Results 211 to 220 of about 44,113 (259)
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Common Genetic and Epigenetic Syndromes
Pediatric Clinics of North America, 2015Cytogenetic anomalies should be considered in individuals with multiple congenital anomalies. DNA methylation analysis is the most sensitive initial test in evaluating for Prader-Willi and Angelman syndromes. The timely identification of cytogenetic anomalies allows for prompt initiation of early intervention services to maximize the potential of every
Darius J, Adams, David A, Clark
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Genetics and epigenetics of hepatoblastoma
Pediatric Blood & Cancer, 2012AbstractA number of unique genetic features are observed in hepatoblastoma that have provided insights into the origins of hepatoblastoma. Hallmark cytogenetic changes in hepatoblastoma include the acquisition of additional copies of whole chromosomes and a recurring unbalanced translocation involving 1q.
Gail E, Tomlinson, Roland, Kappler
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Genetics, epigenetics, and causation
American Journal of Orthodontics, 1981Abstract Much of the continuing controversy concerning the roles of genomic and nongenomic (epigenetic) processes in the regulation (causation) of growth is resolved by an analysis of the several types of causation. It can be shown that the combination of genomic and epigenetic factors is a necessary cause of craniofacial growth.
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Systemic sclerosis: Genetics and epigenetics
Journal of Autoimmunity, 2013Systemic sclerosis (SSc) is an autoimmune disease characterized by immune abnormalities, vascular obliteration, excessive extracellular matrix deposition, and fibrosis of the skin and/or internal organs. To date, the exact etiology of this complicated disease remains unknown.
Yangyang, Luo +4 more
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2019
Genetic influences on human disease can be understood in the context of essential and exacerbating causes. Alleles are essential causes when they are required for these diseases to occur. Severe diseases with essential genetic causes are rare unless they provide a compensating benefit in evolutionary fitness (accrued through increases in survival and ...
Paul W. Ewald, Holly A. Swain Ewald
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Genetic influences on human disease can be understood in the context of essential and exacerbating causes. Alleles are essential causes when they are required for these diseases to occur. Severe diseases with essential genetic causes are rare unless they provide a compensating benefit in evolutionary fitness (accrued through increases in survival and ...
Paul W. Ewald, Holly A. Swain Ewald
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Hepatocarcinoma: genetic and epigenetic features
Minerva Gastroenterology, 2017HCC is the third leading cause of cancer-related deaths worldwide, accounting for about 1 million deaths annually. The incidence of HCC is highest in Asia and Africa, where the endemic high prevalence of hepatitis B and hepatitis C strongly predisposes to the development of chronic liver disease and subsequent development of HCC.
Lombardi, Angela +4 more
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Behavioral Genetics, Genetics, and Epigenetics
2013When considering how “nature” and “nurture” contribute to development, psychologists often take the former to mean “influenced by genes.” Traditionally, behavioral geneticists have used twin and adoption studies to assess the extent of genetic influence on various behaviors.
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The Genetics and Epigenetics of Fatigue
PM&R, 2010AbstractFatigue is a common symptom and includes both physical and mental components. It can be associated with a variety of different syndromes and diseases, but in many cases is not associated with other comorbid conditions. Most humans have experienced acute fatigue in relation to different stressors.
Landmark-Høyvik H +7 more
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Epigenetic and Genetics Factors
2023Despite variations in the morphology and behaviors of human body cells, every single cell in our body is composed of identical DNA material. The variation in cell phenotypes is a result of a specific regulatory mechanism known as epigenetics, by which gene expression undergoes some modifications without the actual nucleotide sequence being affected [1].
Abeer A. Alsofyani, Yazan Samih Said
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Genetics and epigenetics in vitiligo
Journal of Dermatological ScienceVitiligo, a complex autoimmune disorder characterized by melanocyte destruction, arises from an intricate interplay of genetic, epigenetic, immune, and environmental factors. Genome-wide association studies (GWAS) have identified over 50 susceptibility loci, including key genes within the MHC region and those involved in immunity, oxidative stress, and
Ken, Okamura, Tamio, Suzuki
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