Results 221 to 230 of about 7,102,789 (361)

Mid-Infrared Photothermal-Fluorescence In Situ Hybridization for Functional Analysis and Genetic Identification of Single Cells. [PDF]

Anal Chem, 2023
Bai Y, Guo Z, Pereira FC, Wagner M, Cheng JX.   +4 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Genetic identification of the selenate reductase in <i>Enterobacter cloacae</i> SLD1a-1. [PDF]

Appl Environ Microbiol
Phan J, Klein D, Nanda V, Zylstra G, Yee N.   +4 more
europepmc   +1 more source

Genetic identification and reiterated captures suggest that the <i>Astyanax mexicanus</i> El Pachón cavefish population is closed and declining. [PDF]

Zool Res, 2023
Legendre L, Rode J, Germon I, Pavie M, Quiviger C, Policarpo M, Leclercq J, Père S, Fumey J, Hyacinthe C, Ornelas-García P, Espinasa L, Rétaux S, Casane D.   +13 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Genetic identification of mutations and MLST types associated with decreased susceptibility to ceftriaxone in <i>Neisseria gonorrhoeae</i>. [PDF]

Front Microbiol
Zhang X, Wang H, Gu Y, Chen X, Zhou G, Liu C, Ji L, Xie R, Zhang J, Shao Z, Zhang M.   +10 more
europepmc   +1 more source

First Detection and Genetic Identification of Wolbachia Endosymbiont in Field-Caught Aedes aegypti (Diptera: Culicidae) Mosquitoes Collected from Southern Taiwan. [PDF]

Microorganisms, 2023
Chao LL, Shih CM.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Genetic identification and characterization of putatively novel, stable, and validated loci for plant height in wheat (Triticum aestivum L.). [PDF]

BMC Genomics
Yao Q, Chen B, Lohani MN, Chen Q, Wang T, Chen J, Wang C, Zhang H, Lu L, Habib A, Ma J, Xie Q.   +11 more
europepmc   +1 more source

Genetic identification of bat species for pathogen surveillance across France. [PDF]

PLoS One, 2022
Arnaout Y, Djelouadji Z, Robardet E, Cappelle J, Cliquet F, Touzalin F, Jimenez G, Hurstel S, Borel C, Picard-Meyer E.   +9 more
europepmc   +1 more source