Results 81 to 90 of about 492,575 (295)

Comparison of Different Types of Fitness Functions to Choose the Appropriate Attributes for Porosity Prediction

مجلة النهرين للعلوم الهندسية, 2017
Porosity is one of the most important reservoir characteristics because it indicates to fluid collection. Several techniques used to get good porosity prediction, so, in this study we employed seismic attributes and well log data in a genetic algorithm ...
Muna Hadi Saleh, Hadeel M. Tuama
doaj  

Improved Genetic Algorithm to Reduce Mutation Testing Cost

IEEE Access, 2017
Mutation testing is a fault-based testing technique that helps generating effective test cases. Mutation testing is computationally expensive, because it requires executing hundreds and even thousands of mutants.
Muhammad Bilal Bashir, Aamer Nadeem
doaj   +1 more source

Fitness peaks of dengue virus populations. [PDF]

PLoS ONE, 2018
The role of intra-host genetic diversity in dengue viral populations remains a topic of debate, particularly the impact on transmission of changes in this diversity. Several approaches have been taken to increasing and decreasing the genetic diversity of
Wen Jun Liu, John G Aaskov
doaj   +1 more source

Spontaneous mutation accumulation in multiple strains of the green alga, Chlamydomonas reinhardtii [PDF]

, 2014
Estimates of mutational parameters, such as the average fitness effect of a new mutation and the rate at which new genetic variation for fitness is created by mutation, are important for the understanding of many biological processes. However, the causes
Adams, Baer, Baer, Baranyi, Barrick, Bateman, Charlesworth, Charlesworth, Crutchfield, Davies, Dickinson, Drake, Fernandez, Fisher, Fry, García-Dorado, Goffeau, Goho, Gong, Haerty, Halligan, Halligan, Hartfield, Joseph, Keightley, Keightley, Keightley, Keightley, Keightley, Keightley, Kibota, Knight, Kondrashov, Koonin, Liss, Loewe, Lukjancenko, Lynch, Lynch, Lynch, Lynch, Massey, Matic, Merchant, Mukai, Mukai, Ness, Otto, R Core Team, Schaack, Schoen, Schrider, Schultz, Sharp, Shaw, Smith, Sokal, Sousa, Sundin, Sung, The Arabadopsis, The C. elegans Sequencing Consortium, Torgerson, Winzeler, Zeyl, Zuur   +65 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

A Field Guide to Genetic Programming [PDF]

, 2008
xiv, 233 p. : il. ; 23 cm.Libro ElectrónicoA Field Guide to Genetic Programming (ISBN 978-1-4092-0073-4) is an introduction to genetic programming (GP).
Langdon, William B., McPhee, Nicholas F., Poli, Ricardo   +2 more
core  

Selection, inheritance, and the evolution of parent-offspring interactions

, 2004
Very few studies have examined parent-offspring interactions from a quantitative genetic perspective. We used a cross-fostering design and measured genetic correlations and components of social selection arising from two parental and two offspring ...
Lock, Judith E., Moore, Allen J., Smiseth, Per T.   +2 more
core   +1 more source

Competent genetic-evolutionary optimization of water distribution systems [PDF]

, 2001
A genetic algorithm has been applied to the optimal design and rehabilitation of a water distribution system. Many of the previous applications have been limited to small water distribution systems, where the computer time used for solving the problem ...
Simpson, A., Wu, Z.
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Genetic variation and hybridization determine the outcomes of conservation reintroductions

Conservation Letters
The preservation of genetic variation is fundamental in biodiversity conservation, yet its importance for population viability remains contentious.
Colter A. Feuerstein, Ryan P. Kovach, Carter G. Kruse, Matt E. Jaeger, Donovan A. Bell, Zachary L. Robinson, Andrew R. Whiteley   +6 more
doaj   +1 more source