Results 231 to 240 of about 7,102,789 (361)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Bone Type Selection for Human Molecular Genetic Identification of Skeletal Remains. [PDF]

Genes (Basel)
Inkret J, Zupanič Pajnič I.
europepmc   +1 more source

Genetic identification of tissues and cell types underlying attention-deficit/hyperactivity disorder. [PDF]

Front Psychiatry, 2022
Wei WQ, Sun H, Chen YJ, Liu XW, Zhou R, Li Y, Liu XW.   +6 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Identification of Synonymous Genetic Variants Associated with Idiopathic Thrombosis using whole exome sequencing [PDF]

The etiology of substantial number of thrombosis cases remains undetermined. Sequencing and comprehensive analysis of the entire exome in patients with idiopathic thrombosis enable the identification of novel gene variants potentially significant for ...
Mitić, Martina Mia, Ušjak, Dušan, Đorđević, Valentina, Kovač, Mirjana, Dunjić Manevski, Sofija, Tomić, Branko, Cumbo, Marija   +6 more
core  

Genetic identification of undiagnosed benign ethnic neutropenia in patients receiving clozapine treatment. [PDF]

Br J Psychiatry
Aziri H, Vallianatou K, Balgobin B, Taylor D.   +3 more
europepmc   +1 more source

Genetic identification of preoptic neurons that regulate body temperature in mice. [PDF]

Temperature (Austin), 2022
Machado NLS, Saper CB.
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Genetic Identification of Lamprey Genera and Anadromous Ecotypes in Watersheds of the Northeastern Pacific Ocean. [PDF]

Evol Appl
Silver GS, Lampman RT, Percival N, Timoshevskaya N, Smith JJ, Bentley KT, Wade J, Narum SR, Hess JE.   +8 more
europepmc   +1 more source

Systems Genetic Identification of Mitochondrion-Associated Alzheimer's Disease Genes and Implications for Disease Risk Prediction. [PDF]

Biomedicines, 2022
Xu X, Xu X, Wang H, Bennett DA, Zhang QY, Wang G, Zhang HY.   +6 more
europepmc   +1 more source