Results 111 to 120 of about 451,686 (317)
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Cut–dip–budding delivery system enables genetic modifications in plants without tissue culture
The Innovation, 2023 Of the more than 370 000 species of higher plants in nature, fewer than 0.1% can be genetically modified due to limitations of the current gene delivery systems.
Xuesong Cao +12 more
doaj
Tourte Y. Genetically modified organisms: transgenesis in plants. [PDF]
, 2003 Huw Jones
openalex +1 more source
, 2011 The regulation of genetically modified products pursuant to statutes enacted decades prior to the advent of biotechnology has led to a system that is passive rather than proactive about risks, that has difficulty adapting to biotechnology advances, and ...
Gregory N. Mandel
semanticscholar +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Acta Scientiarum Polonorum: Hortorum Cultus, 2013 Green biotechnology plays an important role in the modern agriculture. Recent progress in molecular biology and genetic engineering provides an opportunity of obtaining transgenic plants with improved characteristics, such as yield parameters ...
Magda Zapalska, Krzysztof Kowalczyk
doaj
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
A decade of European field trials with genetically modified plants [PDF]
, 2004 K. Lheureux, Klaus Menrad
openalex +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Genetically Modified Plants For Sustainable Food Security
, 2017 This record was migrated from the OpenDepot repository service in June, 2017 before shutting down.
openaire +1 more source