Results 31 to 40 of about 123,260 (289)
Genetic diversity of the African malaria vector Anopheles gambiae [PDF]
Nature, 2017 The sustainability of malaria control in Africa is threatened by the rise of insecticide resistance in Anopheles mosquitoes, which transmit the disease. To gain a deeper understanding of how mosquito populations are evolving, here we sequenced the genomes of 765 specimens of Anopheles gambiae and Anopheles coluzzii sampled from 15 locations across ...
Nohal Elissa +70 more
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Онкогематология, 2022 By present time safety problems of gene therapy are widely discussed among scientists of all world. In this review results of clinical researches are summarized; explanations concerning side effects of vectors integration are given; factors that can ...
S. E. Ipatov, S. A. Roumiantsev
doaj
Beyond Gene Delivery: Strategies to Engineer the Surfaces of Viral Vectors
Biomedicines, 2013 Viral vectors have been extensively studied due to their great transduction efficiency compared to non-viral vectors. These vectors have been used extensively in gene therapy, enabling the comprehension of, not only the advantages of these vectors, but ...
Cristian Capasso +2 more
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Genetic Manipulation of Ticks: A Paradigm Shift in Tick and Tick-Borne Diseases Research
Frontiers in Cellular and Infection Microbiology, 2021 Ticks are obligate hematophagous arthropods that are distributed worldwide and are one of the most important vectors of pathogens affecting humans and animals.
Andrew Nuss +3 more
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Use of herpes virus amplicon vectors to study brain disorders
BioTechniques, 2005 There is an enormous initiative to establish the genetic basis for disorders of brain function. Unfortunately, genetic intervention is not accomplished easily in the nervous system.
Rachael L. Neve +3 more
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Journal of Biomedical Science, 2022 Viruses are naturally endowed with the capacity to transfer genetic material between cells. Following early skepticism, engineered viruses have been used to transfer genetic information into thousands of patients, and genetic therapies are currently ...
Jonas Holst Wolff, Jacob Giehm Mikkelsen
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Genetic modification of baculovirus expression vectors
Virologica Sinica, 2012 As a protein expression vector, the baculovirus demonstrates many advantages over other vectors. With the development of biotechnology, baculoviral vectors have been genetically modified to facilitate high level expression of heterologous proteins in both insect and mammalian cells.
Shufen Li +3 more
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mBio, 2020 Red blood cell (RBC) invasion by Plasmodium merozoites requires multiple steps that are regulated by signaling pathways. Exposure of P. falciparum merozoites to the physiological signal of low K+, as found in blood plasma, leads to a rise in cytosolic ...
Kunal R. More +13 more
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Simulating population genetics of pathogen vectors in changing landscapes: guidelines and application with Triatoma brasiliensis. [PDF]
PLoS Neglected Tropical Diseases, 2014 BACKGROUND:Understanding the mechanisms that influence the population dynamics and spatial genetic structure of the vectors of pathogens infecting humans is a central issue in tropical epidemiology.
Francois Rebaudo +5 more
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Genetics of Major Insect Vectors
, 2011 Publisher Summary Vector-borne diseases are responsible for a substantial portion of the global disease. Control of insect vectors is often the best and sometimes the only way to protect the population from these destructive diseases. This chapter reviews vector genetics of three of the most important vector-borne diseases that have much to contribute
Dorn, P.L. +4 more
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