Results 151 to 160 of about 1,161,989 (268)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Genetic Identification of Lamprey Genera and Anadromous Ecotypes in Watersheds of the Northeastern Pacific Ocean. [PDF]

Evol Appl
Silver GS, Lampman RT, Percival N, Timoshevskaya N, Smith JJ, Bentley KT, Wade J, Narum SR, Hess JE.   +8 more
europepmc   +1 more source

Genetic identification of preoptic neurons that regulate body temperature in mice. [PDF]

Temperature (Austin), 2022
Machado NLS, Saper CB.
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Genetic identification of gastrointestinal parasites in the world's most endangered ungulate, the hirola (Beatragus hunteri). [PDF]

Vet Rec
Remesar S, García-Dios D, Forcina G, Ali AH, Ndunda M, Jowers MJ.   +5 more
europepmc   +1 more source

Systems Genetic Identification of Mitochondrion-Associated Alzheimer's Disease Genes and Implications for Disease Risk Prediction. [PDF]

Biomedicines, 2022
Xu X, Xu X, Wang H, Bennett DA, Zhang QY, Wang G, Zhang HY.   +6 more
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

First case of Trichophyton indotineae in Brazil: clinical and mycological criteria and genetic identification of terbinafine resistance. [PDF]

An Bras Dermatol
Veasey JV, Gonçalves RDJ, Valinoto GCJ, Carvalho GSM, Celestrino GA, Reis APC, Lima APC, Costa ACD, Melhem MSC, Benard G, Sousa MGT.   +10 more
europepmc   +1 more source

First Molecular Identification of Fasciola gigantica in Slaughtered Cattle in Cape Verde: Prevalence, Gross Pathological Lesions, Genetic Identification and Coprological Analysis. [PDF]

Pathogens, 2023
Levy S, Calado M, Mateus TL, Vieira-Pinto M.   +3 more
europepmc   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source