Results 11 to 20 of about 4,360,463 (355)

Genetic Targeting of Adenoviral Vectors [PDF]

open access: hybridMolecular Therapy, 2000
Victor Krasnykh   +2 more
openalex   +5 more sources

Genetic control of vectors [PDF]

open access: yes, 2018
In a context of tighter regulations on approved insecticide molecules, the spread of insecticide resistance in insect vectors of human and animal diseases and the introduction of exotic vectors to new territories call for the development of new pest control methods and strategies.
Bouyer, Jérémy, Marois, Eric
openaire   +2 more sources

A Multifaceted Approach to Optimizing AAV Delivery to the Brain for the Treatment of Neurodegenerative Diseases

open access: yesFrontiers in Neuroscience, 2021
Despite major advancements in gene therapy technologies, there are no approved gene therapies for diseases which predominantly effect the brain. Adeno-associated virus (AAV) vectors have emerged as the most effective delivery vector for gene therapy ...
Jonathan M. Fischell, Paul S. Fishman
doaj   +1 more source

Genetics of Mosquito Vector Competence [PDF]

open access: yesMicrobiology and Molecular Biology Reviews, 2000
SUMMARY Mosquito-borne diseases are responsible for significant human morbidity and mortality throughout the world. Efforts to control mosquito-borne diseases have been impeded, in part, by the development of drug-resistant parasites, insecticide-resistant mosquitoes, and environmental concerns over the application of ...
Brenda T. Beerntsen   +2 more
openaire   +3 more sources

Targeted therapy in age-related macular degeneration (AMD)

open access: yesJournal of Education, Health and Sport, 2020
Introduction and purpose: Age-related macular degeneration (AMD) is a major cause of blindness in highly developed countries, with blindness frequency of 8.7%.
Klaudia Daria Szumna   +4 more
doaj   +1 more source

Genetic and Chemical Capsid Modifications of Adenovirus Vectors to Modulate Vector–Host Interactions

open access: yesViruses, 2021
Adenovirus-based vectors are playing an important role as efficacious genetic vaccines to fight the current COVID-19 pandemic. Furthermore, they have an enormous potential as oncolytic vectors for virotherapy and as vectors for classic gene therapy ...
Denice Weklak   +5 more
doaj   +1 more source

Overview of paratransgenesis as a strategy to control pathogen transmission by insect vectors

open access: yesParasites & Vectors, 2022
This article presents an overview of paratransgenesis as a strategy to control pathogen transmission by insect vectors. It first briefly summarises some of the disease-causing pathogens vectored by insects and emphasises the need for innovative control ...
N. Ratcliffe   +6 more
semanticscholar   +1 more source

An optimized retroviral toolbox for overexpression and genetic perturbation of primary lymphocytes

open access: yesBiology Open, 2022
Genetic manipulation of primary lymphocytes is crucial for both clinical purposes and fundamental research. Despite their broad use, we encountered a paucity of data on systematic comparison and optimization of retroviral vectors, the workhorses of ...
Lieve E. H. van der Donk   +7 more
doaj   +1 more source

Molecular Genetic Manipulation of Vector Mosquitoes [PDF]

open access: yesCell Host & Microbe, 2008
Genetic strategies for reducing populations of vector mosquitoes or replacing them with those that are not able to transmit pathogens benefit greatly from molecular tools that allow gene manipulation and transgenesis. Mosquito genome sequences and associated EST (expressed sequence tags) databases enable large-scale investigations to provide new ...
Olle Terenius   +3 more
openaire   +3 more sources

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