Results 11 to 20 of about 445,590 (261)
Journal of Clinical and Preventive Cardiology, 2021 Background and Aims: Along with the conventional risk factors and based on the Framingham risk score, a preventive measure can be targeted in those subjects who are in risk category.
Geetha Bhaktha, Shivananda Nayak
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Body Mass Index Genetic Risk Score and Endometrial Cancer Risk. [PDF]
PLoS ONE, 2015 Genome-wide association studies (GWAS) have identified common variants that predispose individuals to a higher body mass index (BMI), an independent risk factor for endometrial cancer.
Jennifer Prescott +24 more
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Integrating Genetics and Social Science: Genetic Risk Scores [PDF]
Biodemography and Social Biology, 2014 The sequencing of the human genome and the advent of low-cost genome-wide assays that generate millions of observations of individual genomes in a matter of hours constitute a disruptive innovation for social science. Many public use social science datasets have or will soon add genome-wide genetic data.
Daniel W, Belsky, Salomon, Israel
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Air pollution, genetic factors and the risk of osteoporosis: A prospective study in the UK biobank
Frontiers in Public Health, 2023 PurposeTo reveal relationship between air pollution exposure and osteoporosis (OP) risk.MethodsBased on large-scale data from the UK Biobank, we evaluated the relationship between OP risk and several air pollutants.
Xing-Hao Yu +9 more
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Genetic Risk Score and Risk of Myocardial Infarction in Hispanics [PDF]
Circulation, 2011 Background— Genome-wide association studies have identified loci associated with coronary heart disease in whites of European ancestry. This study evaluated whether genetic markers previously identified in whites are associated with nonfatal acute myocardial infarction (MI) in Hispanics ...
Lu, Qi +5 more
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Cancer Medicine, 2021 Background The incorporation of genetic variables into risk scores for predicting venous thromboembolic events (VTE) could improve their capacity to identify those patients for whom thromboprophylaxis would be most beneficial. Proof‐of‐concept of this is
Mariana Bastos‐Oreiro +9 more
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Genetic Risk Score for Essential Hypertension and Risk of Preeclampsia [PDF]
American Journal of Hypertension, 2015 Preeclampsia is a hypertensive complication of pregnancy characterized by novel onset of hypertension after 20 weeks gestation, accompanied by proteinuria. Epidemiological evidence suggests that genetic susceptibility exists for preeclampsia; however, whether preeclampsia is the result of underlying genetic risk for essential hypertension has yet to be
Caitlin J, Smith +11 more
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The relationship of genetic risk score with cardiometabolic risk factors: a cross-sectional study
BMC Cardiovascular Disorders, 2022 Background & aims For more than eight decades, cardiovascular disease (CVD) has remained the leading cause of death in the world. CVD risk factors are multifaceted, with genetics and lifestyle both playing a role. The aim of this study was to investigate
Fatemeh Gholami +7 more
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Multilocus Genetic Risk Scores for Venous Thromboembolism Risk Assessment [PDF]
Journal of the American Heart Association, 2014 Background Genetics plays an important role in venous thromboembolism ( VTE ). Factor V Leiden ( FVL or rs6025) and prothrombin gene G20210A ( PT or rs1799963) are ...
Soria, José Manuel +9 more
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Statistical genetics and polygenic risk score for precision medicine [PDF]
Inflammation and Regeneration, 2021 AbstractThe prediction of disease risks is an essential part of personalized medicine, which includes early disease detection, prevention, and intervention. The polygenic risk score (PRS) has become the standard for quantifying genetic liability in predicting disease risks.
Takahiro Konuma, Yukinori Okada
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