Results 141 to 150 of about 100,181 (178)

Single‑cell sequencing, genetics, and epigenetics reveal mesenchymal stem cell senescence in osteoarthritis (Review). [PDF]

Int J Mol Med
Tan D, Huang Z, Zhao Z, Chen X, Liu J, Wang D, Deng Z, Li W.   +7 more
europepmc   +1 more source

Identification of Stage-Specific microRNAs that Govern the Early Stages of Sequential Oral Oncogenesis by Strategically Bridging Human Genetics with Epigenetics and Utilizing an Animal Model. [PDF]

Int J Mol Sci
Gintoni I, Vassiliou S, Chrousos GP, Yapijakis C.   +3 more
europepmc   +1 more source

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Genetics and Epigenetics of Keloids

Advances in Wound Care, 2022
Significance: Keloid scarring is cosmetically disfiguring, psychosocially distressing, and can be physically disabling. The pathophysiology of keloid formation is poorly understood and subsequently, treatment options are ill defined, limited, and largely unsatisfactory.
Dennias Tonderai Nyika, Nonhlanhla P. Khumalo, Ardeshir Bayat   +2 more
openaire   +2 more sources

Genetics and epigenetics of allergy

Current Opinion in Allergy & Clinical Immunology, 2020
Purpose of review Allergic diseases are prototypic examples for gene × environment-wide interactions. This review considers the current evidence for genetic and epigenetic mechanisms in allergic diseases and highlights barriers and facilitators for the implementation of these novel tools both for research and clinical practice.
Ioana, Agache, Catalina, Cojanu, Alexandru, Laculiceanu, Liliana, Rogozea   +3 more
openaire   +2 more sources

Genetics and epigenetics of CLL

Leukemia & Lymphoma, 2022
Chronic lymphocytic leukemia (CLL) has a heterogeneous biological behavior, which is highly influenced by its immunogenetic, epigenetic, and genomic properties. The remarkably variable clinical course of the disease has been associated with genetic features such as chromosomal abnormalities, the presence of either high or low numbers of somatic ...
Pamella, Paul, Georg, Stüssi, Alessio, Bruscaggin, Davide, Rossi   +3 more
openaire   +2 more sources

Genetics and epigenetics of osteoarthritis

Maturitas, 2012
Osteoarthritis (OA) is a common age-related disease that affects the tissues of the synovial joint, leading to loss of function and pain. It impacts on both patient morbidity and mortality. It is a complex, polygenic disease that lacks any large-effect susceptibility loci.
Reynard LN, Loughlin J
openaire   +3 more sources

Common Genetic and Epigenetic Syndromes

Pediatric Clinics of North America, 2015
Cytogenetic anomalies should be considered in individuals with multiple congenital anomalies. DNA methylation analysis is the most sensitive initial test in evaluating for Prader-Willi and Angelman syndromes. The timely identification of cytogenetic anomalies allows for prompt initiation of early intervention services to maximize the potential of every
Darius J, Adams, David A, Clark
openaire   +2 more sources