Results 31 to 40 of about 35,945 (165)

Crossovers between epigenesis and epigenetics. A multicenter approach to the history of epigenetics (1901-1975) [PDF]

, 2014
The origin of epigenetics has been traditionally traced back to Conrad Hal Waddington's foundational work in 1940s. The aim of the present paper is to reveal a hidden history of epigenetics, by means of a multicenter approach.
Costa, R., Frezza, G.
core  

Social epigenetics: a science of social science? [PDF]

, 2016
Epigenetics has considerable potential to transform social science by embedding mutually regulative reciprocal connections between biological and social processes within the human activities it studies. This paper highlights common epigenetic methods and
Bagot, Bowker, Brown, Busch, Cacabelos, Cederstrom, Cromby, Cromby, Daray, Gilbert, Gilbert, Gottlieb, Heerwagen, Hoffmann, Jablonka, Joseph, Juengst, Kirchheiner, Kleinman, Kringlen, Landecker, Landecker, Loke, Meloni, Meloni, Newton, Niewohner, Papadopoulos, Papadopoulos, Papadopoulos, Rose, Rosenbaum, Spauwen, Spector, Stephenson, Szyf, Waddington, Yehuda, Zandi, Zhang, Zhang   +40 more
core   +3 more sources

A Systematic Review of Adverse Childhood Experiences and Epigenetic Age Acceleration in Later Adult Life Measured With Second and Third‐Generation Epigenetic Clocks

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 4, Page 270-290, June 2026.
ABSTRACT We examined the relationship between adverse childhood experiences (ACEs) and epigenetic age acceleration (EAA) in adulthood as measured by second and third generation epigenetic clocks by performing a systematic review of the literature. The electronic databases MEDLINE and EMBASE were searched on 17 July 2023.
Matthew Green, Laura Horsfall, Azam Saied   +2 more
wiley   +1 more source

Phenotypic Diversity of Marfan Syndrome

JACC: Advances
Marfan syndrome (MFS) is a genetic disorder primarily impacting the cardiovascular system, eyes, and skeletal structure, with its root cause being mutations in the FBN1 gene.
Zixiang Xu, MD, Zhenghong Li, MD, Long Xiang, MD, Tao Chen, MD, Wang Lu, MD, Chang’e Guo, MD, Jinmiao Chen, MD, PhD, Bi’ang Kang, MD, PhD, Zesi Liu, MD, Daokang Xiang, MD, PhD, Liqun Sun, MD, PhD, Kui Hu, MD, PhD   +11 more
doaj   +1 more source

Developmental Systems Theory as a Process Theory [PDF]

, 2018
Griffiths and Russell D. Gray (1994, 1997, 2001) have argued that the fundamental unit of analysis in developmental systems theory should be a process – the life cycle – and not a set of developmental resources and interactions between those resources ...
Griffiths, Paul Edmund, Stotz, Karola
core  

Epigenetics—Innovations and Misconceptions

Natural Sciences, Volume 6, Issue 2, April 2026.
ABSTRACT Epigenetics is a scientific field whose definition has changed over time. Established in the 1940s by C.H. Waddington by synthesis from embryology and genetics, the term “epigenetics” is now mainly used to describe the role of chromatin modifications in the regulation and perpetuation of gene activity states.
Bernhard Horsthemke
wiley   +1 more source

Immune and inflammatory mechanisms in asthma: insights into epigenetic modifications

Frontiers in Immunology
BackgroundAsthma is a chronic respiratory disease influenced by genetic and environmental factors. Emerging evidence highlights epigenetics as a key regulatory mechanism in asthma development.ObjectiveThis research aimed to summarize current evidence on ...
Haixia Fan, Bomeng Zhao, Huiyan Niu, Yan Li, Lu Zhai, Limantian Wang, Shudan Deng, Jie Gao, Xiaoling Gao   +8 more
doaj   +1 more source

Differential expression of conserved germ line markers and delayed segregation of male and female primordial germ cells in a hermaphrodite, the leech helobdella. [PDF]

, 2013
In sexually reproducing animals, primordial germ cells (PGCs) are often set aside early in embryogenesis, a strategy that minimizes the risk of genomic damage associated with replication and mitosis during the cell cycle.
Cho, Sung-Jin, Vallès, Yvonne, WEISBLAT, David A.   +2 more
core   +2 more sources

A Conceptual Approach to Complex Model Management with Generalized Modelling Patterns and Evolutionary Identification

, 2018
Complex systems' modeling and simulation are powerful ways to investigate a multitude of natural phenomena providing extended knowledge on their structure and behavior.
Bochenina, Klavdiya O., Funkner, Anastasia A., Kalyuzhnaya, Anna V., Kisliakovskii, Ilia O., Kovalchuk, Sergey V., Metsker, Oleg G., Nikitin, Nikolay O., Vaganov, Danila A.   +7 more
core   +1 more source

Associations of Skin Biomechanical Properties With Biological Aging Clocks and Longitudinal Changes in Intrinsic Capacity in Adults Aged 20–93: The INSPIRE‐T Project

Aging Cell, Volume 24, Issue 10, October 2025.
This study assessed skin biomechanics using the Cutometer in 441 community‐dwelling adults aged 20–93 from the INSPIRE‐T cohort. We demonstrated that skin elasticity and viscoelasticity parameters were associated with the intrinsic capacity (IC) score, a functional marker of healthy aging encompassing cognition, locomotion, psychology, vitality, and ...
Wan‐Hsuan Lu, Sophie Guyonnet, Jérémy Raffin, Sandrine Bessou‐Touya, Katia Ravard Helffer, Pascale Bianchi, Jimmy Le Digabel, Paul Bensadoun, Jean‐Marc Lemaitre, Philipe de Souto Barreto, Bruno Vellas, the IHU HealthAge INSPIRE/Open Science study group, Sophie Guyonnet, Bruno Vellas, Lauréane Brigitte, Agathe Milhet, Elodie Paez, Emeline Muller, Sabine Le Floch, Catherine Takeda, Catherine Faisant, Françoise Lala, Gabor Abellan Van Kan, Zara Steinmeyer, Antoine Piau, Tony Macaron, Davide Angioni, Pierre‐Jean Ousset, Mélanie Comté, Nathalie Daniaud, Fanny Boissou‐Parachaud, Sandrine Andrieu, Christelle Cantet, Yves Rolland, Philipe de Souto Barreto, Fabien Pillard, Bernard Teysseyre, Marie Faruch, Pierre Payoux, Catherine Takeda, Neda Tavassoli, Marie Dorard, Bénédicte Razat, Camille Champigny, Sophie Guyonnet, Cédric Dray, Jean‐Philippe Pradère, Angelo Parini, Yohan Santin, Dominique Langin, Pierre Gourdy, Laurent O. Martinez, Anne Bouloumié, Angelo Parini, Nicolas Fazilleau, Roland Liblau, Jean‐Charles Guéry, Michel Simon, Nicolas Gaudenzio, Luciana Bostan, Hicham El Costa, Nabila Jabrane Ferrat, Philippe Valet, Cedric Dray, Isabelle Ader, Valérie Planat, Louis Casteilla, Pierre Payoux, Patrice Peran, Cyrille Delpierre, Sandrine Andrieu, Claire Rampon, Noelie Davezac, Bruno Guiard, Nathalie Vergnolle, Jean‐Paul Motta, Sara Djebali, Pauline Floch, Céline Deraison, Chrystelle Bonnart, Jean‐Emmanuel Sarry, Nicola Coley, Sophie Guyonnet, Christelle Cantet, Jessica Pontary, Sandrine Andrieu   +85 more
wiley   +1 more source