF]

, 2000
Rees Kassen, Graham Bell
openalex   +1 more source