Results 11 to 20 of about 7,649,767 (328)

Rewriting Human History and Empowering Indigenous Communities with Genome Editing Tools. [PDF]

, 2020
Appropriate empirical-based evidence and detailed theoretical considerations should be used for evolutionary explanations of phenotypic variation observed in the field of human population genetics (especially Indigenous populations). Investigators within
Fox, Keolu, Komor, Alexis C, Rallapalli, Kartik Lakshmi   +2 more
core   +2 more sources

Diferencias genéticas entre poblaciones de Aedes aegypti de municipios del norte de Colombia, con baja y alta incidencia de dengue

Biomédica: revista del Instituto Nacional de Salud, 2013
Introducción. Aedes aegypti es el principal vector del dengue en zonas urbanas. A pesar de su importancia epidemiológica, se desconoce la variabilidad genética de las poblaciones del vector en Colombia. Objetivo.
Sandy Milena Caldera, María Cristina Jaramillo, Suljey Cochero, Alveiro Pérez-Doria, Eduar Elías Bejarano   +4 more
doaj   +1 more source

Population genetics in microchannels

Proceedings of the National Academy of Sciences, 2022
Significance Many microbial populations proliferate in small channels. In such environments, reproducing cells organize in parallel lanes. Reproducing cells shift these lanes, potentially expelling other cells from the channel. In this paper, we combine theory and experiments to understand how these dynamics affects the diversity
Anzhelika Koldaeva, Hsieh-Fu Tsai, Amy Q. Shen, Simone Pigolotti   +3 more
openaire   +3 more sources

The nk model and population genetics [PDF]

, 2005
The nk model of fitness interactions is examined. This model has been used by previous authors to investigate the effects of fitness epistasis on substitution dynamics in molecular evolution, and to make broader claims about the importance of epistasis ...
Barton, Barton, Bergman, Burch, Coyne, Edmands, Elena, Elena, Felsenstein, Fisher, Fitch, Fontana, Fraser, Gavrilets, Gillespie, Gillespie, Gillespie, Gillespie, Gumbel, Hansen, Hartl, Jeong, Kauffman, Kauffman, Kauffman, Kichler Holder, Kimura, Kimura, Kondrashov, Korona, Lenski, Macken, Mani, Maynard Smith, Moore, Ohta, Ohta, Ohta, Ohta, Orr, Orr, Orr, Peck, Perelson, Phillips, Provine, Schrag, Solow, Stephan, Tachida, Tachida, Weinberger, Welch, Whitlock, Zeng   +54 more
core   +2 more sources

Chromosomal phase improves aneuploidy detection in non-invasive prenatal testing at low fetal DNA fractions

Scientific Reports, 2022
Non-invasive prenatal testing (NIPT) to detect fetal aneuploidy by sequencing the cell-free DNA (cfDNA) in maternal plasma is being broadly adopted. To detect fetal aneuploidies from maternal plasma, where fetal DNA is mixed with far-larger amounts of ...
Giulio Genovese, Curtis J. Mello, Po-Ru Loh, Robert E. Handsaker, Seva Kashin, Christopher W. Whelan, Lucy A. Bayer-Zwirello, Steven A. McCarroll   +7 more
doaj   +1 more source

Population genetics of the coral Acropora millepora: Toward genomic prediction of bleaching

Science, 2020
Conservation help from genomics Corals worldwide are under threat from rising sea temperatures and pollution. One response to heat stress is coral bleaching—the loss of photosynthetic endosymbionts that provide energy for the coral. Fuller et al. present
Zachary L. Fuller, V. J. Mocellin, Luke A. Morris, N. Cantin, Jihanne Shepherd, Luke A. Sarre, J. Peng, Yi Liao, Joseph K. Pickrell, P. Andolfatto, M. Matz, L. Bay, M. Przeworski   +12 more
semanticscholar   +1 more source

Pedigree Analysis: A Team-Based Learning Activity

MedEdPORTAL, 2017
Introduction Regardless of their specialty, physicians, particularly those practicing primary care in rural areas, typically encounter genetic conditions.
Jack Thatcher, Patty Canfield, Laurie Bauer, Brian N. Griffith   +3 more
doaj   +1 more source

The Pennsylvania grotto sculpin: population genetics [PDF]

Subterranean Biology, 2021
The Pennsylvania grotto sculpin is known from just two caves of the Nippenose Valley in central Pennsylvania, USA. They exhibit emergent troglobitic morphological traits and are the second northern-most cave adapted fish in the world.
Luis Espinasa, Drake M. Smith, Julianna M. Lindquist   +2 more
doaj   +3 more sources

In silico characterization of coding and non-coding SNPs of the androgen receptor gene

Informatics in Medicine Unlocked, 2021
The Androgen Receptor (AR), an important ligand-dependent nuclear transcription factor, encoded by the AR gene, functions in regulating the cell proliferation, migration, invasion, and apoptosis pathways. Single nucleotide polymorphisms (SNPs) of AR have
Maisha Adiba, Tonmoy Das, Anik Paul, Ashish Das, Sajib Chakraborty, Md Ismail Hosen, A.H.M. Nurun Nabi   +6 more
doaj   +1 more source

Population Genetics of Rare Variants and Complex Diseases [PDF]

, 2012
Identifying drivers of complex traits from the noisy signals of genetic variation obtained from high throughput genome sequencing technologies is a central challenge faced by human geneticists today.
Hernandez, Ryan D., Maher, M. Cyrus, Torgerson, Dara G., Uricchio, Lawrence H.   +3 more
core   +2 more sources