Results 141 to 150 of about 44,113 (259)

Cancer‐Associated Fibroblasts Functions as Multifunctional Architects of the Tumor Stroma and Represent Emerging Therapeutic Vulnerabilities

Advanced Science, EarlyView.
ABSTRACT Cancer‐associated fibroblasts (CAFs) are the predominant stromal components within the tumor microenvironment (TME), playing multifaceted roles in cancer progression through dynamic interactions with neoplastic and immune cells. Emerging evidence has revealed remarkable heterogeneity and plasticity of CAFs, which originate from diverse ...
Rujiao Liu, Lili Su, Shuiping Gao, Wenting Liu, Hongxia Wang   +4 more
wiley   +1 more source

Genetics and Epigenetics of Chemoinduced Oral Mucositis in Paediatric Patients with Haematological Malignancies-A Review. [PDF]

Epigenomes
Guimarães JR, Viana Filho JMC, de Oliveira NFP.   +2 more
europepmc   +1 more source

Genetics and epigenetics of stress: New avenues for an old concept. [PDF]

Neurobiol Stress, 2023
Soliva-Estruch M, Tamashiro KL, Daskalakis NP.   +2 more
europepmc   +1 more source

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

Advanced Science, EarlyView.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency, Tao Cui, Yimei Cai, Chloe Lok, Rachel E. Nokku, Ruoxian Huang, Grace L. Chu, Yumeng Xie, Saleem W. Abu‐Tayeh, Kaikai He, Chengjie Qiu, Junyi Wang, Paxton M. Paganelli, Ting Wang, Gabrielle Williams, Sreejith Nair, Huadong Pei, Dion K. Dickman, Stefano Vicini, Tingting Wang   +19 more
wiley   +1 more source

Genetics and Epigenetics: Implications for the Life Course of Gestational Diabetes. [PDF]

Int J Mol Sci, 2023
Lowe WL.
europepmc   +1 more source

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

Advanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet, Sara Pugliese, Jordi Bruna, Daniel Ruiz‐Molina, Salvio Suárez‐García, Victor J. Yuste   +5 more
wiley   +1 more source

Translational Impact of Genetics and Epigenetics of CGRP System on Chronic Migraine Treatment with Onabotulinumtoxin A and Other Biotech Drugs. [PDF]

Toxins (Basel)
Scuteri D, Martelletti P.
europepmc   +1 more source

Genetics and epigenetics of Pinus nigra populations with differential exposure to air pollution. [PDF]

Front Plant Sci, 2023
Katsidi EC, Avramidou EV, Ganopoulos I, Barbas E, Doulis A, Triantafyllou A, Aravanopoulos FA.   +6 more
europepmc   +1 more source

Heuristically Adaptive Diffusion‐Model Evolutionary Strategy

Advanced Science, EarlyView.
Building on the mathematical equivalence between diffusion models and evolutionary algorithms, researchers demonstrate unprecedented control over evolutionary optimization through conditional diffusion. By training diffusion models to associate parameters with specific traits, they can guide evolution toward solutions exhibiting desired behaviors ...
Benedikt Hartl, Yanbo Zhang, Hananel Hazan, Michael Levin   +3 more
wiley   +1 more source

Food Allergy Genetics and Epigenetics: A Review of Genome-Wide Association Studies. [PDF]

Allergy
Arnau-Soler A, Tremblay BL, Sun Y, Madore AM, Simard M, Kersten ETG, Ghauri A, Marenholz I, Eiwegger T, Simons E, Chan ES, Nadeau K, Sampath V, Mazer BD, Elliott S, Hampson C, Soller L, Sandford A, Begin P, Hui J, Wilken BF, Gerdts J, Bourkas A, Ellis AK, Vasileva D, Clarke A, Eslami A, Ben-Shoshan M, Martino D, Daley D, Koppelman GH, Laprise C, Lee YA, Asai Y.   +33 more
europepmc   +1 more source