Results 51 to 60 of about 628,301 (302)

Feline Polycystic Kidney Disease: An Update

Veterinary Sciences, 2021
Polycystic kidney disease (PKD) is a disease that affects felines and other mammals, such as humans. The common name is autosomal dominant polycystic kidney disease (ADPKD) and causes a progressive development of fluid-filled cysts in the kidney and ...
Lorie Schirrer, Pablo Jesús Marín-García, Lola Llobat   +2 more
doaj   +1 more source

Phenotype standardization for drug-induced kidney disease. [PDF]

, 2015
Drug-induced kidney disease is a frequent cause of renal dysfunction; however, there are no standards to identify and characterize the spectrum of these disorders.
Awdishu, Linda, Cerda, Jorge, Chakaravarthi, Raj, Davenport, Andrew, Goldstein, Stuart L, Holden, Arthur L, Macedo, Etienne, Mehta, Ravindra L, Murray, Patrick T   +8 more
core   +2 more sources

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Review of childhood genetic nephrolithiasis and nephrocalcinosis

Frontiers in Genetics
Nephrolithiasis (NL) is a common condition worldwide. The incidence of NL and nephrocalcinosis (NC) has been increasing, along with their associated morbidity and economic burden.
Ashley M. Gefen, Joshua J. Zaritsky
doaj   +1 more source

The HIDDEN Protocol: An Australian Prospective Cohort Study to Determine the Utility of Whole Genome Sequencing in Kidney Failure of Unknown Aetiology

Frontiers in Medicine, 2022
Early identification of genetic kidney disease allows personalised management, clarification of risk for relatives, and guidance for family planning. Genetic disease is underdiagnosed, and recognition of genetic disease is particularly challenging in ...
Jacqueline Soraru, Sadia Jahan, Sadia Jahan, Catherine Quinlan, Catherine Quinlan, Catherine Quinlan, Catherine Quinlan, Cas Simons, Cas Simons, Louise Wardrop, Louise Wardrop, Rosie O’Shea, Rosie O’Shea, Alasdair Wood, Alasdair Wood, Amali Mallawaarachchi, Amali Mallawaarachchi, Amali Mallawaarachchi, Chirag Patel, Chirag Patel, Zornitza Stark, Zornitza Stark, Zornitza Stark, Andrew John Mallett, Andrew John Mallett, Andrew John Mallett, Andrew John Mallett, Andrew John Mallett   +27 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Prenatal Diagnosis of Autosomal Dominant Polycystic Kidney Disease: Case Report

Reports
Background and Clinical Significance: Polycystic kidney disease (PKD) is the most common inherited kidney condition, affecting approximately 500,000 individuals in the US.
Elitsa Gyokova, Eleonora Hristova-Atanasova, Elizabeth Odumosu, Antonia Andreeva   +3 more
doaj   +1 more source

Case report: Genotype-phenotype characteristics of nine novel PKD1 mutations in eight Chinese patients with autosomal dominant polycystic kidney disease

Frontiers in Medicine, 2023
IntroductionAutosomal dominant polycystic kidney disease (ADPKD) is a common genetic disorder. The PKD1 gene is responsible for the majority of ADPKD cases, and the mutations in this gene exhibit high genetic diversity.
Jing Zhuang, Ailima Aierken, Dilina Yalikun, Jun Zhang, Xiaoqin Wang, Yongfang Ren, Xuefei Tian, Hong Jiang   +7 more
doaj   +1 more source

Macrophages and Galectin 3 Control Bacterial Burden in Acute and Subacute Murine Leptospirosis That Determines Chronic Kidney Fibrosis [PDF]

, 2018
Previous studies have suggested that macrophages may contribute to acute Leptospira dissemination, as well as having a major role in kidney fibrosis. Our aim was to characterize the role of macrophages and galectin 3 (Gal-3) on the survival, clinical ...
Carrera Silva, Eugenio Antonio, Charó, Nancy Lorena, Drut, Ricardo, Ferrer, Maria Florencia, Gomez, Ricardo Martin, Montes de Oca, Daniela Paula, Nagel, Ariel Gastón, Nally, Jarlath E., Rípodas, Ana L., Scharrig Fernandez, Maria Emilia, Schattner, Mirta Ana   +10 more
core   +3 more sources