Results 161 to 170 of about 2,342,497 (308)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

A computational approach for positive genetic identification and relatedness detection from low-coverage shotgun sequencing data. [PDF]

J Hered, 2023
Nguyen R, Kapp JD, Sacco S, Myers SP, Green RE.   +4 more
europepmc   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Genetic identification of Pid3-1 and its regulatory role in promoting blast resistance in rice. [PDF]

G3 (Bethesda)
Liu J, He N, Cheng Z, Lin S, Fu S, Wang M, Huang F, Abou-Elwafa SF, Al Aboud NM, Huang C, Yang D.   +10 more
europepmc   +1 more source

Morphological, acoustic and genetic identification of a reproducing population of the invasive African clawed frog Xenopuslaevis (Anura, Pipidae) recently discovered in Belgium. [PDF]

Zookeys, 2023
Pauwels OSG, Brecko J, Baeghe D, Venderickx J, Vanderheyden A, Backeljau T.   +5 more
europepmc   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Genetic identification of mouse trigeminal afferents responsible for mechanical allodynia. [PDF]

Cell Rep
Li T, Son H, Arora V, Shannonhouse J, Kumari S, Chang D, Caterina M, Kim YS, Chung MK.   +8 more
europepmc   +1 more source

Mid-Infrared Photothermal-Fluorescence In Situ Hybridization for Functional Analysis and Genetic Identification of Single Cells. [PDF]

Anal Chem, 2023
Bai Y, Guo Z, Pereira FC, Wagner M, Cheng JX.   +4 more
europepmc   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Genetic identification of the selenate reductase in <i>Enterobacter cloacae</i> SLD1a-1. [PDF]

Appl Environ Microbiol
Phan J, Klein D, Nanda V, Zylstra G, Yee N.   +4 more
europepmc   +1 more source