Results 191 to 200 of about 7,418,451 (334)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Corrigendum: Dual Host and Pathogen RNA-Seq Analysis Unravels Chicken Genes Potentially Involved in Resistance to Highly Pathogenic Avian Influenza Virus Infection

Frontiers in Immunology, 2022
Albert Perlas, Albert Perlas, Jordi Argilaguet, Kateri Bertran, Raúl Sánchez-González, Raúl Sánchez-González, Miquel Nofrarías, Rosa Valle, Antonio Ramis, Antonio Ramis, Martí Cortey, Natàlia Majó, Natàlia Majó   +12 more
doaj   +1 more source

New insights into the genetic resistance to paratuberculosis in Holstein cattle via single-step genomic evaluation. [PDF]

Genet Sel Evol, 2022
Sanchez MP, Tribout T, Fritz S, Guatteo R, Fourichon C, Schibler L, Delafosse A, Boichard D.   +7 more
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

The cost of host genetic resistance on body condition: Evidence from divergently selected sheep. [PDF]

Evol Appl, 2022
Douhard F, Doeschl-Wilson AB, Corbishley A, Hayward AD, Marcon D, Weisbecker JL, Aguerre S, Bordes L, Jacquiet P, McNeilly TN, Sallé G, Moreno-Romieux C.   +11 more
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

RESISTENCIA A SEQUÍA DE LINEAS Y VARIEDADES DE FRIJOL NEGRO TROPICAL

Tropical and Subtropical Agroecosystems, 2011
Los objetivos de esta investigación fueron: clasificar genotipos de frijol negro por su tolerancia a sequía e identificar los de mayor eficiencia en el rendimiento en condiciones de riego y sequía.
Ernesto Lopez Salinas, Oscar Hugo Tosquy Valle, Jorge Alberto Acosta Gallegos, Bernardo Villar Sánchez, Francisco Javier Ugalde Acosta   +4 more
doaj  

Evaluation of Single Nucleotide Polymorphisms (SNPs) Associated with Genetic Resistance to Bovine Paratuberculosis in Marchigiana Beef Cattle, an Italian Native Breed. [PDF]

Animals (Basel), 2023
Mazzone P, Di Paolo A, Petrucci L, Torricelli M, Corneli S, Sebastiani C, Ciullo M, Sebastianelli M, Costarelli S, Scoccia E, Sbarra F, Gabbianelli F, Chillemi G, Valentini A, Pezzotti G, Biagetti M.   +15 more
europepmc   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Harnessing genetic resistance to rusts in wheat and integrated rust management methods to develop more durable resistant cultivars. [PDF]

Front Plant Sci, 2022
Mapuranga J, Zhang N, Zhang L, Liu W, Chang J, Yang W.   +5 more
europepmc   +1 more source