Results 31 to 40 of about 8,823,949 (205)
Modelling the Genetic Risk in Age-Related Macular Degeneration [PDF]
, 2012 Late-stage age-related macular degeneration (AMD) is a common sight-threatening disease of the central retina affecting approximately 1 in 30 Caucasians.
Weber, Bernhard H. F. +29 more
core +1 more source
Genetic and epigenetic factors determining NAFLD risk
Molecular Metabolism, 2021 Background: Hepatic steatosis is a common chronic liver disease that can progress into more severe stages of NAFLD or promote the development of life-threatening secondary diseases for some of those affected.
Wenke Jonas, Annette Schürmann
doaj +1 more source
European Urology Open Science, 2022 Background: Reliability of prostate cancer (PCa) genetic risk score (GRS), that is, the concordance between its estimated risk and observed risk, is required for genetic testing at the individual level.
Zhuqing Shi +11 more
doaj +1 more source
Genetic discovery and risk characterization in type 2 diabetes across diverse populations
HGG Advances, 2021 Summary: Genomic discovery and characterization of risk loci for type 2 diabetes (T2D) have been conducted primarily in individuals of European ancestry.
Linda M. Polfus +53 more
doaj +1 more source
Evaluation of body condition score measured throughout lactation as an indicator of fertility in dairy cattle [PDF]
, 2004 Body condition score (BCS) records of primiparous Holstein cows were analyzed both as a single measure per animal and as repeated measures per sire of cow.
Banos, G +3 more
core +1 more source
A genetic risk score combining ten psoriasis risk loci improves disease prediction. [PDF]
PLoS ONE, 2011 Psoriasis is a chronic, immune-mediated skin disease affecting 2-3% of Caucasians. Recent genetic association studies have identified multiple psoriasis risk loci; however, most of these loci contribute only modestly to disease risk.
Haoyan Chen +7 more
doaj +1 more source
Traditional and Genetic Risk Score and Stroke Risk Prediction in Korea [PDF]
Korean Circulation Journal, 2018 Whether using both traditional risk factors and genetic variants for stroke as opposed to using either of the 2 alone improves the prediction of stroke risk remains unclear. The purpose of this study was to compare the predictability of stroke risk between models using traditional risk score (TRS) and genetic risk score (GRS).We used a case-cohort ...
Keum Ji Jung +4 more
openaire +3 more sources
Evaluation of a Genetic Risk Score for Diagnosis of Psoriatic Arthritis [PDF]
Journal of Psoriasis and Psoriatic Arthritis, 2020 Background: Diagnosis of psoriatic arthritis (PsA) can be challenging, resulting in delays that contribute to irreversible joint damage, reduced quality of life, and increased mortality. Objective: Use genetic markers to develop and ...
Mary Patricia Smith +8 more
openaire +4 more sources
Brain structural alterations, genetic risk variants and the onset of psychosis [PDF]
, 2015 One of the central motivations behind research of the at-risk mental state is to prevent or delay potential transition to psychosis and further progression to schizophrenia, by studying the early signs and symptoms without potential confounding effects ...
Harrisberger, Fabienne
core +1 more source
Reviews in Cardiovascular Medicine, 2023 Background: Using a genetic risk score (GRS) to predict coronary heart disease (CHD) may detect disease earlier. The current study aims to assess whether GRS is associated with CHD incidence and whether it is clinically useful for improving prediction ...
Hyunok Yun, Ji Eun Lim, Eun Young Lee
doaj +1 more source