Results 11 to 20 of about 483,969 (264)

Interleukin-10 gene polymorphism in patients with systemic lupus erythematosus and normal individuals of Kasakh population

open access: yesНаучно-практическая ревматология, 2003
An analysis of interleukin-10 (IL-10) gene polymorphism associative link with clinical variability in Kasakhs. 49 pts with systemic lupus erythematosus were included (48 female and I male).
Z E Omarbekova   +3 more
doaj   +1 more source

Genetic Heterogeneity of Cebocephaly [PDF]

open access: yesJournal of Medical Genetics, 1974
Three infants with cebocephaly with entirely different aetiologies are described: one possibly representing the effect of a single mutant gene, one with apparent E trisomy, and one with D trisomy. In comparison with other reported patients, it is likely that infants with cebocephaly and no associated chromosomal abnormality have few, if any ...
L B, Holmes, S, Driscoll, L, Atkins
openaire   +2 more sources

Intrapatient genomic divergence across multiple primary tumors in young Korean patients [PDF]

open access: yesKorean Journal of Clinical Oncology
Purpose Multiple primary tumors arising in the same individual pose challenges for precision oncology, particularly in the context of hereditary cancer syndromes such as Lynch syndrome.
Yoon Young Choi
doaj   +1 more source

Current status of accelerated corneal cross-linking

open access: yesIndian Journal of Ophthalmology, 2013
Corneal cross-linking with riboflavin is a technique to stabilize or reduce corneal ectasia, in diseases such as keratoconus and post-laser-assisted in situ keratomileusis (LASIK) ectasia.
Michael Mrochen
doaj   +1 more source

Clinical implications of the molecular biology of prostate cancer: Review article

open access: yesRevista de la Facultad de Medicina Humana, 2022
To understand the term genomic heterogeneity in prostate cancer, we must understand the clonal genomic evolution of cancer, as well as knowing that it is a dynamic and evolutionary phenomenon.
María del Carmen Castro-Mujica
doaj   +1 more source

Topography-guided custom ablation treatment for treatment of keratoconus

open access: yesIndian Journal of Ophthalmology, 2013
Keratoconus is a progressive ectatic disorder of the cornea which often presents with fluctuating refraction and high irregular astigmatism. Correcting the vision of these patients is often a challenge because glasses are unable to correct the irregular ...
Rohit Shetty   +3 more
doaj   +1 more source

Bovine nebovirus infection (review)

open access: yesВетеринария сегодня, 2023
Animal husbandry is one of the main agricultural industries in most countries over the world as well as in the Russian Federation, and its profitability is determined by three main factors: the animal genetic potential, complete diet and freedom from ...
V. A. Mischenko   +4 more
doaj   +1 more source

Genetic conflicts and intercellular heterogeneity [PDF]

open access: yesJournal of Evolutionary Biology, 2004
Adaptation is what elevates biology above mere chemistry and physics, and the salient feature of adaptation is that it is generally associated with individual organisms. The edge of an organism is a crucial boundary, within which we generally find adaptive cooperation and outside of which we find competition and conflict.
J E, Strassmann, D C, Queller
openaire   +2 more sources

Resolving genetic heterogeneity in cancer [PDF]

open access: yesNature Reviews Genetics, 2019
To a large extent, cancer conforms to evolutionary rules defined by the rates at which clones mutate, adapt and grow. Next-generation sequencing has provided a snapshot of the genetic landscape of most cancer types, and cancer genomics approaches are driving new insights into cancer evolutionary patterns in time and space.
Samra Turajlic   +3 more
openaire   +3 more sources

Rejection of immunogenic tumor clones is limited by clonal fraction

open access: yeseLife, 2018
Tumors often co-exist with T cells that recognize somatically mutated peptides presented by cancer cells on major histocompatibility complex I (MHC-I). However, it is unknown why the immune system fails to eliminate immune-recognizable neoplasms before ...
Ron S Gejman   +6 more
doaj   +1 more source

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