Results 1 to 10 of about 277,970 (322)

Protocol for live imaging of bacteria-cell interactions in genetically modified mouse small intestinal organoids [PDF]

STAR Protocols, 2023
Summary: Here, we present a protocol for microinjection of bacteria into mouse small intestinal organoids that recapitulates the natural route of infection of intestinal epithelial cells from the intestinal lumen.
Minhee Kim, Cindy Fèvre, Morgane Lavina, Olivier Disson, Marc Lecuit   +4 more
doaj   +3 more sources

Role of NF-κB in Ageing and Age-Related Diseases: Lessons from Genetically Modified Mouse Models [PDF]

Cells, 2021
Ageing is a complex process, induced by multifaceted interaction of genetic, epigenetic, and environmental factors. It is manifested by a decline in the physiological functions of organisms and associated to the development of age-related chronic ...
Verónica A. García-García, Josefa P. Alameda, Angustias Page, María Llanos Casanova   +3 more
doaj   +4 more sources

Ghrelin and eating behavior: evidence and insights from genetically-modified mouse models [PDF]

Frontiers in Neuroscience, 2013
Ghrelin is an octanoylated peptide hormone, produced by endocrine cells of the stomach, which acts in the brain to increase food intake and body weight.
Aki eUchida, Jeffrey M. Zigman, Mario ePerello   +2 more
doaj   +4 more sources

Probing the Scope and Mechanisms of Calcitriol Actions Using Genetically Modified Mouse Models [PDF]

JBMR Plus, 2021
Genetically modified mice have provided novel insights into the mechanisms of activation and inactivation of vitamin D, and in the process have provided phenocopies of acquired human disease such as rickets and osteomalacia and inherited diseases such as
Dengshun Miao, David Goltzman
doaj   +2 more sources

Genetically Modified Mouse Models of Congenital Diaphragmatic Hernia: Opportunities and Limitations for Studying Altered Lung Development. [PDF]

Front Pediatr, 2022
Friedmacher F, Rolle U, Puri P.
europepmc   +3 more sources

Eradication of Aspiculuris tetraptera in various immunodeficient mouse models using ivermectin: a case report [PDF]

Laboratory Animal Research
Background Despite advancements in laboratory animal facility management, pinworm infections remain a persistent issue in immunodeficient mouse colonies.
Ji-Hun Lee, Eun-Seon Yoo, Na-Won Kim, Han-Bi Jeong, Ah-Reum Kang, Sun-Min Seo, Young-Jun Park, Byeong-Cheol Kang, Yang-Kyu Choi   +8 more
doaj   +2 more sources

Two new genetically modified mouse alleles labeling distinct phases of retinal ganglion cell development by fluorescent proteins. [PDF]

Dev Dyn, 2020
Ge Y, Wu F, Cheng M, Bard J, Mu X.
europepmc   +5 more sources

Altered balance of excitatory and inhibitory learning in a genetically modified mouse model of glutamatergic dysfunction relevant to schizophrenia. [PDF]

Sci Rep, 2017
Sanderson DJ, Lee A, Sprengel R, Seeburg PH, Harrison PJ, Bannerman DM.   +5 more
europepmc   +3 more sources

Novel Genetically Modified Mouse Model to Assess Soman-Induced Toxicity and Medical Countermeasure Efficacy: Human Acetylcholinesterase Knock-in Serum Carboxylesterase Knockout Mice. [PDF]

Int J Mol Sci, 2021
Marrero-Rosado BM, Stone MF, de Araujo Furtado M, Schultz CR, Cadieux CL, Lumley LA.   +5 more
europepmc   +3 more sources

Lipidomic and metabolomic characterization of a genetically modified mouse model of the early stages of human type 1 diabetes pathogenesis. [PDF]

Metabolomics, 2016
Overgaard AJ, Weir JM, De Souza DP, Tull D, Haase C, Meikle PJ, Pociot F.   +6 more
europepmc   +3 more sources