Results 41 to 50 of about 32,098 (126)

Reminiscences on the honeybee genome project and the rise of epigenetic concepts in insect science

Insect Molecular Biology, Volume 33, Issue 5, Page 444-456, October 2024.
The honeybee genome project was an important milestone in social insect research that opened new possibilities for the community's quest to study social evolution at molecular and cellular levels. Among new lines of research, the epigenomic modifications to DNA, histones and RNAs gained special prominence as potential drivers of phenotypic and ...
Ryszard Maleszka
wiley   +1 more source

Man and embryo: Historicizing ideas about humanity in the study of reproduction, 18th–19th centuries

Sociology Lens, Volume 37, Issue 3, Page 329-347, September 2024.
Abstract This article is concerned with historicizing the idea that all people belong to a single collective of biological human beings. It analyzes implications and changes in the concept of “Man” over the 18th and 19th centuries, particularly in the study of reproduction and embryos.
Chiara Lacroix
wiley   +1 more source

Ion Channel Dysregulation in Neurodevelopmental Disorders: Mechanisms, Models, and Therapeutic Advances

Frontiers in Bioscience-Landmark
Ion channels are fundamental to neuronal excitability, synaptic transmission, and the coordinated development of brain circuits. Disruptions in their function—collectively termed ion channelopathies—have emerged as central mechanisms underlying a broad ...
Zihan Shi, Shanshan Li, Xin Jin
doaj   +1 more source

EEG functional connectivity as a Riemannian mediator: An application to malnutrition and cognition

Human Brain Mapping, Volume 45, Issue 7, May 2024.
This study introduces a novel mediation analysis approach using EEG cross‐spectra to investigate whether malnourishment affects children's cognitive performance. The results indicate that brain function across delta, theta, alpha, and beta band frequencies mediates the impact of malnourishment on cognitive performance in specific brain regions ...
Carlos Lopez Naranjo, Fuleah Abdul Razzaq, Min Li, Ying Wang, Jorge F. Bosch‐Bayard, Martin A. Lindquist, Anisleidy Gonzalez Mitjans, Ronaldo Garcia, Arielle G. Rabinowitz, Simon G. Anderson, Giuseppe A. Chiarenza, Ana Calzada‐Reyes, Trinidad Virues‐Alba, Janina R. Galler, Ludovico Minati, Maria L. Bringas Vega, Pedro A. Valdes‐Sosa   +16 more
wiley   +1 more source

Abnormal methylation mediated upregulation of LINC00857 boosts malignant progression of lung adenocarcinoma by modulating the miR‐486‐5p/NEK2 axis

The Clinical Respiratory Journal, Volume 18, Issue 5, May 2024.
Low methylation of LINC00857 in the promoter region led to its high expression. Knockdown of LINC00857 restrained lymph node metastasis and stimulated radiosensitivity of LUAD cells. LINC00857 acted as a ceRNA, regulating NEK2 expression by binding to miR‐486‐5p.
Haoyu Fu, Mingming Zhang, Xiaohui Liu, Yiming Yang, Ying Xing   +4 more
wiley   +1 more source

Epigenetic associations of GPNMB rs199347 variant with alcohol consumption in Parkinson’s disease

Frontiers in Psychiatry
IntroductionAlcohol consumption can induce a neuroinflammatory response and contribute to the progression of neurodegeneration. However, its association with Parkinson’s disease (PD), the second most common neurodegenerative disorder, remains ...
Yen-Chung Chen, Yen-Chung Chen, Yi-Chia Liaw, Oswald Ndi Nfor, Chih-Hsuan Hsiao, Ji-Han Zhong, Shey-Lin Wu, Shey-Lin Wu, Yung-Po Liaw, Yung-Po Liaw, Yung-Po Liaw   +10 more
doaj   +1 more source

Interplay between the HPA axis and inflammation as mechanisms therapeutic targets of Cannabis sativa in depression

Frontiers in Pharmacology
Major Depressive Disorder (MDD) is a highly prevalent and disabling psychiatric disorder, representing a major global health burden across all age groups. Increasing evidence indicates that its pathophysiology involves a complex interplay between chronic
Fernanda Pilatti, Marieli Philippsen, Amanda Gollo Bertollo, Cleneide Picinin Webler, Alessandra Kozelinski Bordignon, Zuleide Maria Ignácio   +5 more
doaj   +1 more source

An Evolutionary Preamble Towards a Multilevel Framework to Understand Adolescent Mental Health: An International Delphi Study

Children
Background/Objectives: Adolescence is a sensitive developmental window shaped by both vulnerabilities and adaptive potential. From an evolutionary standpoint, mental health difficulties in this period may represent functional responses to environmental ...
Federica Sancassiani, Vanessa Barrui, Fabrizio Bert, Sara Carucci, Fatma Charfi, Giulia Cossu, Arne Holte, Jutta Lindert, Simone Marchini, Alessandra Perra, Samantha Pinna, Antonio Egidio Nardi, Alessandra Scano, Cesar A. Soutullo, Massimo Tusconi, Diego Primavera   +15 more
doaj   +1 more source

Schizophrenia, genetics, epigenesis, environment: a systematic review of unifi ed etiological hypotheses and genetic profi le; and a new algorithm to cope with the main fi ndings

, 2010
Contexto: la esquizofrenia es un síndrome complejo relacionado con genes y factores de riesgo no genéticos. Estudios epidemiológicos reconocidos reportan su presencia en todas las culturas y regiones geográficas. En este sentido, las Hipótesis Etiológicas Unificadas enfrentan simultáneamente el desafío de presentar los datos experimentales y demostrar ...
Machado Dias, Alvaro, Luiz Rodriguez, E. Avelino   +1 more
openaire   +1 more source

Husserl, Rahner, and Their Transcendental(S): Transcendentality, Intersubjectivity, and Original Sin

The Heythrop Journal, Volume 65, Issue 5, Page 552-566, September 2024.
Carl Scerri
wiley   +1 more source