JointPRS: A data-adaptive framework for multi-population genetic risk prediction incorporating genetic correlation. [PDF]
Xu L+6 more
europepmc +1 more source
FACTORS AFFECTING THE GENETIC LOAD IN DROSOPHILA: SYNERGISTIC EPISTASIS AND CORRELATIONS AMONG FITNESS COMPONENTS [PDF]
Michael C. Whitlock, Denis Bourguet
openalex +1 more source
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla+15 more
wiley +1 more source
Exploring the molecular basis of the genetic correlation between body mass index and brain morphological traits. [PDF]
Fusco D+7 more
europepmc +1 more source
Negative genetic correlation between traits of the Drosophila head, and interspecific divergence in head shape [PDF]
Fabian M. Norry+2 more
openalex +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici+8 more
wiley +1 more source
Is There a Genetic Correlation Between General Factors of Intelligence and Personality?
J. Loehlin+6 more
semanticscholar +1 more source
Biomolecular Characterization of <i>Trichomonas vaginalis</i> from Spain: Evaluating Genetic Correlation with Drug Resistance and Endobionts. [PDF]
Ibáñez-Escribano A+3 more
europepmc +1 more source